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Gene ID: 81693 | AMN Antibody Resource


AMN Antibody Resource
Gene Full Name: 
amnion associated transmembrane protein
Uniprot: 
Q9BXJ7
Protein Name: 
protein amnionless
Nucleotide: 
NM_030943
Alias: 
PRO1028;amnionless;
Ensembl: 
ENSG00000166126
Location: 
14q32.3
HPRD: 
09314
NCBI Gene: 
81693
MIM: 
605799

Summary: 
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]
Function: 
Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm .
Subcellular location: 
Membrane; Single-pass type I membrane protein Potential.
PTM: 
Glycoprotein;
Disease: 
Recessive hereditary megaloblastic anemia 1 (RH-MGA1) [MIM:261100]: Due to selective malabsorption of vitamin B12. Defects in vitamin B12 absorption lead to impaired function of thymidine synthase. As a consequence DNA synthesis is interrupted. Rapidly dividing cells involved in erythropoiesis are particularly affected. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP49982_P050 AMN antibody - N-terminal region (ARP49982_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat WB 50ug $289 Details

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Product Images
AMN antibody - N-terminal region (ARP49982_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver


AMN Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP49982 Bovine AMN antibody; Bos taurus AMN antibody F1MQD9 93.0%
ARP49982 Bovine AMN antibody; Bos taurus AMN antibody Q3T152 93.0%
ARP49982 Chimpanzee AMN antibody; Pan troglodytes AMN antibody H2Q8Y4 100.0%
ARP49982 Dog AMN antibody; Canis familiaris AMN antibody Q6UKI2 86.0%
ARP49982 Giant panda AMN antibody; Ailuropoda melanoleuca AMN antibody G1MIQ5 86.0%
ARP49982 Horse AMN antibody; Equus caballus AMN antibody F6S7X6 93.0%
ARP49982 Human AMN antibody; Homo sapiens AMN antibody B3KP64 100.0%
ARP49982 Human AMN antibody; Homo sapiens AMN antibody Q9BXJ7 100.0%
ARP49982 Mouse AMN antibody; Mus musculus AMN antibody Q99JB7 100.0%
ARP49982 Pig AMN antibody; Sus scrofa AMN antibody F1SAM7 93.0%
ARP49982 Rat AMN antibody; Rattus norvegicus AMN antibody D3ZFK9 86.0%
ARP49982 Small-eared galago AMN antibody; Otolemur garnettii AMN antibody H0XME0 92.0%
ARP49982 Sumatran orangutan AMN antibody; Pongo abelii AMN antibody H2NMB4 100.0%
ARP49982 Thirteen-lined ground squirrel AMN antibody; Spermophilus tridecemlineatus AMN antibody I3NH45 100.0%
ARP49982 Zebrafish AMN antibody; Danio rerio AMN antibody A4IG97 85.0%
ARP49982 Zebrafish AMN antibody; Danio rerio AMN antibody Q08C15 85.0%
ARP49982 Zebrafish AMN antibody; Danio rerio AMN antibody Q1RLR6 85.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas220989_s_at721_B_lymphoblasts44.90057.560Details
BioGPS Gene Atlas220989_s_atAdipocyte53.85057.560Details
BioGPS Gene Atlas220989_s_atAdrenalCortex77.05057.560Details
BioGPS Gene Atlas220989_s_atAdrenalgland47.15057.560Details
BioGPS Gene Atlas220989_s_atAmygdala42.30057.560Details
BioGPS Gene Atlas220989_s_atAppendix56.45057.560Details
BioGPS Gene Atlas220989_s_atAtrioventricularNode99.95057.560Details
BioGPS Gene Atlas220989_s_atBDCA4+_DentriticCells42.05057.560Details
BioGPS Gene Atlas220989_s_atBonemarrow63.70057.560Details
BioGPS Gene Atlas220989_s_atBronchialEpithelialCells43.45057.560Details
BioGPS Gene Atlas220989_s_atCD105+_Endothelial52.10057.560Details
BioGPS Gene Atlas220989_s_atCD14+_Monocytes37.80057.560Details
BioGPS Gene Atlas220989_s_atCD19+_BCells(neg._sel.)55.35057.560Details
BioGPS Gene Atlas220989_s_atCD33+_Myeloid65.35057.560Details
BioGPS Gene Atlas220989_s_atCD34+64.80057.560Details
BioGPS Gene Atlas220989_s_atCD4+_Tcells52.65057.560Details
BioGPS Gene Atlas220989_s_atCD56+_NKCells56.70057.560Details
BioGPS Gene Atlas220989_s_atCD71+_EarlyErythroid55.25057.560Details
BioGPS Gene Atlas220989_s_atCD8+_Tcells43.70057.560Details
BioGPS Gene Atlas220989_s_atCardiacMyocytes63.45057.560Details
BioGPS Gene Atlas220989_s_atCaudatenucleus58.70057.560Details
BioGPS Gene Atlas220989_s_atCerebellum41.30057.560Details
BioGPS Gene Atlas220989_s_atCerebellumPeduncles65.85057.560Details
BioGPS Gene Atlas220989_s_atCiliaryGanglion96.15057.560Details
BioGPS Gene Atlas220989_s_atCingulateCortex61.00057.560Details
BioGPS Gene Atlas220989_s_atColorectaladenocarcinoma47.35057.560Details
BioGPS Gene Atlas220989_s_atDorsalRootGanglion70.70057.560Details
BioGPS Gene Atlas220989_s_atFetalThyroid47.60057.560Details
BioGPS Gene Atlas220989_s_atFetalbrain49.75057.560Details
BioGPS Gene Atlas220989_s_atFetalliver53.65057.560Details
BioGPS Gene Atlas220989_s_atFetallung39.50057.560Details
BioGPS Gene Atlas220989_s_atGlobusPallidus97.90057.560Details
BioGPS Gene Atlas220989_s_atHeart82.25057.560Details
BioGPS Gene Atlas220989_s_atHypothalamus53.85057.560Details
BioGPS Gene Atlas220989_s_atKidney62.20057.560Details
BioGPS Gene Atlas220989_s_atLeukemia_chronicMyelogenousK-56248.80057.560Details
BioGPS Gene Atlas220989_s_atLeukemia_promyelocytic-HL-6044.35057.560Details
BioGPS Gene Atlas220989_s_atLeukemialymphoblastic(MOLT-4)42.40057.560Details
BioGPS Gene Atlas220989_s_atLiver69.00057.560Details
BioGPS Gene Atlas220989_s_atLung57.85057.560Details
BioGPS Gene Atlas220989_s_atLymphnode41.70057.560Details
BioGPS Gene Atlas220989_s_atLymphoma_burkitts(Daudi)67.95057.560Details
BioGPS Gene Atlas220989_s_atLymphoma_burkitts(Raji)55.15057.560Details
BioGPS Gene Atlas220989_s_atMedullaOblongata57.65057.560Details
BioGPS Gene Atlas220989_s_atOccipitalLobe59.15057.560Details
BioGPS Gene Atlas220989_s_atOlfactoryBulb42.70057.560Details
BioGPS Gene Atlas220989_s_atOvary46.20057.560Details
BioGPS Gene Atlas220989_s_atPancreas45.60057.560Details
BioGPS Gene Atlas220989_s_atPancreaticIslet61.30057.560Details
BioGPS Gene Atlas220989_s_atParietalLobe65.15057.560Details
BioGPS Gene Atlas220989_s_atPituitary64.05057.560Details
BioGPS Gene Atlas220989_s_atPlacenta51.60057.560Details
BioGPS Gene Atlas220989_s_atPons73.15057.560Details
BioGPS Gene Atlas220989_s_atPrefrontalCortex64.55057.560Details
BioGPS Gene Atlas220989_s_atProstate53.10057.560Details
BioGPS Gene Atlas220989_s_atSalivarygland45.20057.560Details
BioGPS Gene Atlas220989_s_atSkeletalMuscle96.10057.560Details
BioGPS Gene Atlas220989_s_atSkin66.50057.560Details
BioGPS Gene Atlas220989_s_atSmoothMuscle53.50057.560Details
BioGPS Gene Atlas220989_s_atSpinalcord54.85057.560Details
BioGPS Gene Atlas220989_s_atSubthalamicNucleus114.60057.560Details
BioGPS Gene Atlas220989_s_atSuperiorCervicalGanglion75.85057.560Details
BioGPS Gene Atlas220989_s_atTemporalLobe66.90057.560Details
BioGPS Gene Atlas220989_s_atTestis46.85057.560Details
BioGPS Gene Atlas220989_s_atTestisGermCell39.95057.560Details
BioGPS Gene Atlas220989_s_atTestisIntersitial39.85057.560Details
BioGPS Gene Atlas220989_s_atTestisLeydigCell63.85057.560Details
BioGPS Gene Atlas220989_s_atTestisSeminiferousTubule58.20057.560Details
BioGPS Gene Atlas220989_s_atThalamus82.50057.560Details
BioGPS Gene Atlas220989_s_atThymus28.70057.560Details
BioGPS Gene Atlas220989_s_atThyroid46.20057.560Details
BioGPS Gene Atlas220989_s_atTongue82.40057.560Details
BioGPS Gene Atlas220989_s_atTonsil59.35057.560Details
BioGPS Gene Atlas220989_s_atTrachea41.90057.560Details
BioGPS Gene Atlas220989_s_atTrigeminalGanglion80.20057.560Details
BioGPS Gene Atlas220989_s_atUterus24.55057.560Details
BioGPS Gene Atlas220989_s_atUterusCorpus35.40057.560Details
BioGPS Gene Atlas220989_s_atWholeBlood27.80057.560Details
BioGPS Gene Atlas220989_s_atWholebrain35.95057.560Details
BioGPS Gene Atlas220989_s_atcolon38.55057.560Details
BioGPS Gene Atlas220989_s_atpineal_day68.44057.560Details
BioGPS Gene Atlas220989_s_atpineal_night60.10057.560Details
BioGPS Gene Atlas220989_s_atretina69.17557.560Details
BioGPS Gene Atlas220989_s_atsmall_intestine42.35057.560Details
BioGPS NCI60220989_s_at78685.96186.900Details
BioGPS NCI60220989_s_atA17228.94886.900Details
BioGPS NCI60220989_s_atA204162.21086.900Details
BioGPS NCI60220989_s_atA36179.29486.900Details
BioGPS NCI60220989_s_atA49879.39286.900Details
BioGPS NCI60220989_s_atA54980.21386.900Details
BioGPS NCI60220989_s_atACC3104.08386.900Details
BioGPS NCI60220989_s_atACHN78.25186.900Details
BioGPS NCI60220989_s_atALVA31126.47386.900Details
BioGPS NCI60220989_s_atCAKI1103.79786.900Details
BioGPS NCI60220989_s_atCCRT CEM335.70686.900Details
BioGPS NCI60220989_s_atCOLO205110.14786.900Details
BioGPS NCI60220989_s_atDLD178.06086.900Details
BioGPS NCI60220989_s_atDU14578.62286.900Details
BioGPS NCI60220989_s_atEKVX76.04886.900Details
BioGPS NCI60220989_s_atGM13340.24186.900Details
BioGPS NCI60220989_s_atGM160039.16386.900Details
BioGPS NCI60220989_s_atGM231337.66286.900Details
BioGPS NCI60220989_s_atGM234552.45786.900Details
BioGPS NCI60220989_s_atGM249339.70486.900Details
BioGPS NCI60220989_s_atGM9767.34586.900Details
BioGPS NCI60220989_s_atHCC299857.52586.900Details
BioGPS NCI60220989_s_atHCT11675.91986.900Details
BioGPS NCI60220989_s_atHCT1554.80786.900Details
BioGPS NCI60220989_s_atHEK 293 T-rex97.41286.900Details
BioGPS NCI60220989_s_atHEK 293T35.27786.900Details
BioGPS NCI60220989_s_atHEK29342.36186.900Details
BioGPS NCI60220989_s_atHELA61.39486.900Details
BioGPS NCI60220989_s_atHEPG291.04586.900Details
BioGPS NCI60220989_s_atHL6087.05686.900Details
BioGPS NCI60220989_s_atHOP6290.02386.900Details
BioGPS NCI60220989_s_atHOP9274.34286.900Details
BioGPS NCI60220989_s_atHS578T78.04086.900Details
BioGPS NCI60220989_s_atHSG77.73686.900Details
BioGPS NCI60220989_s_atHT108078.79586.900Details
BioGPS NCI60220989_s_atHT2965.84286.900Details
BioGPS NCI60220989_s_atIGROV195.64186.900Details
BioGPS NCI60220989_s_atIOSE8079.55586.900Details
BioGPS NCI60220989_s_atJURKAT119.94686.900Details
BioGPS NCI60220989_s_atK562101.40586.900Details
BioGPS NCI60220989_s_atKM12116.21286.900Details
BioGPS NCI60220989_s_atLN1838.13386.900Details
BioGPS NCI60220989_s_atLNCAP102.06086.900Details
BioGPS NCI60220989_s_atLOX IMVI143.36486.900Details
BioGPS NCI60220989_s_atM1479.06686.900Details
BioGPS NCI60220989_s_atMALME 3M225.80986.900Details
BioGPS NCI60220989_s_atMCF762.15186.900Details
BioGPS NCI60220989_s_atMD MB23183.46186.900Details
BioGPS NCI60220989_s_atMDA MB435128.74086.900Details
BioGPS NCI60220989_s_atMOLT4109.69386.900Details
BioGPS NCI60220989_s_atNCI 46087.51286.900Details
BioGPS NCI60220989_s_atNCI H22680.25486.900Details
BioGPS NCI60220989_s_atNCI H23100.96586.900Details
BioGPS NCI60220989_s_atNCI H322M79.43786.900Details
BioGPS NCI60220989_s_atNCVADR RES77.00586.900Details
BioGPS NCI60220989_s_atOVCAR3115.46486.900Details
BioGPS NCI60220989_s_atOVCAR491.01686.900Details
BioGPS NCI60220989_s_atOVCAR582.09686.900Details
BioGPS NCI60220989_s_atOVCAR863.14486.900Details
BioGPS NCI60220989_s_atPANC1217.81386.900Details
BioGPS NCI60220989_s_atRL7102.76786.900Details
BioGPS NCI60220989_s_atRPMI 8226120.48786.900Details
BioGPS NCI60220989_s_atRS11846102.52886.900Details
BioGPS NCI60220989_s_atRXF39376.43786.900Details
BioGPS NCI60220989_s_atSAOS2187.37586.900Details
BioGPS NCI60220989_s_atSF26879.19286.900Details
BioGPS NCI60220989_s_atSF29577.79886.900Details
BioGPS NCI60220989_s_atSF53984.10286.900Details
BioGPS NCI60220989_s_atSHSYSY+RA78.48886.900Details
BioGPS NCI60220989_s_atSHSYSY-RA77.13286.900Details
BioGPS NCI60220989_s_atSKMEL261.46086.900Details
BioGPS NCI60220989_s_atSKMEL28101.10586.900Details
BioGPS NCI60220989_s_atSKMEL571.70186.900Details
BioGPS NCI60220989_s_atSKOV388.81686.900Details
BioGPS NCI60220989_s_atSN12C51.95786.900Details
BioGPS NCI60220989_s_atSNB1970.29786.900Details
BioGPS NCI60220989_s_atSNB75119.69486.900Details
BioGPS NCI60220989_s_atSR87.85686.900Details
BioGPS NCI60220989_s_atSW620212.12986.900Details
BioGPS NCI60220989_s_atT2483.81086.900Details
BioGPS NCI60220989_s_atT3M4288.67086.900Details
BioGPS NCI60220989_s_atTK10129.69386.900Details
BioGPS NCI60220989_s_atU11861.36886.900Details
BioGPS NCI60220989_s_atU13843.05486.900Details
BioGPS NCI60220989_s_atU20S30.04986.900Details
BioGPS NCI60220989_s_atU25178.90586.900Details
BioGPS NCI60220989_s_atU8744.26186.900Details
BioGPS NCI60220989_s_atUACC25786.46586.900Details
BioGPS NCI60220989_s_atUACC6279.97286.900Details
BioGPS NCI60220989_s_atUO3152.02986.900Details
BioGPS NCI60220989_s_atZR75_1108.23786.900Details
BioGPS NCI60220989_s_atastrocytes40.19586.900Details
BioGPS NCI60220989_s_athuh-785.42286.900Details