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Gene ID: 203859 | ANO5 Antibody Resource


ANO5 Antibody Resource
Gene Full Name: 
anoctamin 5
Uniprot: 
Q75V66
Protein Name: 
anoctamin-5
Nucleotide: 
XM_005252822
Alias: 
GDD1;LGMD2L;TMEM16E;
Ensembl: 
ENSG00000171714
Location: 
11p14.3
HPRD: 
10558
NCBI Gene: 
203859
MIM: 
608662

Summary: 
This gene encodes a member of the anoctamin family of transmembrane proteins. The encoded protein is likely a calcium activated chloride channel. Mutations in this gene have been associated with gnathodiaphyseal dysplasia. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2009]
Function: 
Does not exhibit calcium-activated chloride channel (CaCC) activity.
Subcellular location: 
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane. Note: Colocalized with CALR/calreticulin. Shows an intracellular localization according to .
PTM: 
Glycoprotein;
Disease: 
Gnathodiaphyseal dysplasia (GDD) [MIM:166260]: Rare skeletal syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbone. Patients experience frequent bone fractures caused by trivial accidents in childhood; however the fractures heal normally without bone deformity. The jaw lesions replace the tooth-bearing segments of the maxilla and mandible with fibrous connective tissues, including various amounts of cementum-like calcified mass, sometimes causing facial deformities. Patients also have a propensity for jaw infection and often suffer from purulent osteomyelitis-like symptoms, such as swelling of and pus discharge from the gums, mobility of the teeth, insufficient healing after tooth extraction and exposure of the lesions into the oral cavity. Note: The disease is caused by mutations affecting the gene represented in this entry. Limb-girdle muscular dystrophy 2L (LGMD2L) [MIM:611307]: An autosomal recessive degenerative myopathy characterized by proximal weakness, weakness of the hip and shoulder girdles and prominent asymmetrical quadriceps femoris and biceps brachii atrophy. Note: The disease is caused by mutations affecting the gene represented in this entry. Miyoshi muscular dystrophy 3 (MMD3) [MIM:613319]: A late-onset muscular dystrophy characterized by distal muscle weakness of the lower limbs, calf muscle discomfort and weakness, quadriceps atrophy. Muscle weakness and atrophy may be asymmetric. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB05173 ANO5 antibody - C-terminal region (OAAB05173) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP66513_P050 ANO5 Antibody (ARP66513_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP66514_P050 ANO5 Antibody (ARP66514_P050) Polyclonal Not tested 50 ug $125 Details

Show all ANO5 antibodies


Product Images
ANO5 antibody - C-terminal region (OAAB05173) in human lymph cells using Immunohistochemistry

Sample Type: human lymph

ANO5 antibody - C-terminal region (OAAB05173) in mouse spleen cells using Western Blot

Sample Type: mouse spleen


ANO5 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP66514 African elephant ANO5 antibody; Loxodonta africana ANO5 antibody G3UK98 85.0%
ARP66513 Bovine ANO5 antibody; Bos taurus ANO5 antibody F1MPC2 86.0%
ARP66514 Cat ANO5 antibody; Felis catus ANO5 antibody M3WYP5 93.0%
ARP66513 Cat ANO5 antibody; Felis catus ANO5 antibody M3WYP5 86.0%
ARP66513 Chimpanzee ANO5 antibody; Pan troglodytes ANO5 antibody H2Q3B1 100.0%
ARP66514 Chimpanzee ANO5 antibody; Pan troglodytes ANO5 antibody H2Q3B1 100.0%
ARP66514 Dog ANO5 antibody; Canis familiaris ANO5 antibody F1PEC2 92.0%
ARP66514 Dog ANO5 antibody; Canis familiaris ANO5 antibody F1PED0 92.0%
ARP66513 Dog ANO5 antibody; Canis familiaris ANO5 antibody F1PEC2 86.0%
ARP66513 Dog ANO5 antibody; Canis familiaris ANO5 antibody F1PED0 86.0%
ARP66513 Duckbill platypus ANO5 antibody; Ornithorhynchus anatinus ANO5 antibody F6TYB8 79.0%
ARP66513 European domestic ferret ANO5 antibody; Mustela putorius furo ANO5 antibody M3YR82 93.0%
ARP66514 European domestic ferret ANO5 antibody; Mustela putorius furo ANO5 antibody M3YR82 85.0%
ARP66513 Gray short-tailed opossum ANO5 antibody; Monodelphis domestica ANO5 antibody F7CR53 86.0%
ARP66514 Horse ANO5 antibody; Equus caballus ANO5 antibody F6S8P9 92.0%
ARP66513 Horse ANO5 antibody; Equus caballus ANO5 antibody F6S8P9 86.0%
ARP66513 Human ANO5 antibody; Homo sapiens ANO5 antibody Q75V66 100.0%
ARP66514 Human ANO5 antibody; Homo sapiens ANO5 antibody Q75V66 100.0%
ARP66513 Northern white-cheeked gibbon ANO5 antibody; Nomascus leucogenys ANO5 antibody G1S826 100.0%
ARP66514 Northern white-cheeked gibbon ANO5 antibody; Nomascus leucogenys ANO5 antibody G1S826 100.0%
ARP66514 Pig ANO5 antibody; Sus scrofa ANO5 antibody F1SFZ1 92.0%
ARP66514 Pig ANO5 antibody; Sus scrofa ANO5 antibody I3LFE1 92.0%
ARP66513 Pig ANO5 antibody; Sus scrofa ANO5 antibody F1SFZ1 86.0%
ARP66513 Pig ANO5 antibody; Sus scrofa ANO5 antibody I3LFE1 86.0%
ARP66513 Rabbit ANO5 antibody; Oryctolagus cuniculus ANO5 antibody G1SCV2 100.0%
ARP66514 Rabbit ANO5 antibody; Oryctolagus cuniculus ANO5 antibody G1SCV2 93.0%
ARP66513 Rhesus macaque ANO5 antibody; Macaca mulatta ANO5 antibody F7HQS3 100.0%
ARP66514 Rhesus macaque ANO5 antibody; Macaca mulatta ANO5 antibody F7HQS3 100.0%
ARP66513 Rhesus macaque ANO5 antibody; Macaca mulatta ANO5 antibody H9FEV2 100.0%
ARP66514 Rhesus macaque ANO5 antibody; Macaca mulatta ANO5 antibody H9FEV2 100.0%
ARP66514 Small-eared galago ANO5 antibody; Otolemur garnettii ANO5 antibody H0WNM0 92.0%
ARP66513 Small-eared galago ANO5 antibody; Otolemur garnettii ANO5 antibody H0WNM0 86.0%
ARP66513 Sumatran orangutan ANO5 antibody; Pongo abelii ANO5 antibody H2NDW1 100.0%
ARP66514 Sumatran orangutan ANO5 antibody; Pongo abelii ANO5 antibody H2NDW1 100.0%
ARP53917 Sumatran orangutan ANO5 antibody; Pongo abelii ANO5 antibody H2NDW1 79.0%
ARP66513 Tasmanian devil ANO5 antibody; Sarcophilus harrisii ANO5 antibody G3WGN2 86.0%
ARP66513 Tasmanian devil ANO5 antibody; Sarcophilus harrisii ANO5 antibody G3WGN3 86.0%
ARP66513 Thirteen-lined ground squirrel ANO5 antibody; Spermophilus tridecemlineatus ANO5 antibody I3MP31 100.0%
ARP66513 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7EUG3 100.0%
ARP66514 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7EUG3 100.0%
ARP66513 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7FKV4 100.0%
ARP66514 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7FKV4 100.0%
ARP66513 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7FZC9 100.0%
ARP66514 White-tufted-ear marmoset ANO5 antibody; Callithrix jacchus ANO5 antibody F7FZC9 100.0%
ARP44761 Zebra finch ANO5 antibody; Taeniopygia guttata ANO5 antibody H0Z2A5 89.0%

Tissue & Cell Line Gene Expression Data