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Gene ID: 56172 | ANKH Antibody Resource


ANKH Antibody Resource
Gene Full Name: 
ANKH inorganic pyrophosphate transport regulator
Uniprot: 
Q9HCJ1
Protein Name: 
progressive ankylosis protein homolog
Nucleotide: 
NM_054027
Alias: 
ANK;CMDJ;HANK;MANK;CCAL2;CPPDD;
Ensembl: 
ENSG00000154122
Location: 
5p15.1
HPRD: 
05509
NCBI Gene: 
56172
MIM: 
605145

Summary: 
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]
Function: 
Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter.
Subcellular location: 
Membrane; Multi-pass membrane protein Probable.
PTM: 
Disease: 
Chondrocalcinosis 2 (CCAL2) [MIM:118600]: Chondrocalcinosis is a common cause of joint pain and arthritis caused by calcium deposition in articular cartilage and the presence of calcium hypophosphate crystals in synovial fluid, cartilage and periarticular soft tissue. CCAL2 inheritance is autosomal dominant. Note: The disease is caused by mutations affecting the gene represented in this entry. Craniometaphyseal dysplasia, autosomal dominant (CMDD) [MIM:123000]: An osteochondrodysplasia characterized by hyperostosis and sclerosis of the craniofacial bones associated with abnormal modeling of the metaphyses. Sclerosis of the skull may lead to asymmetry of the mandible, as well as to cranial nerve compression, that may finally result in hearing loss and facial palsy. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP50237_P050 ANKH antibody - N-terminal region (ARP50237_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB06341 ANKH antibody - C-terminal region (OAAB06341) Human; Mouse WB, FC, IHC 400ul $289 Details

Show all ANKH antibodies


Product Images
ANKH antibody - N-terminal region (ARP50237_P050) in Human THP-1 cells using Western Blot

Sample Type: Human THP-1

ANKH antibody - C-terminal region (OAAB06341) in brain cells using Immunohistochemistry

Sample Type: brain

ANKH antibody - C-terminal region (OAAB06341) in K562 cells using Flow Cytometry

Sample Type: K562

ANKH antibody - C-terminal region (OAAB06341) in mouse cerebellum cells using Western Blot

Sample Type: mouse cerebellum


ANKH Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP50237 African clawed frog ANKH antibody; Xenopus laevis ANKH antibody P58367 86.0%
ARP50237 African clawed frog ANKH antibody; Xenopus laevis ANKH antibody Q6NS07 86.0%
ARP50237 African elephant ANKH antibody; Loxodonta africana ANKH antibody G3SR72 100.0%
ARP50237 Atlantic salmon ANKH antibody; Salmo salar ANKH antibody B5X5W7 86.0%
ARP50237 Bovine ANKH antibody; Bos taurus ANKH antibody A8E659 93.0%
ARP50237 Bovine ANKH antibody; Bos taurus ANKH antibody F1MAW1 93.0%
ARP50237 Chicken ANKH antibody; Gallus gallus ANKH antibody F1NNA3 100.0%
ARP50237 Chimpanzee ANKH antibody; Pan troglodytes ANKH antibody H2QQN8 100.0%
ARP50237 Chinese softshell turtle ANKH antibody; Pelodiscus sinensis ANKH antibody K7FYJ9 100.0%
ARP50237 Collared flycatcher ANKH antibody; Ficedula albicollis ANKH antibody U3JYG8 100.0%
ARP50237 Dog ANKH antibody; Canis familiaris ANKH antibody E2RRC7 100.0%
ARP50237 Domestic duck ANKH antibody; Anas platyrhynchos ANKH antibody U3IFS0 100.0%
ARP50237 Duckbill platypus ANKH antibody; Ornithorhynchus anatinus ANKH antibody F6TZU8 100.0%
ARP50237 European domestic ferret ANKH antibody; Mustela putorius furo ANKH antibody M3YI79 100.0%
ARP50237 European seabass ANKH antibody; Dicentrarchus labrax ANKH antibody E6ZJ63 93.0%
ARP50237 Giant panda ANKH antibody; Ailuropoda melanoleuca ANKH antibody G1LT81 100.0%
ARP50237 Gray short-tailed opossum ANKH antibody; Monodelphis domestica ANKH antibody F6Q5B1 93.0%
ARP50237 Horse ANKH antibody; Equus caballus ANKH antibody F7E3B8 93.0%
ARP50237 Human ANKH antibody; Homo sapiens ANKH antibody Q9HCJ1 100.0%
ARP50237 Mouse ANKH antibody; Mus musculus ANKH antibody Q9JHZ2 100.0%
ARP50237 Northern white-cheeked gibbon ANKH antibody; Nomascus leucogenys ANKH antibody G1RME8 100.0%
ARP50237 Pig ANKH antibody; Sus scrofa ANKH antibody F1SRN1 93.0%
ARP50237 Rabbit ANKH antibody; Oryctolagus cuniculus ANKH antibody G1T2I7 100.0%
ARP50237 Rat ANKH antibody; Rattus norvegicus ANKH antibody F1LN34 100.0%
ARP50237 Rat ANKH antibody; Rattus norvegicus ANKH antibody P58366 100.0%
ARP50237 Rhesus macaque ANKH antibody; Macaca mulatta ANKH antibody F6T3T0 100.0%
ARP50237 Small-eared galago ANKH antibody; Otolemur garnettii ANKH antibody H0WUN1 93.0%
ARP50237 Spotted green pufferfish ANKH antibody; Tetraodon nigroviridis ANKH antibody H3DIC6 86.0%
ARP50237 Spotted green pufferfish ANKH antibody; Tetraodon nigroviridis ANKH antibody P58369 86.0%
ARP44891 Spotted green pufferfish ANKH antibody; Tetraodon nigroviridis ANKH antibody H3DIC6 82.0%
ARP50237 Sumatran orangutan ANKH antibody; Pongo abelii ANKH antibody H2PF77 100.0%
ARP50237 Tasmanian devil ANKH antibody; Sarcophilus harrisii ANKH antibody G3WEV0 93.0%
ARP50237 Thirteen-lined ground squirrel ANKH antibody; Spermophilus tridecemlineatus ANKH antibody I3MNA6 100.0%
ARP50237 Western clawed frog ANKH antibody; Xenopus tropicalis ANKH antibody F6S3Z5 86.0%
ARP50237 White-tufted-ear marmoset ANKH antibody; Callithrix jacchus ANKH antibody F7D3S3 100.0%
ARP50237 Zebra finch ANKH antibody; Taeniopygia guttata ANKH antibody H0ZAN4 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas220076_at721_B_lymphoblasts7.2007.160Details
BioGPS Gene Atlas220076_atAdipocyte6.2507.160Details
BioGPS Gene Atlas220076_atAdrenalCortex8.0507.160Details
BioGPS Gene Atlas220076_atAdrenalgland5.8007.160Details
BioGPS Gene Atlas220076_atAmygdala7.8007.160Details
BioGPS Gene Atlas220076_atAppendix7.3007.160Details
BioGPS Gene Atlas220076_atAtrioventricularNode6.1507.160Details
BioGPS Gene Atlas220076_atBDCA4+_DentriticCells6.6007.160Details
BioGPS Gene Atlas220076_atBonemarrow7.1507.160Details
BioGPS Gene Atlas220076_atBronchialEpithelialCells6.2007.160Details
BioGPS Gene Atlas220076_atCD105+_Endothelial6.4007.160Details
BioGPS Gene Atlas220076_atCD14+_Monocytes6.9507.160Details
BioGPS Gene Atlas220076_atCD19+_BCells(neg._sel.)6.5507.160Details
BioGPS Gene Atlas220076_atCD33+_Myeloid7.8507.160Details
BioGPS Gene Atlas220076_atCD34+7.8007.160Details
BioGPS Gene Atlas220076_atCD4+_Tcells7.3007.160Details
BioGPS Gene Atlas220076_atCD56+_NKCells7.8507.160Details
BioGPS Gene Atlas220076_atCD71+_EarlyErythroid6.7507.160Details
BioGPS Gene Atlas220076_atCD8+_Tcells6.2007.160Details
BioGPS Gene Atlas220076_atCardiacMyocytes10.6007.160Details
BioGPS Gene Atlas220076_atCaudatenucleus5.8507.160Details
BioGPS Gene Atlas220076_atCerebellum7.6007.160Details
BioGPS Gene Atlas220076_atCerebellumPeduncles20.7507.160Details
BioGPS Gene Atlas220076_atCiliaryGanglion5.5507.160Details
BioGPS Gene Atlas220076_atCingulateCortex8.1007.160Details
BioGPS Gene Atlas220076_atColorectaladenocarcinoma6.3507.160Details
BioGPS Gene Atlas220076_atDorsalRootGanglion6.6507.160Details
BioGPS Gene Atlas220076_atFetalThyroid7.1507.160Details
BioGPS Gene Atlas220076_atFetalbrain11.0007.160Details
BioGPS Gene Atlas220076_atFetalliver5.6507.160Details
BioGPS Gene Atlas220076_atFetallung5.0507.160Details
BioGPS Gene Atlas220076_atGlobusPallidus6.5007.160Details
BioGPS Gene Atlas220076_atHeart10.0507.160Details
BioGPS Gene Atlas220076_atHypothalamus8.1507.160Details
BioGPS Gene Atlas220076_atKidney5.8007.160Details
BioGPS Gene Atlas220076_atLeukemia_chronicMyelogenousK-5625.8007.160Details
BioGPS Gene Atlas220076_atLeukemia_promyelocytic-HL-605.6507.160Details
BioGPS Gene Atlas220076_atLeukemialymphoblastic(MOLT-4)5.1007.160Details
BioGPS Gene Atlas220076_atLiver10.2007.160Details
BioGPS Gene Atlas220076_atLung7.3007.160Details
BioGPS Gene Atlas220076_atLymphnode5.3507.160Details
BioGPS Gene Atlas220076_atLymphoma_burkitts(Daudi)8.4007.160Details
BioGPS Gene Atlas220076_atLymphoma_burkitts(Raji)9.8007.160Details
BioGPS Gene Atlas220076_atMedullaOblongata6.0507.160Details
BioGPS Gene Atlas220076_atOccipitalLobe6.5007.160Details
BioGPS Gene Atlas220076_atOlfactoryBulb5.1007.160Details
BioGPS Gene Atlas220076_atOvary5.5007.160Details
BioGPS Gene Atlas220076_atPancreas5.4007.160Details
BioGPS Gene Atlas220076_atPancreaticIslet7.0007.160Details
BioGPS Gene Atlas220076_atParietalLobe7.5507.160Details
BioGPS Gene Atlas220076_atPituitary7.7007.160Details
BioGPS Gene Atlas220076_atPlacenta6.3507.160Details
BioGPS Gene Atlas220076_atPons6.4007.160Details
BioGPS Gene Atlas220076_atPrefrontalCortex12.1007.160Details
BioGPS Gene Atlas220076_atProstate9.5507.160Details
BioGPS Gene Atlas220076_atSalivarygland5.5007.160Details
BioGPS Gene Atlas220076_atSkeletalMuscle9.0007.160Details
BioGPS Gene Atlas220076_atSkin5.8007.160Details
BioGPS Gene Atlas220076_atSmoothMuscle7.2007.160Details
BioGPS Gene Atlas220076_atSpinalcord6.8007.160Details
BioGPS Gene Atlas220076_atSubthalamicNucleus6.3507.160Details
BioGPS Gene Atlas220076_atSuperiorCervicalGanglion9.0507.160Details
BioGPS Gene Atlas220076_atTemporalLobe6.0507.160Details
BioGPS Gene Atlas220076_atTestis5.4507.160Details
BioGPS Gene Atlas220076_atTestisGermCell5.1007.160Details
BioGPS Gene Atlas220076_atTestisIntersitial5.5007.160Details
BioGPS Gene Atlas220076_atTestisLeydigCell6.6507.160Details
BioGPS Gene Atlas220076_atTestisSeminiferousTubule5.5007.160Details
BioGPS Gene Atlas220076_atThalamus6.9007.160Details
BioGPS Gene Atlas220076_atThymus5.0507.160Details
BioGPS Gene Atlas220076_atThyroid8.1007.160Details
BioGPS Gene Atlas220076_atTongue7.5007.160Details
BioGPS Gene Atlas220076_atTonsil6.5007.160Details
BioGPS Gene Atlas220076_atTrachea5.4507.160Details
BioGPS Gene Atlas220076_atTrigeminalGanglion7.5507.160Details
BioGPS Gene Atlas220076_atUterus5.4007.160Details
BioGPS Gene Atlas220076_atUterusCorpus6.5007.160Details
BioGPS Gene Atlas220076_atWholeBlood7.0507.160Details
BioGPS Gene Atlas220076_atWholebrain5.4007.160Details
BioGPS Gene Atlas220076_atcolon6.5007.160Details
BioGPS Gene Atlas220076_atpineal_day8.3207.160Details
BioGPS Gene Atlas220076_atpineal_night7.9807.160Details
BioGPS Gene Atlas220076_atretina7.8507.160Details
BioGPS Gene Atlas220076_atsmall_intestine6.1507.160Details
BioGPS NCI60220076_at7866.8866.690Details
BioGPS NCI60220076_atA1725.8836.690Details
BioGPS NCI60220076_atA2046.4076.690Details
BioGPS NCI60220076_atA3616.6016.690Details
BioGPS NCI60220076_atA4986.4026.690Details
BioGPS NCI60220076_atA5496.6956.690Details
BioGPS NCI60220076_atACC38.0316.690Details
BioGPS NCI60220076_atACHN5.7096.690Details
BioGPS NCI60220076_atALVA317.4686.690Details
BioGPS NCI60220076_atCAKI17.1406.690Details
BioGPS NCI60220076_atCCRT CEM8.3206.690Details
BioGPS NCI60220076_atCOLO2056.5586.690Details
BioGPS NCI60220076_atDLD16.2526.690Details
BioGPS NCI60220076_atDU1455.9846.690Details
BioGPS NCI60220076_atEKVX5.9596.690Details
BioGPS NCI60220076_atGM1336.8286.690Details
BioGPS NCI60220076_atGM160014.1796.690Details
BioGPS NCI60220076_atGM23136.7016.690Details
BioGPS NCI60220076_atGM23456.4336.690Details
BioGPS NCI60220076_atGM24937.4846.690Details
BioGPS NCI60220076_atGM979.2626.690Details
BioGPS NCI60220076_atHCC29985.3546.690Details
BioGPS NCI60220076_atHCT1166.5256.690Details
BioGPS NCI60220076_atHCT155.8456.690Details
BioGPS NCI60220076_atHEK 293 T-rex6.9446.690Details
BioGPS NCI60220076_atHEK 293T6.3846.690Details
BioGPS NCI60220076_atHEK2936.6146.690Details
BioGPS NCI60220076_atHELA6.2856.690Details
BioGPS NCI60220076_atHEPG26.6186.690Details
BioGPS NCI60220076_atHL607.2796.690Details
BioGPS NCI60220076_atHOP626.5036.690Details
BioGPS NCI60220076_atHOP926.0916.690Details
BioGPS NCI60220076_atHS578T6.3956.690Details
BioGPS NCI60220076_atHSG5.9946.690Details
BioGPS NCI60220076_atHT10806.4906.690Details
BioGPS NCI60220076_atHT297.8716.690Details
BioGPS NCI60220076_atIGROV16.3026.690Details
BioGPS NCI60220076_atIOSE806.4346.690Details
BioGPS NCI60220076_atJURKAT6.4226.690Details
BioGPS NCI60220076_atK5627.7636.690Details
BioGPS NCI60220076_atKM127.1346.690Details
BioGPS NCI60220076_atLN185.6736.690Details
BioGPS NCI60220076_atLNCAP6.4756.690Details
BioGPS NCI60220076_atLOX IMVI6.3946.690Details
BioGPS NCI60220076_atM146.4816.690Details
BioGPS NCI60220076_atMALME 3M7.5196.690Details
BioGPS NCI60220076_atMCF76.1226.690Details
BioGPS NCI60220076_atMD MB2316.8426.690Details
BioGPS NCI60220076_atMDA MB4357.7506.690Details
BioGPS NCI60220076_atMOLT46.9016.690Details
BioGPS NCI60220076_atNCI 4606.7726.690Details
BioGPS NCI60220076_atNCI H2266.9046.690Details
BioGPS NCI60220076_atNCI H236.4306.690Details
BioGPS NCI60220076_atNCI H322M6.4016.690Details
BioGPS NCI60220076_atNCVADR RES6.2586.690Details
BioGPS NCI60220076_atOVCAR37.0026.690Details
BioGPS NCI60220076_atOVCAR46.3846.690Details
BioGPS NCI60220076_atOVCAR56.2036.690Details
BioGPS NCI60220076_atOVCAR86.1366.690Details
BioGPS NCI60220076_atPANC16.6056.690Details
BioGPS NCI60220076_atRL76.6936.690Details
BioGPS NCI60220076_atRPMI 82267.0056.690Details
BioGPS NCI60220076_atRS118467.2906.690Details
BioGPS NCI60220076_atRXF3936.4816.690Details
BioGPS NCI60220076_atSAOS26.5606.690Details
BioGPS NCI60220076_atSF2686.4146.690Details
BioGPS NCI60220076_atSF2956.0926.690Details
BioGPS NCI60220076_atSF5395.7976.690Details
BioGPS NCI60220076_atSHSYSY+RA6.0066.690Details
BioGPS NCI60220076_atSHSYSY-RA6.2846.690Details
BioGPS NCI60220076_atSKMEL26.4146.690Details
BioGPS NCI60220076_atSKMEL286.4906.690Details
BioGPS NCI60220076_atSKMEL55.9536.690Details
BioGPS NCI60220076_atSKOV37.0706.690Details
BioGPS NCI60220076_atSN12C6.3546.690Details
BioGPS NCI60220076_atSNB195.8476.690Details
BioGPS NCI60220076_atSNB756.2936.690Details
BioGPS NCI60220076_atSR6.7886.690Details
BioGPS NCI60220076_atSW6206.6306.690Details
BioGPS NCI60220076_atT246.7326.690Details
BioGPS NCI60220076_atT3M46.9746.690Details
BioGPS NCI60220076_atTK106.3706.690Details
BioGPS NCI60220076_atU1186.4556.690Details
BioGPS NCI60220076_atU1388.1556.690Details
BioGPS NCI60220076_atU20S6.2076.690Details
BioGPS NCI60220076_atU2516.2686.690Details
BioGPS NCI60220076_atU876.3776.690Details
BioGPS NCI60220076_atUACC2576.1336.690Details
BioGPS NCI60220076_atUACC626.6946.690Details
BioGPS NCI60220076_atUO316.0966.690Details
BioGPS NCI60220076_atZR75_17.0456.690Details
BioGPS NCI60220076_atastrocytes6.4876.690Details
BioGPS NCI60220076_athuh-76.8016.690Details