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Gene ID: 10717 | AP4B1 Antibody Resource


AP4B1 Antibody Resource
Gene Full Name: 
adaptor-related protein complex 4, beta 1 subunit
Uniprot: 
Q9Y6B7
Protein Name: 
AP-4 complex subunit beta-1
Nucleotide: 
NM_001253853
Alias: 
CPSQ5;SPG47;BETA-4;
Ensembl: 
ENSG00000134262
Location: 
1p13.2
HPRD: 
06259
NCBI Gene: 
10717
MIM: 
607245

Summary: 
This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Function: 
Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.
Subcellular location: 
Golgi apparatus › trans-Golgi network. Membrane › coated pit. Note: Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.
PTM: 
Disease: 
Cerebral palsy, spastic quadriplegic 5 (CPSQ5) [MIM:614066]: A neurodevelopmental disorder characterized by neonatal hypotonia that progresses to hypertonia and spasticity, and severe mental retardation with poor or absent speech development. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB12706 AP4B1 antibody - center region (OAAB12706) Human WB 400ul $289 Details
Polyclonal Antibody ARP68540_P050 AP4B1 Antibody - C-terminal region (ARP68540_P050) Human WB 50ug $289 Details

Show all AP4B1 antibodies


Product Images
AP4B1 Antibody - C-terminal region (ARP68540_P050) in Human 293T cells using Western Blot

Sample Type: Human 293T

AP4B1 antibody - center region (OAAB12706) in HepG2 cells using Western Blot

Sample Type: HepG2


AP4B1 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP68540 Bovine AP4B1 antibody; Bos taurus AP4B1 antibody F6PZ41 93.0%
ARP68539 Bovine AP4B1 antibody; Bos taurus AP4B1 antibody F6PZ41 86.0%
ARP68540 Cat AP4B1 antibody; Felis catus AP4B1 antibody M3WB21 100.0%
ARP68539 Cat AP4B1 antibody; Felis catus AP4B1 antibody M3WB21 93.0%
ARP68539 Chimpanzee AP4B1 antibody; Pan troglodytes AP4B1 antibody H2PZP9 100.0%
ARP68540 Chimpanzee AP4B1 antibody; Pan troglodytes AP4B1 antibody H2PZP9 100.0%
ARP68539 Dog AP4B1 antibody; Canis familiaris AP4B1 antibody F1PTH0 92.0%
ARP68540 Dog AP4B1 antibody; Canis familiaris AP4B1 antibody F1PTH0 86.0%
ARP68539 European domestic ferret AP4B1 antibody; Mustela putorius furo AP4B1 antibody M3Y1U6 93.0%
ARP68540 European domestic ferret AP4B1 antibody; Mustela putorius furo AP4B1 antibody M3Y1U6 86.0%
ARP68539 Giant panda AP4B1 antibody; Ailuropoda melanoleuca AP4B1 antibody D2H8V9 93.0%
ARP68540 Giant panda AP4B1 antibody; Ailuropoda melanoleuca AP4B1 antibody D2H8V9 79.0%
ARP68540 Horse AP4B1 antibody; Equus caballus AP4B1 antibody F6YPY8 93.0%
ARP68539 Horse AP4B1 antibody; Equus caballus AP4B1 antibody F6YPY8 92.0%
ARP68539 Human AP4B1 antibody; Homo sapiens AP4B1 antibody B1ALD0 100.0%
ARP68540 Human AP4B1 antibody; Homo sapiens AP4B1 antibody B1ALD0 100.0%
ARP68539 Human AP4B1 antibody; Homo sapiens AP4B1 antibody Q9Y6B7 100.0%
ARP68540 Human AP4B1 antibody; Homo sapiens AP4B1 antibody Q9Y6B7 100.0%
ARP68540 Northern white-cheeked gibbon AP4B1 antibody; Nomascus leucogenys AP4B1 antibody G1QX99 100.0%
ARP68539 Northern white-cheeked gibbon AP4B1 antibody; Nomascus leucogenys AP4B1 antibody G1QX99 93.0%
ARP68539 Pig AP4B1 antibody; Sus scrofa AP4B1 antibody F1SBR2 86.0%
ARP68540 Pig AP4B1 antibody; Sus scrofa AP4B1 antibody F1SBR2 86.0%
ARP68539 Rabbit AP4B1 antibody; Oryctolagus cuniculus AP4B1 antibody G1SKD8 93.0%
ARP68540 Rabbit AP4B1 antibody; Oryctolagus cuniculus AP4B1 antibody G1SKD8 79.0%
ARP68539 Rat AP4B1 antibody; Rattus norvegicus AP4B1 antibody D4AD35 83.0%
ARP68539 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody F7CS25 100.0%
ARP68539 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody F7H7N5 100.0%
ARP68539 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody G7MIJ3 100.0%
ARP68540 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody F7CS25 86.0%
ARP68540 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody F7H7N5 86.0%
ARP68540 Rhesus macaque AP4B1 antibody; Macaca mulatta AP4B1 antibody G7MIJ3 86.0%
ARP68539 Small-eared galago AP4B1 antibody; Otolemur garnettii AP4B1 antibody H0XUA0 86.0%
ARP68540 Small-eared galago AP4B1 antibody; Otolemur garnettii AP4B1 antibody H0XUA0 86.0%
ARP68539 Sumatran orangutan AP4B1 antibody; Pongo abelii AP4B1 antibody H2N6B3 100.0%
ARP68540 Sumatran orangutan AP4B1 antibody; Pongo abelii AP4B1 antibody H2N6B3 100.0%
ARP68539 Thirteen-lined ground squirrel AP4B1 antibody; Spermophilus tridecemlineatus AP4B1 antibody I3MNE3 93.0%
ARP68540 Thirteen-lined ground squirrel AP4B1 antibody; Spermophilus tridecemlineatus AP4B1 antibody I3MNE3 79.0%
ARP68540 White-tufted-ear marmoset AP4B1 antibody; Callithrix jacchus AP4B1 antibody F6XLI4 100.0%
ARP68540 White-tufted-ear marmoset AP4B1 antibody; Callithrix jacchus AP4B1 antibody F7D2X7 100.0%
ARP68539 White-tufted-ear marmoset AP4B1 antibody; Callithrix jacchus AP4B1 antibody F6XLI4 93.0%
ARP68539 White-tufted-ear marmoset AP4B1 antibody; Callithrix jacchus AP4B1 antibody F7D2X7 93.0%

Tissue & Cell Line Gene Expression Data