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Gene ID: 246 | ALOX15 Antibody Resource


ALOX15 Antibody Resource
Gene Full Name: 
arachidonate 15-lipoxygenase
Uniprot: 
P16050
Protein Name: 
arachidonate 15-lipoxygenase
Nucleotide: 
XM_005256589
Alias: 
12-LOX;15LOX-1;15-LOX-1;
Ensembl: 
ENSG00000161905
Location: 
17p13.3
HPRD: 
01067
NCBI Gene: 
246
MIM: 
152392

Summary: 
Function: 
Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. Beside its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.
Subcellular location: 
Cytoplasm › cytosol. Cell membrane. Lipid droplet. Note: Translocates from the cytosol to the plasma membrane when stimulated by IL13/interleukin-13 and in macrophages binding apoptotic cells.
PTM: 
Disease: 
Disease susceptibility may be associated with variations affecting the gene represented in this entry. Met at position 560 may confer interindividual susceptibility to coronary artery disease (CAD) ().
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP56030_P050 ALOX15 antibody - middle region (ARP56030_P050) Polyclonal Dog, Human, Mouse, Pig, Rat WB 50ug $289 Details
Polyclonal Antibody OAEB01891 ALOX15 Antibody (OAEB01891) Human WB 0.1mg $289 Details
Polyclonal Antibody OAAB04977 ALOX15 antibody - C-terminal region (OAAB04977) Human WB, IHC, ELISA 400ul $289 Details

Show all ALOX15 antibodies


Product Images
ALOX15 antibody - middle region (ARP56030_P050) in Human Heart cells using Western Blot

Sample Type: Human Heart

ALOX15 antibody - C-terminal region (OAAB04977) in Hela, A549, K562, MDA-MB435 cells using Western Blot

Sample Type: Hela, A549, K562, MDA-MB435

ALOX15 antibody - C-terminal region (OAAB04977) in human lymph cells using Immunohistochemistry

Sample Type: human lymph

ALOX15 Antibody (OAEB01891) in Hela cells using Western Blot

Sample Type: Hela


ALOX15 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP56031 Bovine ALOX15 antibody; Bos taurus ALOX15 antibody P27479 100.0%
ARP56030 Bovine ALOX15 antibody; Bos taurus ALOX15 antibody P27479 92.0%
ARP56030 Chimpanzee ALOX15 antibody; Pan troglodytes ALOX15 antibody H2QBX9 100.0%
ARP56031 Chimpanzee ALOX15 antibody; Pan troglodytes ALOX15 antibody H2QBX9 100.0%
ARP56030 Dog ALOX15 antibody; Canis familiaris ALOX15 antibody E2R7T5 93.0%
ARP56030 Dog ALOX15 antibody; Canis familiaris ALOX15 antibody J9P4L3 93.0%
ARP56031 Dog ALOX15 antibody; Canis familiaris ALOX15 antibody E2R7T5 86.0%
ARP56031 Dog ALOX15 antibody; Canis familiaris ALOX15 antibody J9P4L3 86.0%
ARP56030 European domestic ferret ALOX15 antibody; Mustela putorius furo ALOX15 antibody M3YH81 86.0%
ARP56031 European domestic ferret ALOX15 antibody; Mustela putorius furo ALOX15 antibody M3YH81 86.0%
ARP56031 Giant panda ALOX15 antibody; Ailuropoda melanoleuca ALOX15 antibody D2HPT5 86.0%
ARP56030 Giant panda ALOX15 antibody; Ailuropoda melanoleuca ALOX15 antibody D2HPT5 79.0%
ARP56030 Human ALOX15 antibody; Homo sapiens ALOX15 antibody B7ZA11 100.0%
ARP56031 Human ALOX15 antibody; Homo sapiens ALOX15 antibody B7ZA11 100.0%
ARP56030 Human ALOX15 antibody; Homo sapiens ALOX15 antibody D3DTK1 100.0%
ARP56031 Human ALOX15 antibody; Homo sapiens ALOX15 antibody D3DTK1 100.0%
ARP56030 Human ALOX15 antibody; Homo sapiens ALOX15 antibody F5H0G8 100.0%
ARP56031 Human ALOX15 antibody; Homo sapiens ALOX15 antibody F5H0G8 100.0%
ARP56030 Human ALOX15 antibody; Homo sapiens ALOX15 antibody P16050 100.0%
ARP56031 Human ALOX15 antibody; Homo sapiens ALOX15 antibody P16050 100.0%
ARP56030 Mouse ALOX15 antibody; Mus musculus ALOX15 antibody A2CF88 85.0%
ARP56030 Mouse ALOX15 antibody; Mus musculus ALOX15 antibody P39654 85.0%
ARP56030 Pig ALOX15 antibody; Sus scrofa ALOX15 antibody P16469 100.0%
ARP56031 Pig ALOX15 antibody; Sus scrofa ALOX15 antibody P16469 93.0%
ARP56030 Rabbit ALOX15 antibody; Oryctolagus cuniculus ALOX15 antibody P12530 100.0%
ARP56031 Rabbit ALOX15 antibody; Oryctolagus cuniculus ALOX15 antibody P12530 92.0%
ARP56030 Rat ALOX15 antibody; Rattus norvegicus ALOX15 antibody Q02759 85.0%
ARP56030 Rhesus macaque ALOX15 antibody; Macaca mulatta ALOX15 antibody F7EPQ4 100.0%
ARP56031 Rhesus macaque ALOX15 antibody; Macaca mulatta ALOX15 antibody F7EPQ4 100.0%
ARP56030 Small-eared galago ALOX15 antibody; Otolemur garnettii ALOX15 antibody H0WXE1 100.0%
ARP56031 Small-eared galago ALOX15 antibody; Otolemur garnettii ALOX15 antibody H0WXE1 93.0%
ARP56030 Sumatran orangutan ALOX15 antibody; Pongo abelii ALOX15 antibody Q5RBE8 100.0%
ARP56031 Sumatran orangutan ALOX15 antibody; Pongo abelii ALOX15 antibody Q5RBE8 100.0%
ARP56030 Thirteen-lined ground squirrel ALOX15 antibody; Spermophilus tridecemlineatus ALOX15 antibody I3N674 93.0%
ARP56031 Thirteen-lined ground squirrel ALOX15 antibody; Spermophilus tridecemlineatus ALOX15 antibody I3N674 86.0%
ARP56031 White-tufted-ear marmoset ALOX15 antibody; Callithrix jacchus ALOX15 antibody U3BDB9 100.0%
ARP56030 White-tufted-ear marmoset ALOX15 antibody; Callithrix jacchus ALOX15 antibody U3BDB9 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207328_at721_B_lymphoblasts9.45011.920Details
BioGPS Gene Atlas207328_atAdipocyte10.60011.920Details
BioGPS Gene Atlas207328_atAdrenalCortex16.40011.920Details
BioGPS Gene Atlas207328_atAdrenalgland9.35011.920Details
BioGPS Gene Atlas207328_atAmygdala11.00011.920Details
BioGPS Gene Atlas207328_atAppendix17.60011.920Details
BioGPS Gene Atlas207328_atAtrioventricularNode13.35011.920Details
BioGPS Gene Atlas207328_atBDCA4+_DentriticCells11.15011.920Details
BioGPS Gene Atlas207328_atBonemarrow15.10011.920Details
BioGPS Gene Atlas207328_atBronchialEpithelialCells9.55011.920Details
BioGPS Gene Atlas207328_atCD105+_Endothelial10.55011.920Details
BioGPS Gene Atlas207328_atCD14+_Monocytes11.70011.920Details
BioGPS Gene Atlas207328_atCD19+_BCells(neg._sel.)11.20011.920Details
BioGPS Gene Atlas207328_atCD33+_Myeloid13.55011.920Details
BioGPS Gene Atlas207328_atCD34+13.20011.920Details
BioGPS Gene Atlas207328_atCD4+_Tcells11.30011.920Details
BioGPS Gene Atlas207328_atCD56+_NKCells12.30011.920Details
BioGPS Gene Atlas207328_atCD71+_EarlyErythroid11.10011.920Details
BioGPS Gene Atlas207328_atCD8+_Tcells10.05011.920Details
BioGPS Gene Atlas207328_atCardiacMyocytes15.10011.920Details
BioGPS Gene Atlas207328_atCaudatenucleus9.70011.920Details
BioGPS Gene Atlas207328_atCerebellum8.85011.920Details
BioGPS Gene Atlas207328_atCerebellumPeduncles16.05011.920Details
BioGPS Gene Atlas207328_atCiliaryGanglion11.30011.920Details
BioGPS Gene Atlas207328_atCingulateCortex11.25011.920Details
BioGPS Gene Atlas207328_atColorectaladenocarcinoma10.70011.920Details
BioGPS Gene Atlas207328_atDorsalRootGanglion11.75011.920Details
BioGPS Gene Atlas207328_atFetalThyroid10.50011.920Details
BioGPS Gene Atlas207328_atFetalbrain10.45011.920Details
BioGPS Gene Atlas207328_atFetalliver9.50011.920Details
BioGPS Gene Atlas207328_atFetallung8.65011.920Details
BioGPS Gene Atlas207328_atGlobusPallidus10.30011.920Details
BioGPS Gene Atlas207328_atHeart16.95011.920Details
BioGPS Gene Atlas207328_atHypothalamus10.40011.920Details
BioGPS Gene Atlas207328_atKidney9.55011.920Details
BioGPS Gene Atlas207328_atLeukemia_chronicMyelogenousK-5629.75011.920Details
BioGPS Gene Atlas207328_atLeukemia_promyelocytic-HL-609.50011.920Details
BioGPS Gene Atlas207328_atLeukemialymphoblastic(MOLT-4)8.40011.920Details
BioGPS Gene Atlas207328_atLiver14.55011.920Details
BioGPS Gene Atlas207328_atLung11.50011.920Details
BioGPS Gene Atlas207328_atLymphnode9.00011.920Details
BioGPS Gene Atlas207328_atLymphoma_burkitts(Daudi)14.10011.920Details
BioGPS Gene Atlas207328_atLymphoma_burkitts(Raji)15.00011.920Details
BioGPS Gene Atlas207328_atMedullaOblongata12.00011.920Details
BioGPS Gene Atlas207328_atOccipitalLobe9.80011.920Details
BioGPS Gene Atlas207328_atOlfactoryBulb8.45011.920Details
BioGPS Gene Atlas207328_atOvary10.65011.920Details
BioGPS Gene Atlas207328_atPancreas8.65011.920Details
BioGPS Gene Atlas207328_atPancreaticIslet11.45011.920Details
BioGPS Gene Atlas207328_atParietalLobe12.85011.920Details
BioGPS Gene Atlas207328_atPituitary12.55011.920Details
BioGPS Gene Atlas207328_atPlacenta10.80011.920Details
BioGPS Gene Atlas207328_atPons18.10011.920Details
BioGPS Gene Atlas207328_atPrefrontalCortex13.25011.920Details
BioGPS Gene Atlas207328_atProstate12.35011.920Details
BioGPS Gene Atlas207328_atSalivarygland8.70011.920Details
BioGPS Gene Atlas207328_atSkeletalMuscle14.50011.920Details
BioGPS Gene Atlas207328_atSkin11.05011.920Details
BioGPS Gene Atlas207328_atSmoothMuscle12.30011.920Details
BioGPS Gene Atlas207328_atSpinalcord11.50011.920Details
BioGPS Gene Atlas207328_atSubthalamicNucleus11.00011.920Details
BioGPS Gene Atlas207328_atSuperiorCervicalGanglion16.05011.920Details
BioGPS Gene Atlas207328_atTemporalLobe10.95011.920Details
BioGPS Gene Atlas207328_atTestis9.20011.920Details
BioGPS Gene Atlas207328_atTestisGermCell8.95011.920Details
BioGPS Gene Atlas207328_atTestisIntersitial10.60011.920Details
BioGPS Gene Atlas207328_atTestisLeydigCell13.20011.920Details
BioGPS Gene Atlas207328_atTestisSeminiferousTubule9.95011.920Details
BioGPS Gene Atlas207328_atThalamus11.35011.920Details
BioGPS Gene Atlas207328_atThymus8.30011.920Details
BioGPS Gene Atlas207328_atThyroid12.65011.920Details
BioGPS Gene Atlas207328_atTongue17.25011.920Details
BioGPS Gene Atlas207328_atTonsil10.55011.920Details
BioGPS Gene Atlas207328_atTrachea21.90011.920Details
BioGPS Gene Atlas207328_atTrigeminalGanglion25.25011.920Details
BioGPS Gene Atlas207328_atUterus8.55011.920Details
BioGPS Gene Atlas207328_atUterusCorpus9.65011.920Details
BioGPS Gene Atlas207328_atWholeBlood11.45011.920Details
BioGPS Gene Atlas207328_atWholebrain8.75011.920Details
BioGPS Gene Atlas207328_atcolon10.75011.920Details
BioGPS Gene Atlas207328_atpineal_day13.24011.920Details
BioGPS Gene Atlas207328_atpineal_night12.86011.920Details
BioGPS Gene Atlas207328_atretina13.37511.920Details
BioGPS Gene Atlas207328_atsmall_intestine10.00011.920Details
BioGPS NCI60207328_at7865.0115.900Details
BioGPS NCI60207328_atA1724.6055.900Details
BioGPS NCI60207328_atA2044.8875.900Details
BioGPS NCI60207328_atA3615.0095.900Details
BioGPS NCI60207328_atA4984.9385.900Details
BioGPS NCI60207328_atA5494.9825.900Details
BioGPS NCI60207328_atACC37.5155.900Details
BioGPS NCI60207328_atACHN4.4835.900Details
BioGPS NCI60207328_atALVA315.4205.900Details
BioGPS NCI60207328_atCAKI15.2445.900Details
BioGPS NCI60207328_atCCRT CEM12.2805.900Details
BioGPS NCI60207328_atCOLO2054.9045.900Details
BioGPS NCI60207328_atDLD14.8795.900Details
BioGPS NCI60207328_atDU1454.6685.900Details
BioGPS NCI60207328_atEKVX4.6495.900Details
BioGPS NCI60207328_atGM1335.0785.900Details
BioGPS NCI60207328_atGM16005.3065.900Details
BioGPS NCI60207328_atGM23135.0455.900Details
BioGPS NCI60207328_atGM23454.9535.900Details
BioGPS NCI60207328_atGM24935.3405.900Details
BioGPS NCI60207328_atGM975.8165.900Details
BioGPS NCI60207328_atHCC29984.6445.900Details
BioGPS NCI60207328_atHCT1164.9325.900Details
BioGPS NCI60207328_atHCT154.5855.900Details
BioGPS NCI60207328_atHEK 293 T-rex5.1605.900Details
BioGPS NCI60207328_atHEK 293T4.8855.900Details
BioGPS NCI60207328_atHEK2934.9025.900Details
BioGPS NCI60207328_atHELA4.5465.900Details
BioGPS NCI60207328_atHEPG24.9385.900Details
BioGPS NCI60207328_atHL606.6625.900Details
BioGPS NCI60207328_atHOP624.9375.900Details
BioGPS NCI60207328_atHOP924.7555.900Details
BioGPS NCI60207328_atHS578T4.8855.900Details
BioGPS NCI60207328_atHSG4.6655.900Details
BioGPS NCI60207328_atHT10804.9075.900Details
BioGPS NCI60207328_atHT295.5065.900Details
BioGPS NCI60207328_atIGROV14.8845.900Details
BioGPS NCI60207328_atIOSE804.9305.900Details
BioGPS NCI60207328_atJURKAT4.9155.900Details
BioGPS NCI60207328_atK5625.4585.900Details
BioGPS NCI60207328_atKM125.0845.900Details
BioGPS NCI60207328_atLN184.6465.900Details
BioGPS NCI60207328_atLNCAP93.9335.900Details
BioGPS NCI60207328_atLOX IMVI4.9085.900Details
BioGPS NCI60207328_atM144.8895.900Details
BioGPS NCI60207328_atMALME 3M5.3895.900Details
BioGPS NCI60207328_atMCF76.1265.900Details
BioGPS NCI60207328_atMD MB2315.0325.900Details
BioGPS NCI60207328_atMDA MB4355.1055.900Details
BioGPS NCI60207328_atMOLT45.2185.900Details
BioGPS NCI60207328_atNCI 4605.0965.900Details
BioGPS NCI60207328_atNCI H2265.1185.900Details
BioGPS NCI60207328_atNCI H234.9225.900Details
BioGPS NCI60207328_atNCI H322M4.9075.900Details
BioGPS NCI60207328_atNCVADR RES4.7855.900Details
BioGPS NCI60207328_atOVCAR35.2765.900Details
BioGPS NCI60207328_atOVCAR44.9095.900Details
BioGPS NCI60207328_atOVCAR54.8055.900Details
BioGPS NCI60207328_atOVCAR84.5325.900Details
BioGPS NCI60207328_atPANC14.9725.900Details
BioGPS NCI60207328_atRL74.9795.900Details
BioGPS NCI60207328_atRPMI 82265.0775.900Details
BioGPS NCI60207328_atRS118465.3325.900Details
BioGPS NCI60207328_atRXF3934.9075.900Details
BioGPS NCI60207328_atSAOS24.9665.900Details
BioGPS NCI60207328_atSF2684.9215.900Details
BioGPS NCI60207328_atSF2954.8565.900Details
BioGPS NCI60207328_atSF5394.7675.900Details
BioGPS NCI60207328_atSHSYSY+RA4.6875.900Details
BioGPS NCI60207328_atSHSYSY-RA4.8135.900Details
BioGPS NCI60207328_atSKMEL24.9225.900Details
BioGPS NCI60207328_atSKMEL284.9345.900Details
BioGPS NCI60207328_atSKMEL54.8295.900Details
BioGPS NCI60207328_atSKOV34.9885.900Details
BioGPS NCI60207328_atSN12C4.9175.900Details
BioGPS NCI60207328_atSNB194.5635.900Details
BioGPS NCI60207328_atSNB754.9095.900Details
BioGPS NCI60207328_atSR5.1325.900Details
BioGPS NCI60207328_atSW6205.0505.900Details
BioGPS NCI60207328_atT244.9905.900Details
BioGPS NCI60207328_atT3M45.2315.900Details
BioGPS NCI60207328_atTK104.8975.900Details
BioGPS NCI60207328_atU1184.7535.900Details
BioGPS NCI60207328_atU1384.5305.900Details
BioGPS NCI60207328_atU20S4.8805.900Details
BioGPS NCI60207328_atU2514.8045.900Details
BioGPS NCI60207328_atU874.7235.900Details
BioGPS NCI60207328_atUACC2574.7805.900Details
BioGPS NCI60207328_atUACC624.9685.900Details
BioGPS NCI60207328_atUO314.7185.900Details
BioGPS NCI60207328_atZR75_15.1645.900Details
BioGPS NCI60207328_atastrocytes5.0115.900Details
BioGPS NCI60207328_athuh-75.1065.900Details