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Gene ID: 118429 | ANTXR2 Antibody Resource


ANTXR2 Antibody Resource
Gene Full Name: 
anthrax toxin receptor 2
Uniprot: 
P58335
Protein Name: 
anthrax toxin receptor 2
Nucleotide: 
NM_058172
Alias: 
HFS;ISH;JHF;CMG2;CMG-2;
Ensembl: 
ENSG00000163297
Location: 
4q21.21
HPRD: 
07452
NCBI Gene: 
118429
MIM: 
608041

Summary: 
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Function: 
Necessary for cellular interactions with laminin and the extracellular matrix.
Subcellular location: 
Isoform 1: Cell membrane; Single-pass type I membrane protein. Note: Expressed at the cell surface.Isoform 2: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note: Expressed predominantly within the endoplasmic reticulum and not at the plasma membrane.Isoform 3: Secreted.
PTM: 
Disulfide bond;
Disease: 
Hyaline fibromatosis syndrome (HFS) [MIM:228600]: An autosomal recessive syndrome characterized by abnormal growth of hyalinized fibrous tissue usually affecting subcutaneous regions on the scalp, ears, neck, face, hands, and feet. The lesions appear as pearly papules or fleshy nodules. Additional features include gingival hypertrophy, progressive joint contractures resulting in severe limitation of mobility, osteopenia, and osteoporosis. Disease severity is variable. Some individuals manifest symptoms in infancy and have additional visceral or systemic involvement. Hyaline deposits in multiple organs, recurrent infections and intractable diarrhea often lead to early death. Surviving children may suffer from severely reduced mobility due to joint contractures. Other patients have later onset of a milder disorder affecting only the face and digits. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP50242_P050 Antxr2 antibody - N-terminal region (ARP50242_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit WB 50ug $289 Details
Polyclonal Antibody OAEB01392 Goat Anti-ANTXR2 / CMG2 Antibody (OAEB01392) Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody ARP50241_P050 ANTXR2 Antibody - N-terminal region (ARP50241_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish WB 50ug $289 Details

Show all ANTXR2 antibodies


Product Images
ANTXR2 Antibody - N-terminal region (ARP50241_P050) in Human DU145 cells using Western Blot

Sample Type: Human DU145

Antxr2 antibody - N-terminal region (ARP50242_P050) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver

Goat Anti-ANTXR2 / CMG2 Antibody (OAEB01392) in Mouse Kidney cells using Western Blot

Sample Type: Mouse Kidney


ANTXR2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP50241 African elephant ANTXR2 antibody; Loxodonta africana ANTXR2 antibody G3SSX2 100.0%
ARP50242 African elephant ANTXR2 antibody; Loxodonta africana ANTXR2 antibody G3SSX2 100.0%
ARP50241 African elephant ANTXR2 antibody; Loxodonta africana ANTXR2 antibody G3UFW4 100.0%
ARP50242 African elephant ANTXR2 antibody; Loxodonta africana ANTXR2 antibody G3UFW4 100.0%
ARP50241 Bovine ANTXR2 antibody; Bos taurus ANTXR2 antibody Q08DG9 100.0%
ARP50242 Bovine ANTXR2 antibody; Bos taurus ANTXR2 antibody Q08DG9 100.0%
ARP41238 Bovine ANTXR2 antibody; Bos taurus ANTXR2 antibody Q08DG9 91.0%
ARP50241 Cat ANTXR2 antibody; Felis catus ANTXR2 antibody M3WP21 100.0%
ARP50242 Cat ANTXR2 antibody; Felis catus ANTXR2 antibody M3WP21 100.0%
ARP50241 Chimpanzee ANTXR2 antibody; Pan troglodytes ANTXR2 antibody H2QPS0 100.0%
ARP50242 Chimpanzee ANTXR2 antibody; Pan troglodytes ANTXR2 antibody H2QPS0 100.0%
ARP50241 Chimpanzee ANTXR2 antibody; Pan troglodytes ANTXR2 antibody K7B588 100.0%
ARP50242 Chimpanzee ANTXR2 antibody; Pan troglodytes ANTXR2 antibody K7B588 100.0%
ARP50241 Chinese softshell turtle ANTXR2 antibody; Pelodiscus sinensis ANTXR2 antibody K7GIM0 86.0%
ARP50241 Chinese softshell turtle ANTXR2 antibody; Pelodiscus sinensis ANTXR2 antibody K7GIM9 86.0%
ARP50242 Chinese softshell turtle ANTXR2 antibody; Pelodiscus sinensis ANTXR2 antibody K7GIM0 79.0%
ARP50242 Chinese softshell turtle ANTXR2 antibody; Pelodiscus sinensis ANTXR2 antibody K7GIM9 79.0%
ARP50241 Dog ANTXR2 antibody; Canis familiaris ANTXR2 antibody E2R0J4 100.0%
ARP50242 Dog ANTXR2 antibody; Canis familiaris ANTXR2 antibody E2R0J4 100.0%
ARP50241 Domestic duck ANTXR2 antibody; Anas platyrhynchos ANTXR2 antibody U3J4S5 79.0%
ARP50241 European domestic ferret ANTXR2 antibody; Mustela putorius furo ANTXR2 antibody M3Y5H2 100.0%
ARP50242 European domestic ferret ANTXR2 antibody; Mustela putorius furo ANTXR2 antibody M3Y5H2 100.0%
ARP50241 Giant panda ANTXR2 antibody; Ailuropoda melanoleuca ANTXR2 antibody G1LFC0 100.0%
ARP50242 Giant panda ANTXR2 antibody; Ailuropoda melanoleuca ANTXR2 antibody G1LFC0 100.0%
ARP50241 Gray short-tailed opossum ANTXR2 antibody; Monodelphis domestica ANTXR2 antibody F6S811 93.0%
ARP50242 Gray short-tailed opossum ANTXR2 antibody; Monodelphis domestica ANTXR2 antibody F6S811 86.0%
ARP50242 Horse ANTXR2 antibody; Equus caballus ANTXR2 antibody F7AN24 100.0%
ARP50241 Horse ANTXR2 antibody; Equus caballus ANTXR2 antibody F7AN24 93.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody A4FUA5 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody A4FUA5 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-2 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-2 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-3 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-3 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-4 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335-4 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody P58335 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody Q32Q26 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody Q32Q26 100.0%
ARP50241 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody J3KPY9 100.0%
ARP50242 Human ANTXR2 antibody; Homo sapiens ANTXR2 antibody J3KPY9 100.0%
ARP50241 Mouse ANTXR2 antibody; Mus musculus ANTXR2 antibody Q3TCL6 100.0%
ARP50242 Mouse ANTXR2 antibody; Mus musculus ANTXR2 antibody Q3TCL6 100.0%
ARP50241 Mouse ANTXR2 antibody; Mus musculus ANTXR2 antibody Q6DFX2 100.0%
ARP50242 Mouse ANTXR2 antibody; Mus musculus ANTXR2 antibody Q6DFX2 100.0%
ARP50241 Northern white-cheeked gibbon ANTXR2 antibody; Nomascus leucogenys ANTXR2 antibody G1RAV3 100.0%
ARP50242 Northern white-cheeked gibbon ANTXR2 antibody; Nomascus leucogenys ANTXR2 antibody G1RAV3 100.0%
ARP50241 Pig ANTXR2 antibody; Sus scrofa ANTXR2 antibody K9J4T3 100.0%
ARP50242 Pig ANTXR2 antibody; Sus scrofa ANTXR2 antibody K9J4T3 100.0%
ARP50241 Pig ANTXR2 antibody; Sus scrofa ANTXR2 antibody F1RVC2 100.0%
ARP50242 Pig ANTXR2 antibody; Sus scrofa ANTXR2 antibody F1RVC2 100.0%
ARP50241 Rabbit ANTXR2 antibody; Oryctolagus cuniculus ANTXR2 antibody G1U3Y6 100.0%
ARP50242 Rabbit ANTXR2 antibody; Oryctolagus cuniculus ANTXR2 antibody G1U3Y6 93.0%
ARP50241 Rat ANTXR2 antibody; Rattus norvegicus ANTXR2 antibody F1LT78 100.0%
ARP50242 Rat ANTXR2 antibody; Rattus norvegicus ANTXR2 antibody F1LT78 100.0%
ARP50241 Rat ANTXR2 antibody; Rattus norvegicus ANTXR2 antibody Q00IM8 100.0%
ARP50242 Rat ANTXR2 antibody; Rattus norvegicus ANTXR2 antibody Q00IM8 100.0%
ARP50241 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH39 100.0%
ARP50242 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH39 100.0%
ARP50241 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH50 100.0%
ARP50242 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH50 100.0%
ARP50241 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH69 100.0%
ARP50242 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody F7EH69 100.0%
ARP50241 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody I2CUV0 100.0%
ARP50242 Rhesus macaque ANTXR2 antibody; Macaca mulatta ANTXR2 antibody I2CUV0 100.0%
ARP50241 Small-eared galago ANTXR2 antibody; Otolemur garnettii ANTXR2 antibody H0X202 100.0%
ARP50242 Small-eared galago ANTXR2 antibody; Otolemur garnettii ANTXR2 antibody H0X202 100.0%
ARP50241 Sumatran orangutan ANTXR2 antibody; Pongo abelii ANTXR2 antibody H2PDQ8 100.0%
ARP50242 Sumatran orangutan ANTXR2 antibody; Pongo abelii ANTXR2 antibody H2PDQ8 100.0%
ARP50241 Tasmanian devil ANTXR2 antibody; Sarcophilus harrisii ANTXR2 antibody G3X1V0 86.0%
ARP50242 Tasmanian devil ANTXR2 antibody; Sarcophilus harrisii ANTXR2 antibody G3X1V0 79.0%
ARP50241 Thirteen-lined ground squirrel ANTXR2 antibody; Spermophilus tridecemlineatus ANTXR2 antibody I3NHS0 100.0%
ARP50242 Thirteen-lined ground squirrel ANTXR2 antibody; Spermophilus tridecemlineatus ANTXR2 antibody I3NHS0 100.0%
ARP50241 Western clawed frog ANTXR2 antibody; Xenopus tropicalis ANTXR2 antibody B2GUC8 86.0%
ARP50241 Western clawed frog ANTXR2 antibody; Xenopus tropicalis ANTXR2 antibody F6SXU7 86.0%
ARP50241 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7BK75 100.0%
ARP50242 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7BK75 100.0%
ARP50241 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7DCM3 100.0%
ARP50242 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7DCM3 100.0%
ARP50241 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7DSV6 100.0%
ARP50242 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody F7DSV6 100.0%
ARP50241 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody U3CVR5 100.0%
ARP50242 White-tufted-ear marmoset ANTXR2 antibody; Callithrix jacchus ANTXR2 antibody U3CVR5 100.0%
ARP50241 Zebra finch ANTXR2 antibody; Taeniopygia guttata ANTXR2 antibody H0YTG0 93.0%
ARP50242 Zebra finch ANTXR2 antibody; Taeniopygia guttata ANTXR2 antibody H0YTG0 79.0%

Tissue & Cell Line Gene Expression Data