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Gene ID: 51129 | ANGPTL4 Antibody Resource


ANGPTL4 Antibody Resource
Gene Full Name: 
angiopoietin-like 4
Uniprot: 
Q9BY76
Protein Name: 
angiopoietin-related protein 4
Nucleotide: 
NM_139314
Alias: 
NL2;ARP4;FIAF;HARP;PGAR;HFARP;UNQ171;pp1158;ANGPTL2;
Ensembl: 
ENSG00000167772
Location: 
19p13.3
HPRD: 
16173
NCBI Gene: 
51129
MIM: 
605910

Summary: 
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013]
Function: 
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation .
Subcellular location: 
Secreted. Secreted › extracellular space › extracellular matrix. Note: The unprocessed form interacts with the extracellular matrix. This may constitute a dynamic reservoir, a regulatory mechanism of the bioavailability of ANGPTL4 .
PTM: 
Disulfide bond;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Protein OPPA00514 ANGPTL4 Human - Recombinant Human Angiopoietin-like Protein 4 (2ug) ELISA, WB 2ug $100 Details
Polyclonal Antibody OAEB00417 ANGPTL4 Antibody (OAEB00417) Mouse ELISA 0.1mg $229 Details
Polyclonal Antibody OAAB05799 ANGPTL4 antibody - center region (OAAB05799) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP61602_P050 ANGPTL4 Antibody (ARP61602_P050) Polyclonal Bovine, Dog, Goat, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details

Show all ANGPTL4 antibodies


Product Images
ANGPTL4 antibody - center region (OAAB05799) in Human Skeletal Muscle cells using Immunohistochemistry

Sample Type: Human Skeletal Muscle

ANGPTL4 antibody - center region (OAAB05799) in Mouse Liver cells using Western Blot

Sample Type: Mouse Liver


ANGPTL4 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP56799 Bovine ANGPTL4 antibody; Bos taurus ANGPTL4 antibody B2Z4B2 86.0%
ARP45702 Bovine ANGPTL4 antibody; Bos taurus ANGPTL4 antibody Q2KJ51 79.0%
ARP61602 Bovine ANGPTL4 antibody; Bos taurus ANGPTL4 antibody Q2KJ51 79.0%
ARP45702 Cat ANGPTL4 antibody; Felis catus ANGPTL4 antibody M3WM65 79.0%
ARP61602 Cat ANGPTL4 antibody; Felis catus ANGPTL4 antibody M3WM65 79.0%
ARP61602 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody H2QF83 100.0%
ARP61602 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody K7AXV2 100.0%
ARP61602 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody K7CLB7 100.0%
ARP45702 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody H2QF83 79.0%
ARP45702 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody K7AXV2 79.0%
ARP45702 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody K7CLB7 79.0%
ARP45702 Chimpanzee ANGPTL4 antibody; Pan troglodytes ANGPTL4 antibody K7CMD1 79.0%
ARP65602 Collared flycatcher ANGPTL4 antibody; Ficedula albicollis ANGPTL4 antibody U3KBC0 100.0%
ARP61602 Dog ANGPTL4 antibody; Canis familiaris ANGPTL4 antibody F1PLK4 86.0%
ARP45702 Dog ANGPTL4 antibody; Canis familiaris ANGPTL4 antibody F1PLK4 79.0%
ARP61602 European domestic ferret ANGPTL4 antibody; Mustela putorius furo ANGPTL4 antibody M3Y7A8 86.0%
ARP45702 European domestic ferret ANGPTL4 antibody; Mustela putorius furo ANGPTL4 antibody M3Y7A8 79.0%
ARP61602 Giant panda ANGPTL4 antibody; Ailuropoda melanoleuca ANGPTL4 antibody G1LE95 86.0%
ARP45702 Giant panda ANGPTL4 antibody; Ailuropoda melanoleuca ANGPTL4 antibody G1LE95 79.0%
ARP61602 Horse ANGPTL4 antibody; Equus caballus ANGPTL4 antibody F7A971 86.0%
ARP45702 Horse ANGPTL4 antibody; Equus caballus ANGPTL4 antibody F7A971 79.0%
ARP61602 Human ANGPTL4 antibody; Homo sapiens ANGPTL4 antibody F5H0I2 100.0%
ARP61602 Human ANGPTL4 antibody; Homo sapiens ANGPTL4 antibody Q9BY76 100.0%
ARP45702 Human ANGPTL4 antibody; Homo sapiens ANGPTL4 antibody F5H0I2 79.0%
ARP45702 Human ANGPTL4 antibody; Homo sapiens ANGPTL4 antibody Q9BY76-2 79.0%
ARP45702 Human ANGPTL4 antibody; Homo sapiens ANGPTL4 antibody Q9BY76 79.0%
ARP61602 Mouse ANGPTL4 antibody; Mus musculus ANGPTL4 antibody Q3UYS5 86.0%
ARP61602 Mouse ANGPTL4 antibody; Mus musculus ANGPTL4 antibody Q8CEZ7 86.0%
ARP61602 Mouse ANGPTL4 antibody; Mus musculus ANGPTL4 antibody Q9Z1P8 86.0%
ARP61602 Pig ANGPTL4 antibody; Sus scrofa ANGPTL4 antibody Q2TNK5 86.0%
ARP45702 Pig ANGPTL4 antibody; Sus scrofa ANGPTL4 antibody Q2TNK5 79.0%
ARP61602 Rabbit ANGPTL4 antibody; Oryctolagus cuniculus ANGPTL4 antibody G1TBZ2 86.0%
ARP61602 Rat ANGPTL4 antibody; Rattus norvegicus ANGPTL4 antibody Q6TMA8 86.0%
ARP61602 Rhesus macaque ANGPTL4 antibody; Macaca mulatta ANGPTL4 antibody F6YZG3 86.0%
ARP61602 Rhesus macaque ANGPTL4 antibody; Macaca mulatta ANGPTL4 antibody H9F2Y3 86.0%
ARP45702 Rhesus macaque ANGPTL4 antibody; Macaca mulatta ANGPTL4 antibody H9F2Y3 79.0%
ARP61602 Small-eared galago ANGPTL4 antibody; Otolemur garnettii ANGPTL4 antibody H0WMC5 86.0%
ARP61602 Sumatran orangutan ANGPTL4 antibody; Pongo abelii ANGPTL4 antibody H2NXE1 86.0%
ARP45702 Sumatran orangutan ANGPTL4 antibody; Pongo abelii ANGPTL4 antibody H2NXE1 79.0%
ARP61602 Thirteen-lined ground squirrel ANGPTL4 antibody; Spermophilus tridecemlineatus ANGPTL4 antibody I3MAY6 86.0%
ARP45702 Thirteen-lined ground squirrel ANGPTL4 antibody; Spermophilus tridecemlineatus ANGPTL4 antibody I3MAY6 79.0%
ARP42411 Western clawed frog ANGPTL4 antibody; Xenopus tropicalis ANGPTL4 antibody F6YHP2 79.0%
ARP42411 Western clawed frog ANGPTL4 antibody; Xenopus tropicalis ANGPTL4 antibody F6YHQ1 79.0%
ARP61602 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7C7F2 93.0%
ARP61602 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7F7W8 93.0%
ARP61602 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7IBB3 93.0%
ARP61602 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody U3F2U2 93.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7C7E3 79.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7C7F2 79.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7F7W8 79.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody F7IBB3 79.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody U3F2U2 79.0%
ARP45702 White-tufted-ear marmoset ANGPTL4 antibody; Callithrix jacchus ANGPTL4 antibody U3FU81 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas221009_s_at721_B_lymphoblasts6.5008.620Details
BioGPS Gene Atlas221009_s_atAdipocyte14.5508.620Details
BioGPS Gene Atlas221009_s_atAdrenalCortex19.4508.620Details
BioGPS Gene Atlas221009_s_atAdrenalgland5.2508.620Details
BioGPS Gene Atlas221009_s_atAmygdala5.9008.620Details
BioGPS Gene Atlas221009_s_atAppendix8.0508.620Details
BioGPS Gene Atlas221009_s_atAtrioventricularNode6.2508.620Details
BioGPS Gene Atlas221009_s_atBDCA4+_DentriticCells6.0008.620Details
BioGPS Gene Atlas221009_s_atBonemarrow6.2008.620Details
BioGPS Gene Atlas221009_s_atBronchialEpithelialCells25.8008.620Details
BioGPS Gene Atlas221009_s_atCD105+_Endothelial6.0008.620Details
BioGPS Gene Atlas221009_s_atCD14+_Monocytes6.1508.620Details
BioGPS Gene Atlas221009_s_atCD19+_BCells(neg._sel.)6.9508.620Details
BioGPS Gene Atlas221009_s_atCD33+_Myeloid7.2508.620Details
BioGPS Gene Atlas221009_s_atCD34+7.9508.620Details
BioGPS Gene Atlas221009_s_atCD4+_Tcells6.0508.620Details
BioGPS Gene Atlas221009_s_atCD56+_NKCells6.7008.620Details
BioGPS Gene Atlas221009_s_atCD71+_EarlyErythroid5.7008.620Details
BioGPS Gene Atlas221009_s_atCD8+_Tcells5.4008.620Details
BioGPS Gene Atlas221009_s_atCardiacMyocytes11.3008.620Details
BioGPS Gene Atlas221009_s_atCaudatenucleus6.0008.620Details
BioGPS Gene Atlas221009_s_atCerebellum4.8008.620Details
BioGPS Gene Atlas221009_s_atCerebellumPeduncles8.1008.620Details
BioGPS Gene Atlas221009_s_atCiliaryGanglion13.8508.620Details
BioGPS Gene Atlas221009_s_atCingulateCortex12.0508.620Details
BioGPS Gene Atlas221009_s_atColorectaladenocarcinoma5.8008.620Details
BioGPS Gene Atlas221009_s_atDorsalRootGanglion13.0008.620Details
BioGPS Gene Atlas221009_s_atFetalThyroid8.2008.620Details
BioGPS Gene Atlas221009_s_atFetalbrain5.8508.620Details
BioGPS Gene Atlas221009_s_atFetalliver5.0508.620Details
BioGPS Gene Atlas221009_s_atFetallung4.4508.620Details
BioGPS Gene Atlas221009_s_atGlobusPallidus7.0008.620Details
BioGPS Gene Atlas221009_s_atHeart8.4008.620Details
BioGPS Gene Atlas221009_s_atHypothalamus7.9008.620Details
BioGPS Gene Atlas221009_s_atKidney5.1508.620Details
BioGPS Gene Atlas221009_s_atLeukemia_chronicMyelogenousK-5625.3008.620Details
BioGPS Gene Atlas221009_s_atLeukemia_promyelocytic-HL-605.1508.620Details
BioGPS Gene Atlas221009_s_atLeukemialymphoblastic(MOLT-4)4.7008.620Details
BioGPS Gene Atlas221009_s_atLiver61.0508.620Details
BioGPS Gene Atlas221009_s_atLung6.5508.620Details
BioGPS Gene Atlas221009_s_atLymphnode4.8508.620Details
BioGPS Gene Atlas221009_s_atLymphoma_burkitts(Daudi)7.7008.620Details
BioGPS Gene Atlas221009_s_atLymphoma_burkitts(Raji)8.2008.620Details
BioGPS Gene Atlas221009_s_atMedullaOblongata5.5508.620Details
BioGPS Gene Atlas221009_s_atOccipitalLobe5.4008.620Details
BioGPS Gene Atlas221009_s_atOlfactoryBulb5.4508.620Details
BioGPS Gene Atlas221009_s_atOvary4.5008.620Details
BioGPS Gene Atlas221009_s_atPancreas10.1508.620Details
BioGPS Gene Atlas221009_s_atPancreaticIslet32.0008.620Details
BioGPS Gene Atlas221009_s_atParietalLobe7.4008.620Details
BioGPS Gene Atlas221009_s_atPituitary7.6508.620Details
BioGPS Gene Atlas221009_s_atPlacenta17.3508.620Details
BioGPS Gene Atlas221009_s_atPons12.0008.620Details
BioGPS Gene Atlas221009_s_atPrefrontalCortex7.2008.620Details
BioGPS Gene Atlas221009_s_atProstate8.4508.620Details
BioGPS Gene Atlas221009_s_atSalivarygland4.9008.620Details
BioGPS Gene Atlas221009_s_atSkeletalMuscle9.1508.620Details
BioGPS Gene Atlas221009_s_atSkin5.0508.620Details
BioGPS Gene Atlas221009_s_atSmoothMuscle6.7508.620Details
BioGPS Gene Atlas221009_s_atSpinalcord14.0508.620Details
BioGPS Gene Atlas221009_s_atSubthalamicNucleus15.1508.620Details
BioGPS Gene Atlas221009_s_atSuperiorCervicalGanglion7.6508.620Details
BioGPS Gene Atlas221009_s_atTemporalLobe22.9008.620Details
BioGPS Gene Atlas221009_s_atTestis5.1508.620Details
BioGPS Gene Atlas221009_s_atTestisGermCell4.7508.620Details
BioGPS Gene Atlas221009_s_atTestisIntersitial5.0508.620Details
BioGPS Gene Atlas221009_s_atTestisLeydigCell5.9508.620Details
BioGPS Gene Atlas221009_s_atTestisSeminiferousTubule5.1008.620Details
BioGPS Gene Atlas221009_s_atThalamus9.4008.620Details
BioGPS Gene Atlas221009_s_atThymus4.4008.620Details
BioGPS Gene Atlas221009_s_atThyroid7.3508.620Details
BioGPS Gene Atlas221009_s_atTongue7.3508.620Details
BioGPS Gene Atlas221009_s_atTonsil5.7508.620Details
BioGPS Gene Atlas221009_s_atTrachea4.9008.620Details
BioGPS Gene Atlas221009_s_atTrigeminalGanglion7.8008.620Details
BioGPS Gene Atlas221009_s_atUterus4.7008.620Details
BioGPS Gene Atlas221009_s_atUterusCorpus6.4508.620Details
BioGPS Gene Atlas221009_s_atWholeBlood6.2508.620Details
BioGPS Gene Atlas221009_s_atWholebrain4.6508.620Details
BioGPS Gene Atlas221009_s_atcolon5.6508.620Details
BioGPS Gene Atlas221009_s_atpineal_day7.3008.620Details
BioGPS Gene Atlas221009_s_atpineal_night7.0408.620Details
BioGPS Gene Atlas221009_s_atretina7.8508.620Details
BioGPS Gene Atlas221009_s_atsmall_intestine5.5008.620Details
BioGPS NCI60221009_s_at7866.0477.710Details
BioGPS NCI60221009_s_atA1725.2887.710Details
BioGPS NCI60221009_s_atA2045.9007.710Details
BioGPS NCI60221009_s_atA3616.0237.710Details
BioGPS NCI60221009_s_atA4985.9107.710Details
BioGPS NCI60221009_s_atA54952.5837.710Details
BioGPS NCI60221009_s_atACC36.4467.710Details
BioGPS NCI60221009_s_atACHN14.3517.710Details
BioGPS NCI60221009_s_atALVA317.0267.710Details
BioGPS NCI60221009_s_atCAKI16.3067.710Details
BioGPS NCI60221009_s_atCCRT CEM7.4107.710Details
BioGPS NCI60221009_s_atCOLO2055.9187.710Details
BioGPS NCI60221009_s_atDLD15.7757.710Details
BioGPS NCI60221009_s_atDU1456.9327.710Details
BioGPS NCI60221009_s_atEKVX5.8717.710Details
BioGPS NCI60221009_s_atGM1335.9777.710Details
BioGPS NCI60221009_s_atGM16006.1197.710Details
BioGPS NCI60221009_s_atGM23136.0087.710Details
BioGPS NCI60221009_s_atGM23455.8947.710Details
BioGPS NCI60221009_s_atGM24936.1367.710Details
BioGPS NCI60221009_s_atGM976.2837.710Details
BioGPS NCI60221009_s_atHCC29984.9667.710Details
BioGPS NCI60221009_s_atHCT1165.9337.710Details
BioGPS NCI60221009_s_atHCT155.2217.710Details
BioGPS NCI60221009_s_atHEK 293 T-rex6.0987.710Details
BioGPS NCI60221009_s_atHEK 293T5.7827.710Details
BioGPS NCI60221009_s_atHEK2935.8197.710Details
BioGPS NCI60221009_s_atHELA5.6707.710Details
BioGPS NCI60221009_s_atHEPG25.9317.710Details
BioGPS NCI60221009_s_atHL606.2867.710Details
BioGPS NCI60221009_s_atHOP6218.1877.710Details
BioGPS NCI60221009_s_atHOP9219.1757.710Details
BioGPS NCI60221009_s_atHS578T5.7927.710Details
BioGPS NCI60221009_s_atHSG43.4607.710Details
BioGPS NCI60221009_s_atHT10805.6107.710Details
BioGPS NCI60221009_s_atHT296.1827.710Details
BioGPS NCI60221009_s_atIGROV15.5907.710Details
BioGPS NCI60221009_s_atIOSE805.8497.710Details
BioGPS NCI60221009_s_atJURKAT5.9577.710Details
BioGPS NCI60221009_s_atK5626.5407.710Details
BioGPS NCI60221009_s_atKM126.1767.710Details
BioGPS NCI60221009_s_atLN185.1847.710Details
BioGPS NCI60221009_s_atLNCAP5.9407.710Details
BioGPS NCI60221009_s_atLOX IMVI5.9497.710Details
BioGPS NCI60221009_s_atM145.7107.710Details
BioGPS NCI60221009_s_atMALME 3M6.5237.710Details
BioGPS NCI60221009_s_atMCF75.6077.710Details
BioGPS NCI60221009_s_atMD MB2315.9957.710Details
BioGPS NCI60221009_s_atMDA MB4356.5607.710Details
BioGPS NCI60221009_s_atMOLT46.1627.710Details
BioGPS NCI60221009_s_atNCI 4606.1967.710Details
BioGPS NCI60221009_s_atNCI H22610.5377.710Details
BioGPS NCI60221009_s_atNCI H238.7397.710Details
BioGPS NCI60221009_s_atNCI H322M6.6857.710Details
BioGPS NCI60221009_s_atNCVADR RES5.2427.710Details
BioGPS NCI60221009_s_atOVCAR36.2637.710Details
BioGPS NCI60221009_s_atOVCAR45.9237.710Details
BioGPS NCI60221009_s_atOVCAR55.9137.710Details
BioGPS NCI60221009_s_atOVCAR85.2747.710Details
BioGPS NCI60221009_s_atPANC115.3957.710Details
BioGPS NCI60221009_s_atRL75.9767.710Details
BioGPS NCI60221009_s_atRPMI 82265.9777.710Details
BioGPS NCI60221009_s_atRS118466.3007.710Details
BioGPS NCI60221009_s_atRXF39313.3017.710Details
BioGPS NCI60221009_s_atSAOS25.9917.710Details
BioGPS NCI60221009_s_atSF2685.9597.710Details
BioGPS NCI60221009_s_atSF2955.5897.710Details
BioGPS NCI60221009_s_atSF5395.6567.710Details
BioGPS NCI60221009_s_atSHSYSY+RA7.1747.710Details
BioGPS NCI60221009_s_atSHSYSY-RA17.4477.710Details
BioGPS NCI60221009_s_atSKMEL27.1257.710Details
BioGPS NCI60221009_s_atSKMEL285.8567.710Details
BioGPS NCI60221009_s_atSKMEL55.5487.710Details
BioGPS NCI60221009_s_atSKOV36.1537.710Details
BioGPS NCI60221009_s_atSN12C5.9847.710Details
BioGPS NCI60221009_s_atSNB195.3187.710Details
BioGPS NCI60221009_s_atSNB755.8377.710Details
BioGPS NCI60221009_s_atSR6.9407.710Details
BioGPS NCI60221009_s_atSW6205.9437.710Details
BioGPS NCI60221009_s_atT246.1707.710Details
BioGPS NCI60221009_s_atT3M413.6197.710Details
BioGPS NCI60221009_s_atTK105.9387.710Details
BioGPS NCI60221009_s_atU1185.4747.710Details
BioGPS NCI60221009_s_atU1386.7177.710Details
BioGPS NCI60221009_s_atU20S5.6097.710Details
BioGPS NCI60221009_s_atU2515.8057.710Details
BioGPS NCI60221009_s_atU875.4307.710Details
BioGPS NCI60221009_s_atUACC2575.7097.710Details
BioGPS NCI60221009_s_atUACC625.8837.710Details
BioGPS NCI60221009_s_atUO315.7107.710Details
BioGPS NCI60221009_s_atZR75_125.3407.710Details
BioGPS NCI60221009_s_atastrocytes5.8337.710Details
BioGPS NCI60221009_s_athuh-76.0667.710Details