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Gene ID: 57085 | AGTRAP Antibody Resource


AGTRAP Antibody Resource
Gene Full Name: 
angiotensin II receptor-associated protein
Uniprot: 
Q6RW13
Protein Name: 
type-1 angiotensin II receptor-associated protein
Nucleotide: 
NM_001040197
Alias: 
ATRAP;
Ensembl: 
ENSG00000177674
Location: 
1p36.22
HPRD: 
16379
NCBI Gene: 
57085
MIM: 
608729

Summary: 
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Function: 
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Subcellular location: 
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note: Present in perinuclear vesicular membranes, Endoplasmic reticulum, Golgi and endocytic vesicles.
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP44927_P050 AGTRAP Antibody (ARP44927_P050) Polyclonal Bovine, Horse, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB13971 AGTRAP antibody - C - terminal region (OAAB13971) Human WB 400ul $289 Details

Show all AGTRAP antibodies


Product Images
AGTRAP antibody - C - terminal region (OAAB13971) in SK-BR-3 cells using Western Blot

Sample Type: SK-BR-3


AGTRAP Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP44927 Bovine AGTRAP antibody; Bos taurus AGTRAP antibody Q17QI4 86.0%
ARP44927 Chimpanzee AGTRAP antibody; Pan troglodytes AGTRAP antibody H2RDK2 100.0%
ARP44927 Chimpanzee AGTRAP antibody; Pan troglodytes AGTRAP antibody K6ZCM1 100.0%
ARP44927 Chimpanzee AGTRAP antibody; Pan troglodytes AGTRAP antibody K7CZ46 100.0%
ARP44927 Chimpanzee AGTRAP antibody; Pan troglodytes AGTRAP antibody K7DPW9 100.0%
ARP44927 Horse AGTRAP antibody; Equus caballus AGTRAP antibody F6YSY7 86.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody D6RB40 100.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody D6RBK6 100.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody Q6RW13-2 100.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody Q6RW13-3 100.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody Q6RW13-5 100.0%
ARP44927 Human AGTRAP antibody; Homo sapiens AGTRAP antibody Q6RW13 100.0%
ARP44927 Mouse AGTRAP antibody; Mus musculus AGTRAP antibody Q9WVK0 93.0%
ARP44927 Pig AGTRAP antibody; Sus scrofa AGTRAP antibody I3LRT0 86.0%
ARP44927 Rat AGTRAP antibody; Rattus norvegicus AGTRAP antibody Q642A2 93.0%
ARP44927 Rhesus macaque AGTRAP antibody; Macaca mulatta AGTRAP antibody F6RUB9 100.0%
ARP44927 Rhesus macaque AGTRAP antibody; Macaca mulatta AGTRAP antibody I2CU51 100.0%
ARP44927 Sumatran orangutan AGTRAP antibody; Pongo abelii AGTRAP antibody H2N938 100.0%
ARP44927 Sumatran orangutan AGTRAP antibody; Pongo abelii AGTRAP antibody Q5RER2 100.0%
ARP44927 White-tufted-ear marmoset AGTRAP antibody; Callithrix jacchus AGTRAP antibody F7DP64 100.0%
ARP44927 White-tufted-ear marmoset AGTRAP antibody; Callithrix jacchus AGTRAP antibody U3FGS3 100.0%

Tissue & Cell Line Gene Expression Data