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Gene ID: 440138 | ALG11 Antibody Resource


ALG11 Antibody Resource
Gene Full Name: 
ALG11, alpha-1,2-mannosyltransferase
Uniprot: 
Q2TAA5
Protein Name: 
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
Nucleotide: 
NR_036571
Alias: 
GT8;CDG1P;
Ensembl: 
ENSG00000253710
Location: 
13q14.2
HPRD: 
11265
NCBI Gene: 
440138
MIM: 
613666

Summary: 
This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010]
Function: 
Mannosyltransferase involved in the last steps of the synthesis of Man5GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum. Catalyzes the addition of the 4th and 5th mannose residues to the dolichol-linked oligosaccharide chain.
Subcellular location: 
Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein Probable .
PTM: 
Glycoprotein;
Disease: 
Congenital disorder of glycosylation 1P (CDG1P) [MIM:613661]: A multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP44463_P050 ALG11 antibody - C-terminal region (ARP44463_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish IHC, WB 50ug $289 Details
Polyclonal Antibody ARP44462_P050 ALG11 antibody - middle region (ARP44462_P050) Polyclonal Bovine, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP44461_P050 ALG11 Antibody (ARP44461_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB11217 ALG11 antibody - C - terminal region (OAAB11217) Human WB 400ul $289 Details
Polyclonal Antibody OAAB13627 ALG11 antibody - C - terminal region (OAAB13627) Human; Mouse WB 400ul $289 Details

Show all ALG11 antibodies


Product Images
ALG11 antibody - middle region (ARP44462_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

ALG11 antibody - C-terminal region (ARP44463_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

ALG11 antibody - C-terminal region (ARP44463_P050) in Human kidney cells using Immunohistochemistry

Sample Type: Human kidney

ALG11 antibody - C - terminal region (OAAB11217) in HepG2 cells using Western Blot

Sample Type: HepG2

ALG11 antibody - C - terminal region (OAAB13627) in Mouse Kidney cells using Western Blot

Sample Type: Mouse Kidney


ALG11 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44463 African clawed frog ALG11 antibody; Xenopus laevis ALG11 antibody Q08B22 93.0%
ARP44462 African clawed frog ALG11 antibody; Xenopus laevis ALG11 antibody Q08B22-2 79.0%
ARP44462 African clawed frog ALG11 antibody; Xenopus laevis ALG11 antibody Q08B22 79.0%
ARP44461 African elephant ALG11 antibody; Loxodonta africana ALG11 antibody G3TLU0 86.0%
ARP44462 African elephant ALG11 antibody; Loxodonta africana ALG11 antibody G3TLU0 86.0%
ARP44463 African elephant ALG11 antibody; Loxodonta africana ALG11 antibody G3TLU0 85.0%
ARP44462 Bovine ALG11 antibody; Bos taurus ALG11 antibody E1B756 93.0%
ARP44463 Bovine ALG11 antibody; Bos taurus ALG11 antibody E1B756 92.0%
ARP44461 Bovine ALG11 antibody; Bos taurus ALG11 antibody E1B756 86.0%
ARP44461 Cat ALG11 antibody; Felis catus ALG11 antibody M3X9F4 100.0%
ARP44463 Cat ALG11 antibody; Felis catus ALG11 antibody M3X9F4 93.0%
ARP44462 Cat ALG11 antibody; Felis catus ALG11 antibody M3X9F4 93.0%
ARP44461 Chicken ALG11 antibody; Gallus gallus ALG11 antibody E1BUY5 86.0%
ARP44463 Chicken ALG11 antibody; Gallus gallus ALG11 antibody E1BUY5 86.0%
ARP44461 Chimpanzee ALG11 antibody; Pan troglodytes ALG11 antibody H2Q7L6 100.0%
ARP44462 Chimpanzee ALG11 antibody; Pan troglodytes ALG11 antibody H2Q7L6 100.0%
ARP44463 Chimpanzee ALG11 antibody; Pan troglodytes ALG11 antibody H2Q7L6 93.0%
ARP44461 Chinese softshell turtle ALG11 antibody; Pelodiscus sinensis ALG11 antibody K7F7I4 93.0%
ARP44463 Chinese softshell turtle ALG11 antibody; Pelodiscus sinensis ALG11 antibody K7F7I4 86.0%
ARP44461 Collared flycatcher ALG11 antibody; Ficedula albicollis ALG11 antibody U3K1K1 100.0%
ARP44463 Collared flycatcher ALG11 antibody; Ficedula albicollis ALG11 antibody U3K1K1 93.0%
ARP44461 Common turkey ALG11 antibody; Meleagris gallopavo ALG11 antibody G1NQ78 86.0%
ARP44463 Common turkey ALG11 antibody; Meleagris gallopavo ALG11 antibody G1NQ78 86.0%
ARP44461 Dog ALG11 antibody; Canis familiaris ALG11 antibody E2RR35 93.0%
ARP44462 Dog ALG11 antibody; Canis familiaris ALG11 antibody E2RR35 93.0%
ARP44463 Dog ALG11 antibody; Canis familiaris ALG11 antibody E2RR35 86.0%
ARP44461 Domestic duck ALG11 antibody; Anas platyrhynchos ALG11 antibody U3IF58 86.0%
ARP44463 Domestic duck ALG11 antibody; Anas platyrhynchos ALG11 antibody U3IF58 86.0%
ARP44463 Duckbill platypus ALG11 antibody; Ornithorhynchus anatinus ALG11 antibody F6W757 86.0%
ARP44462 Duckbill platypus ALG11 antibody; Ornithorhynchus anatinus ALG11 antibody F6W757 79.0%
ARP44462 European domestic ferret ALG11 antibody; Mustela putorius furo ALG11 antibody M3Z2S6 100.0%
ARP44461 European domestic ferret ALG11 antibody; Mustela putorius furo ALG11 antibody M3Z2S6 86.0%
ARP44463 European domestic ferret ALG11 antibody; Mustela putorius furo ALG11 antibody M3Z2S6 86.0%
ARP44463 Fission yeast ALG11 antibody; Schizosaccharomyces pombe ALG11 antibody O74878 92.0%
ARP44462 Giant panda ALG11 antibody; Ailuropoda melanoleuca ALG11 antibody G1LZH2 100.0%
ARP44461 Giant panda ALG11 antibody; Ailuropoda melanoleuca ALG11 antibody G1LZH2 93.0%
ARP44463 Giant panda ALG11 antibody; Ailuropoda melanoleuca ALG11 antibody G1LZH2 79.0%
ARP44461 Gray short-tailed opossum ALG11 antibody; Monodelphis domestica ALG11 antibody F7ESN0 100.0%
ARP44463 Gray short-tailed opossum ALG11 antibody; Monodelphis domestica ALG11 antibody F7ESN0 93.0%
ARP44461 Green anole ALG11 antibody; Anolis carolinensis ALG11 antibody G1KT53 92.0%
ARP44463 Green anole ALG11 antibody; Anolis carolinensis ALG11 antibody G1KT53 86.0%
ARP44461 Horse ALG11 antibody; Equus caballus ALG11 antibody F7DAI8 100.0%
ARP44462 Horse ALG11 antibody; Equus caballus ALG11 antibody F7DAI8 100.0%
ARP44463 Horse ALG11 antibody; Equus caballus ALG11 antibody F7DAI8 100.0%
ARP44461 Human ALG11 antibody; Homo sapiens ALG11 antibody Q2TAA5 100.0%
ARP44462 Human ALG11 antibody; Homo sapiens ALG11 antibody Q2TAA5 100.0%
ARP44463 Human ALG11 antibody; Homo sapiens ALG11 antibody Q2TAA5 93.0%
ARP44461 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-2 100.0%
ARP44462 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-2 100.0%
ARP44463 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-2 100.0%
ARP44461 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-3 100.0%
ARP44462 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-3 100.0%
ARP44463 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9-3 100.0%
ARP44461 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9 100.0%
ARP44462 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9 100.0%
ARP44463 Mouse ALG11 antibody; Mus musculus ALG11 antibody Q3TZM9 100.0%
ARP44462 Pig ALG11 antibody; Sus scrofa ALG11 antibody F1RMC7 100.0%
ARP44463 Pig ALG11 antibody; Sus scrofa ALG11 antibody F1RMC7 93.0%
ARP44461 Pig ALG11 antibody; Sus scrofa ALG11 antibody F1RMC7 86.0%
ARP44461 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody U3KM07 100.0%
ARP44461 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody G1U1G7 100.0%
ARP44462 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody U3KM07 86.0%
ARP44463 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody U3KM07 86.0%
ARP44462 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody G1U1G7 86.0%
ARP44463 Rabbit ALG11 antibody; Oryctolagus cuniculus ALG11 antibody G1U1G7 86.0%
ARP44461 Rat ALG11 antibody; Rattus norvegicus ALG11 antibody D3ZCQ2 100.0%
ARP44462 Rat ALG11 antibody; Rattus norvegicus ALG11 antibody D3ZCQ2 100.0%
ARP44463 Rat ALG11 antibody; Rattus norvegicus ALG11 antibody D3ZCQ2 100.0%
ARP44461 Rhesus macaque ALG11 antibody; Macaca mulatta ALG11 antibody H9FUM4 100.0%
ARP44462 Rhesus macaque ALG11 antibody; Macaca mulatta ALG11 antibody H9FUM4 100.0%
ARP44463 Rhesus macaque ALG11 antibody; Macaca mulatta ALG11 antibody H9FUM4 93.0%
ARP44461 Small-eared galago ALG11 antibody; Otolemur garnettii ALG11 antibody H0XIT4 100.0%
ARP44462 Small-eared galago ALG11 antibody; Otolemur garnettii ALG11 antibody H0XIT4 93.0%
ARP44463 Small-eared galago ALG11 antibody; Otolemur garnettii ALG11 antibody H0XIT4 93.0%
ARP44463 Spotted green pufferfish ALG11 antibody; Tetraodon nigroviridis ALG11 antibody H3DAK7 85.0%
ARP44461 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody H2NJY5 100.0%
ARP44462 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody H2NJY5 100.0%
ARP44461 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody Q5R7Z6 100.0%
ARP44462 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody Q5R7Z6 100.0%
ARP44463 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody H2NJY5 93.0%
ARP44463 Sumatran orangutan ALG11 antibody; Pongo abelii ALG11 antibody Q5R7Z6 93.0%
ARP44461 Thirteen-lined ground squirrel ALG11 antibody; Spermophilus tridecemlineatus ALG11 antibody I3N6G0 100.0%
ARP44462 Thirteen-lined ground squirrel ALG11 antibody; Spermophilus tridecemlineatus ALG11 antibody I3N6G0 93.0%
ARP44463 Thirteen-lined ground squirrel ALG11 antibody; Spermophilus tridecemlineatus ALG11 antibody I3N6G0 93.0%
ARP44463 Western clawed frog ALG11 antibody; Xenopus tropicalis ALG11 antibody Q6P312 86.0%
ARP44462 Western clawed frog ALG11 antibody; Xenopus tropicalis ALG11 antibody Q6P312 85.0%
ARP44461 White-tufted-ear marmoset ALG11 antibody; Callithrix jacchus ALG11 antibody F7FTC2 100.0%
ARP44462 White-tufted-ear marmoset ALG11 antibody; Callithrix jacchus ALG11 antibody F7FTC2 100.0%
ARP44463 White-tufted-ear marmoset ALG11 antibody; Callithrix jacchus ALG11 antibody F7FTC2 92.0%
ARP44463 Zebra finch ALG11 antibody; Taeniopygia guttata ALG11 antibody H0ZP97 93.0%
ARP44461 Zebra finch ALG11 antibody; Taeniopygia guttata ALG11 antibody H0ZP97 90.0%
ARP44463 Zebrafish ALG11 antibody; Danio rerio ALG11 antibody F1R333 91.0%
ARP44463 Zebrafish ALG11 antibody; Danio rerio ALG11 antibody Q7ZW24 91.0%

Tissue & Cell Line Gene Expression Data