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Gene ID: 9179 | AP4M1 Antibody Resource


AP4M1 Antibody Resource
Gene Full Name: 
adaptor-related protein complex 4, mu 1 subunit
Uniprot: 
O00189
Protein Name: 
AP-4 complex subunit mu-1
Nucleotide: 
NM_004722
Alias: 
MU-4;CPSQ3;SPG50;MU-ARP2;
Ensembl: 
ENSG00000221838
Location: 
7q22.1
HPRD: 
03803
NCBI Gene: 
9179
MIM: 
602296

Summary: 
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system. [provided by RefSeq, Jul 2008]
Function: 
Component of the AP-4 complex, a novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. Plays a role in the intracellular trafficking of APP from the trans-Golgi network (TGN) to endosomes, and thereby inhibits amyloidogenic processing of APP.
Subcellular location: 
Golgi apparatus › trans-Golgi network. Membrane › coated pit. Note: Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.
PTM: 
Disease: 
Cerebral palsy, spastic quadriplegic 3 (CPSQ3) [MIM:612936]: A non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals present postnatally with early infantile hypotonia, delayed psychomotor development, strabismus, lack of independent walking and severe mental retardation. They develop progressive spasticity of all limbs with generalized hypertonia, hyperreflexia, and extensor plantar responses by the end of the first year of life. Speech is absent or limited. Pseudobulbar signs, such as drooling, stereotypic laughter, and exaggerated jaw jerk, are part of the clinical picture. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP67367_P050 AP4M1 Antibody - C-terminal region (ARP67367_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP67366_P050 AP4M1 Antibody (ARP67366_P050) Polyclonal Bovine, Dog, Goat, Guinea pig, Horse, Human, Mouse, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB12877 AP4M1 antibody - center region (OAAB12877) Human WB 400ul $289 Details
Polyclonal Antibody OAGA01115 AP4M1 antibody (OAGA01115) Polyclonal Human IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details

Show all AP4M1 antibodies


Product Images
AP4M1 Antibody - C-terminal region (ARP67367_P050) in Human 293T cells using Western Blot

Sample Type: Human 293T

AP4M1 antibody - center region (OAAB12877) in CEM cells using Western Blot

Sample Type: CEM


AP4M1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP67366 African elephant AP4M1 antibody; Loxodonta africana AP4M1 antibody G3TPV0 86.0%
ARP67367 African elephant AP4M1 antibody; Loxodonta africana AP4M1 antibody G3TPV0 86.0%
ARP67366 Bovine AP4M1 antibody; Bos taurus AP4M1 antibody Q29RY8 100.0%
ARP67367 Bovine AP4M1 antibody; Bos taurus AP4M1 antibody Q29RY8 93.0%
ARP67366 Cat AP4M1 antibody; Felis catus AP4M1 antibody M3WZA5 100.0%
ARP67367 Cat AP4M1 antibody; Felis catus AP4M1 antibody M3WZA5 79.0%
ARP67366 Chimpanzee AP4M1 antibody; Pan troglodytes AP4M1 antibody H2QV17 100.0%
ARP67367 Chimpanzee AP4M1 antibody; Pan troglodytes AP4M1 antibody H2QV17 100.0%
ARP67367 Chinese softshell turtle AP4M1 antibody; Pelodiscus sinensis AP4M1 antibody K7FVT4 91.0%
ARP67366 Dog AP4M1 antibody; Canis familiaris AP4M1 antibody E2RED8 100.0%
ARP67367 Dog AP4M1 antibody; Canis familiaris AP4M1 antibody E2RED8 86.0%
ARP67366 European domestic ferret AP4M1 antibody; Mustela putorius furo AP4M1 antibody M3YHI0 100.0%
ARP67367 European domestic ferret AP4M1 antibody; Mustela putorius furo AP4M1 antibody M3YHI0 86.0%
ARP67366 Giant panda AP4M1 antibody; Ailuropoda melanoleuca AP4M1 antibody G1LXB7 100.0%
ARP67367 Giant panda AP4M1 antibody; Ailuropoda melanoleuca AP4M1 antibody G1LXB7 86.0%
ARP67366 Goat AP4M1 antibody; Capra hircus AP4M1 antibody G1DG09 100.0%
ARP67367 Goat AP4M1 antibody; Capra hircus AP4M1 antibody G1DG09 93.0%
ARP67366 Gray short-tailed opossum AP4M1 antibody; Monodelphis domestica AP4M1 antibody F6TVH4 92.0%
ARP67367 Gray short-tailed opossum AP4M1 antibody; Monodelphis domestica AP4M1 antibody F6TVH4 86.0%
ARP67366 Horse AP4M1 antibody; Equus caballus AP4M1 antibody F7DV08 93.0%
ARP67367 Horse AP4M1 antibody; Equus caballus AP4M1 antibody F7DV08 93.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9IZL5 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9IZL5 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9JC87 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9JC87 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9JMG3 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9JWL4 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody C9JWL4 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody F8WCR6 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody H0Y6K1 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody H7BZV3 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody H7C0A0 100.0%
ARP67366 Human AP4M1 antibody; Homo sapiens AP4M1 antibody O00189 100.0%
ARP67367 Human AP4M1 antibody; Homo sapiens AP4M1 antibody O00189 100.0%
ARP67366 Mouse AP4M1 antibody; Mus musculus AP4M1 antibody Q8CD17 100.0%
ARP67366 Mouse AP4M1 antibody; Mus musculus AP4M1 antibody Q9JKC7 100.0%
ARP67367 Mouse AP4M1 antibody; Mus musculus AP4M1 antibody Q8CD17 86.0%
ARP67367 Mouse AP4M1 antibody; Mus musculus AP4M1 antibody Q9JKC7 86.0%
ARP67366 Northern white-cheeked gibbon AP4M1 antibody; Nomascus leucogenys AP4M1 antibody G1RLB5 100.0%
ARP67367 Northern white-cheeked gibbon AP4M1 antibody; Nomascus leucogenys AP4M1 antibody G1RLB5 100.0%
ARP67366 Rabbit AP4M1 antibody; Oryctolagus cuniculus AP4M1 antibody G1SD07 100.0%
ARP67367 Rabbit AP4M1 antibody; Oryctolagus cuniculus AP4M1 antibody G1SD07 93.0%
ARP67366 Rat AP4M1 antibody; Rattus norvegicus AP4M1 antibody Q2PWT8 100.0%
ARP67367 Rat AP4M1 antibody; Rattus norvegicus AP4M1 antibody Q2PWT8 86.0%
ARP67366 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F6YHH7 100.0%
ARP67367 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F6YHH7 100.0%
ARP67366 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F7DJN3 100.0%
ARP67367 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F7DJN3 100.0%
ARP67366 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F7DPT6 100.0%
ARP67367 Rhesus macaque AP4M1 antibody; Macaca mulatta AP4M1 antibody F7DPT6 100.0%
ARP67366 Small-eared galago AP4M1 antibody; Otolemur garnettii AP4M1 antibody H0WU55 100.0%
ARP67367 Small-eared galago AP4M1 antibody; Otolemur garnettii AP4M1 antibody H0WU55 93.0%
ARP67366 Sumatran orangutan AP4M1 antibody; Pongo abelii AP4M1 antibody H2PLL6 100.0%
ARP67367 Sumatran orangutan AP4M1 antibody; Pongo abelii AP4M1 antibody H2PLL6 100.0%
ARP67366 Tasmanian devil AP4M1 antibody; Sarcophilus harrisii AP4M1 antibody G3WDK3 92.0%
ARP67366 Tasmanian devil AP4M1 antibody; Sarcophilus harrisii AP4M1 antibody G3WDK4 92.0%
ARP67367 Tasmanian devil AP4M1 antibody; Sarcophilus harrisii AP4M1 antibody G3WDK3 86.0%
ARP67367 Tasmanian devil AP4M1 antibody; Sarcophilus harrisii AP4M1 antibody G3WDK4 86.0%
ARP67366 Thirteen-lined ground squirrel AP4M1 antibody; Spermophilus tridecemlineatus AP4M1 antibody I3MCU4 100.0%
ARP67367 Thirteen-lined ground squirrel AP4M1 antibody; Spermophilus tridecemlineatus AP4M1 antibody I3MCU4 93.0%
ARP67366 White-tufted-ear marmoset AP4M1 antibody; Callithrix jacchus AP4M1 antibody F6QIY4 100.0%
ARP67367 White-tufted-ear marmoset AP4M1 antibody; Callithrix jacchus AP4M1 antibody F6QIY4 100.0%
ARP67366 White-tufted-ear marmoset AP4M1 antibody; Callithrix jacchus AP4M1 antibody F6UF67 100.0%
ARP67367 White-tufted-ear marmoset AP4M1 antibody; Callithrix jacchus AP4M1 antibody F6UF67 100.0%
ARP67366 White-tufted-ear marmoset AP4M1 antibody; Callithrix jacchus AP4M1 antibody F6VMH5 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas209837_at721_B_lymphoblasts4.9004.040Details
BioGPS Gene Atlas209837_atAdipocyte3.8004.040Details
BioGPS Gene Atlas209837_atAdrenalCortex3.9504.040Details
BioGPS Gene Atlas209837_atAdrenalgland3.2504.040Details
BioGPS Gene Atlas209837_atAmygdala4.1004.040Details
BioGPS Gene Atlas209837_atAppendix3.8504.040Details
BioGPS Gene Atlas209837_atAtrioventricularNode2.8004.040Details
BioGPS Gene Atlas209837_atBDCA4+_DentriticCells4.3504.040Details
BioGPS Gene Atlas209837_atBonemarrow3.8004.040Details
BioGPS Gene Atlas209837_atBronchialEpithelialCells3.8504.040Details
BioGPS Gene Atlas209837_atCD105+_Endothelial3.9004.040Details
BioGPS Gene Atlas209837_atCD14+_Monocytes4.1004.040Details
BioGPS Gene Atlas209837_atCD19+_BCells(neg._sel.)4.1504.040Details
BioGPS Gene Atlas209837_atCD33+_Myeloid5.0004.040Details
BioGPS Gene Atlas209837_atCD34+5.1504.040Details
BioGPS Gene Atlas209837_atCD4+_Tcells4.1504.040Details
BioGPS Gene Atlas209837_atCD56+_NKCells4.6004.040Details
BioGPS Gene Atlas209837_atCD71+_EarlyErythroid3.5504.040Details
BioGPS Gene Atlas209837_atCD8+_Tcells3.7504.040Details
BioGPS Gene Atlas209837_atCardiacMyocytes4.8004.040Details
BioGPS Gene Atlas209837_atCaudatenucleus3.5004.040Details
BioGPS Gene Atlas209837_atCerebellum3.1004.040Details
BioGPS Gene Atlas209837_atCerebellumPeduncles4.4004.040Details
BioGPS Gene Atlas209837_atCiliaryGanglion2.6504.040Details
BioGPS Gene Atlas209837_atCingulateCortex3.9504.040Details
BioGPS Gene Atlas209837_atColorectaladenocarcinoma3.9504.040Details
BioGPS Gene Atlas209837_atDorsalRootGanglion2.9004.040Details
BioGPS Gene Atlas209837_atFetalThyroid3.7004.040Details
BioGPS Gene Atlas209837_atFetalbrain4.0504.040Details
BioGPS Gene Atlas209837_atFetalliver3.3004.040Details
BioGPS Gene Atlas209837_atFetallung3.2504.040Details
BioGPS Gene Atlas209837_atGlobusPallidus2.8004.040Details
BioGPS Gene Atlas209837_atHeart4.8504.040Details
BioGPS Gene Atlas209837_atHypothalamus4.3004.040Details
BioGPS Gene Atlas209837_atKidney3.1004.040Details
BioGPS Gene Atlas209837_atLeukemia_chronicMyelogenousK-5623.5004.040Details
BioGPS Gene Atlas209837_atLeukemia_promyelocytic-HL-603.4004.040Details
BioGPS Gene Atlas209837_atLeukemialymphoblastic(MOLT-4)3.6004.040Details
BioGPS Gene Atlas209837_atLiver5.1004.040Details
BioGPS Gene Atlas209837_atLung4.3504.040Details
BioGPS Gene Atlas209837_atLymphnode3.3504.040Details
BioGPS Gene Atlas209837_atLymphoma_burkitts(Daudi)4.9004.040Details
BioGPS Gene Atlas209837_atLymphoma_burkitts(Raji)5.3504.040Details
BioGPS Gene Atlas209837_atMedullaOblongata3.5504.040Details
BioGPS Gene Atlas209837_atOccipitalLobe3.4504.040Details
BioGPS Gene Atlas209837_atOlfactoryBulb3.0504.040Details
BioGPS Gene Atlas209837_atOvary2.5504.040Details
BioGPS Gene Atlas209837_atPancreas3.1004.040Details
BioGPS Gene Atlas209837_atPancreaticIslet4.1004.040Details
BioGPS Gene Atlas209837_atParietalLobe4.0504.040Details
BioGPS Gene Atlas209837_atPituitary5.1004.040Details
BioGPS Gene Atlas209837_atPlacenta4.0504.040Details
BioGPS Gene Atlas209837_atPons3.9004.040Details
BioGPS Gene Atlas209837_atPrefrontalCortex4.8504.040Details
BioGPS Gene Atlas209837_atProstate4.5004.040Details
BioGPS Gene Atlas209837_atSalivarygland3.0504.040Details
BioGPS Gene Atlas209837_atSkeletalMuscle4.4504.040Details
BioGPS Gene Atlas209837_atSkin2.8504.040Details
BioGPS Gene Atlas209837_atSmoothMuscle4.4504.040Details
BioGPS Gene Atlas209837_atSpinalcord5.0504.040Details
BioGPS Gene Atlas209837_atSubthalamicNucleus4.4004.040Details
BioGPS Gene Atlas209837_atSuperiorCervicalGanglion4.2504.040Details
BioGPS Gene Atlas209837_atTemporalLobe3.5004.040Details
BioGPS Gene Atlas209837_atTestis4.4004.040Details
BioGPS Gene Atlas209837_atTestisGermCell5.1504.040Details
BioGPS Gene Atlas209837_atTestisIntersitial3.4504.040Details
BioGPS Gene Atlas209837_atTestisLeydigCell4.9004.040Details
BioGPS Gene Atlas209837_atTestisSeminiferousTubule5.5504.040Details
BioGPS Gene Atlas209837_atThalamus4.1504.040Details
BioGPS Gene Atlas209837_atThymus3.0504.040Details
BioGPS Gene Atlas209837_atThyroid4.9004.040Details
BioGPS Gene Atlas209837_atTongue3.7004.040Details
BioGPS Gene Atlas209837_atTonsil3.7004.040Details
BioGPS Gene Atlas209837_atTrachea3.2004.040Details
BioGPS Gene Atlas209837_atTrigeminalGanglion3.7504.040Details
BioGPS Gene Atlas209837_atUterus3.4004.040Details
BioGPS Gene Atlas209837_atUterusCorpus4.9504.040Details
BioGPS Gene Atlas209837_atWholeBlood4.2504.040Details
BioGPS Gene Atlas209837_atWholebrain5.1004.040Details
BioGPS Gene Atlas209837_atcolon3.8504.040Details
BioGPS Gene Atlas209837_atpineal_day4.8204.040Details
BioGPS Gene Atlas209837_atpineal_night4.7604.040Details
BioGPS Gene Atlas209837_atretina4.6754.040Details
BioGPS Gene Atlas209837_atsmall_intestine3.7504.040Details
BioGPS NCI60209837_at7863.2014.500Details
BioGPS NCI60209837_atA1724.3164.500Details
BioGPS NCI60209837_atA2044.0194.500Details
BioGPS NCI60209837_atA3614.0924.500Details
BioGPS NCI60209837_atA4984.0774.500Details
BioGPS NCI60209837_atA5494.1024.500Details
BioGPS NCI60209837_atACC38.3044.500Details
BioGPS NCI60209837_atACHN6.6904.500Details
BioGPS NCI60209837_atALVA314.1554.500Details
BioGPS NCI60209837_atCAKI14.0974.500Details
BioGPS NCI60209837_atCCRT CEM4.2884.500Details
BioGPS NCI60209837_atCOLO2052.9624.500Details
BioGPS NCI60209837_atDLD14.0304.500Details
BioGPS NCI60209837_atDU1454.2364.500Details
BioGPS NCI60209837_atEKVX4.2984.500Details
BioGPS NCI60209837_atGM1334.0514.500Details
BioGPS NCI60209837_atGM16004.1334.500Details
BioGPS NCI60209837_atGM23134.0664.500Details
BioGPS NCI60209837_atGM23454.1974.500Details
BioGPS NCI60209837_atGM24934.1164.500Details
BioGPS NCI60209837_atGM974.1864.500Details
BioGPS NCI60209837_atHCC29984.0154.500Details
BioGPS NCI60209837_atHCT1164.4634.500Details
BioGPS NCI60209837_atHCT153.9654.500Details
BioGPS NCI60209837_atHEK 293 T-rex4.1094.500Details
BioGPS NCI60209837_atHEK 293T4.0804.500Details
BioGPS NCI60209837_atHEK2934.0704.500Details
BioGPS NCI60209837_atHELA3.9494.500Details
BioGPS NCI60209837_atHEPG24.0504.500Details
BioGPS NCI60209837_atHL604.0884.500Details
BioGPS NCI60209837_atHOP624.0744.500Details
BioGPS NCI60209837_atHOP923.8494.500Details
BioGPS NCI60209837_atHS578T4.1564.500Details
BioGPS NCI60209837_atHSG4.3784.500Details
BioGPS NCI60209837_atHT10804.0264.500Details
BioGPS NCI60209837_atHT294.2144.500Details
BioGPS NCI60209837_atIGROV14.1414.500Details
BioGPS NCI60209837_atIOSE806.3774.500Details
BioGPS NCI60209837_atJURKAT4.0584.500Details
BioGPS NCI60209837_atK5624.1964.500Details
BioGPS NCI60209837_atKM124.1184.500Details
BioGPS NCI60209837_atLN183.9684.500Details
BioGPS NCI60209837_atLNCAP4.8734.500Details
BioGPS NCI60209837_atLOX IMVI6.2354.500Details
BioGPS NCI60209837_atM144.3834.500Details
BioGPS NCI60209837_atMALME 3M4.1874.500Details
BioGPS NCI60209837_atMCF73.9974.500Details
BioGPS NCI60209837_atMD MB2314.0804.500Details
BioGPS NCI60209837_atMDA MB4358.5504.500Details
BioGPS NCI60209837_atMOLT414.7694.500Details
BioGPS NCI60209837_atNCI 4604.0894.500Details
BioGPS NCI60209837_atNCI H2266.1794.500Details
BioGPS NCI60209837_atNCI H235.6204.500Details
BioGPS NCI60209837_atNCI H322M2.7784.500Details
BioGPS NCI60209837_atNCVADR RES3.7524.500Details
BioGPS NCI60209837_atOVCAR34.1264.500Details
BioGPS NCI60209837_atOVCAR44.0504.500Details
BioGPS NCI60209837_atOVCAR52.7554.500Details
BioGPS NCI60209837_atOVCAR83.6634.500Details
BioGPS NCI60209837_atPANC14.9284.500Details
BioGPS NCI60209837_atRL74.1174.500Details
BioGPS NCI60209837_atRPMI 82264.0624.500Details
BioGPS NCI60209837_atRS118464.1144.500Details
BioGPS NCI60209837_atRXF3934.0464.500Details
BioGPS NCI60209837_atSAOS24.0074.500Details
BioGPS NCI60209837_atSF2684.1844.500Details
BioGPS NCI60209837_atSF2954.0204.500Details
BioGPS NCI60209837_atSF5393.7574.500Details
BioGPS NCI60209837_atSHSYSY+RA8.0184.500Details
BioGPS NCI60209837_atSHSYSY-RA6.8614.500Details
BioGPS NCI60209837_atSKMEL24.0594.500Details
BioGPS NCI60209837_atSKMEL284.0644.500Details
BioGPS NCI60209837_atSKMEL53.9934.500Details
BioGPS NCI60209837_atSKOV34.0804.500Details
BioGPS NCI60209837_atSN12C4.5514.500Details
BioGPS NCI60209837_atSNB194.3674.500Details
BioGPS NCI60209837_atSNB754.0544.500Details
BioGPS NCI60209837_atSR4.0904.500Details
BioGPS NCI60209837_atSW6204.4034.500Details
BioGPS NCI60209837_atT243.5214.500Details
BioGPS NCI60209837_atT3M44.1044.500Details
BioGPS NCI60209837_atTK103.9504.500Details
BioGPS NCI60209837_atU1184.0324.500Details
BioGPS NCI60209837_atU1386.4584.500Details
BioGPS NCI60209837_atU20S4.0464.500Details
BioGPS NCI60209837_atU2513.6814.500Details
BioGPS NCI60209837_atU873.8524.500Details
BioGPS NCI60209837_atUACC2574.0074.500Details
BioGPS NCI60209837_atUACC624.0794.500Details
BioGPS NCI60209837_atUO316.7824.500Details
BioGPS NCI60209837_atZR75_14.1284.500Details
BioGPS NCI60209837_atastrocytes4.1174.500Details
BioGPS NCI60209837_athuh-74.1444.500Details