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Gene ID: 181 | AGRP Antibody Resource


AGRP Antibody Resource
Gene Full Name: 
agouti related protein homolog (mouse)
Uniprot: 
O00253
Protein Name: 
agouti-related protein
Nucleotide: 
NM_001138
Alias: 
ART;AGRT;ASIP2;
Ensembl: 
ENSG00000159723
Location: 
16q22
HPRD: 
09079
NCBI Gene: 
181
MIM: 
602311

Summary: 
This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]
Function: 
Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R . Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Subcellular location: 
Secreted. Golgi apparatus lumen .
PTM: 
Disulfide bond;
Disease: 
Obesity (OBESITY) [MIM:601665]: A condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Protein OPPA01048 AGRP Human - Recombinant Human Agouti–Related Protein (2ug) ELISA, WB 2ug $100 Details
Polyclonal Antibody OAEB00485 Goat Anti-AGRP / Agouti-related protein Antibody (OAEB00485) Bovine, Dog, Human, Mouse, Pig ELISA 0.1mg $229 Details
Application Kit OKAG00192 AgRP ELISA Kit (Human) : 96 Wells Human 96 wells $420 Details

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Product Images
AGRP Protocols
Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59980 Chimpanzee AGRP antibody; Pan troglodytes AGRP antibody H2QBB7 100.0%
ARP59981 Chimpanzee AGRP antibody; Pan troglodytes AGRP antibody H2QBB7 100.0%
ARP59980 Gray short-tailed opossum AGRP antibody; Monodelphis domestica AGRP antibody F6XD58 85.0%
ARP59981 Horse AGRP antibody; Equus caballus AGRP antibody F6XMN7 92.0%
ARP59980 Human AGRP antibody; Homo sapiens AGRP antibody C6SUN5 100.0%
ARP59981 Human AGRP antibody; Homo sapiens AGRP antibody C6SUN5 100.0%
ARP59980 Human AGRP antibody; Homo sapiens AGRP antibody O00253 100.0%
ARP59981 Human AGRP antibody; Homo sapiens AGRP antibody O00253 100.0%
ARP59981 Pig AGRP antibody; Sus scrofa AGRP antibody D2KC52 79.0%
ARP59981 Pig AGRP antibody; Sus scrofa AGRP antibody Q8WNS0 79.0%
ARP59981 Pig AGRP antibody; Sus scrofa AGRP antibody Q9TU18 79.0%
ARP59980 Rabbit AGRP antibody; Oryctolagus cuniculus AGRP antibody G1T240 86.0%
ARP59980 Rhesus macaque AGRP antibody; Macaca mulatta AGRP antibody F7H591 93.0%
ARP59981 Rhesus macaque AGRP antibody; Macaca mulatta AGRP antibody F7H591 93.0%
ARP59980 Small-eared galago AGRP antibody; Otolemur garnettii AGRP antibody H0XI71 86.0%
ARP59981 Small-eared galago AGRP antibody; Otolemur garnettii AGRP antibody H0XI71 85.0%
ARP59981 Sumatran orangutan AGRP antibody; Pongo abelii AGRP antibody H2NR81 100.0%
ARP59980 Sumatran orangutan AGRP antibody; Pongo abelii AGRP antibody H2NR81 93.0%
ARP59981 Thirteen-lined ground squirrel AGRP antibody; Spermophilus tridecemlineatus AGRP antibody I3MRK0 85.0%
ARP59981 White-tufted-ear marmoset AGRP antibody; Callithrix jacchus AGRP antibody F7I534 93.0%
ARP59980 White-tufted-ear marmoset AGRP antibody; Callithrix jacchus AGRP antibody F7I534 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas207193_at721_B_lymphoblasts4.8503.890Details
BioGPS Gene Atlas207193_atAdipocyte3.8003.890Details
BioGPS Gene Atlas207193_atAdrenalCortex3.9503.890Details
BioGPS Gene Atlas207193_atAdrenalgland3.2503.890Details
BioGPS Gene Atlas207193_atAmygdala4.1003.890Details
BioGPS Gene Atlas207193_atAppendix3.8503.890Details
BioGPS Gene Atlas207193_atAtrioventricularNode2.9503.890Details
BioGPS Gene Atlas207193_atBDCA4+_DentriticCells4.3503.890Details
BioGPS Gene Atlas207193_atBonemarrow3.8503.890Details
BioGPS Gene Atlas207193_atBronchialEpithelialCells3.8003.890Details
BioGPS Gene Atlas207193_atCD105+_Endothelial4.0003.890Details
BioGPS Gene Atlas207193_atCD14+_Monocytes4.1003.890Details
BioGPS Gene Atlas207193_atCD19+_BCells(neg._sel.)4.1503.890Details
BioGPS Gene Atlas207193_atCD33+_Myeloid5.0003.890Details
BioGPS Gene Atlas207193_atCD34+4.9503.890Details
BioGPS Gene Atlas207193_atCD4+_Tcells4.3003.890Details
BioGPS Gene Atlas207193_atCD56+_NKCells4.7503.890Details
BioGPS Gene Atlas207193_atCD71+_EarlyErythroid3.6003.890Details
BioGPS Gene Atlas207193_atCD8+_Tcells3.8003.890Details
BioGPS Gene Atlas207193_atCardiacMyocytes4.7503.890Details
BioGPS Gene Atlas207193_atCaudatenucleus3.4503.890Details
BioGPS Gene Atlas207193_atCerebellum3.1003.890Details
BioGPS Gene Atlas207193_atCerebellumPeduncles4.4503.890Details
BioGPS Gene Atlas207193_atCiliaryGanglion2.6503.890Details
BioGPS Gene Atlas207193_atCingulateCortex3.9003.890Details
BioGPS Gene Atlas207193_atColorectaladenocarcinoma3.9003.890Details
BioGPS Gene Atlas207193_atDorsalRootGanglion2.9003.890Details
BioGPS Gene Atlas207193_atFetalThyroid3.7503.890Details
BioGPS Gene Atlas207193_atFetalbrain3.8003.890Details
BioGPS Gene Atlas207193_atFetalliver3.3503.890Details
BioGPS Gene Atlas207193_atFetallung3.2503.890Details
BioGPS Gene Atlas207193_atGlobusPallidus2.8003.890Details
BioGPS Gene Atlas207193_atHeart4.8503.890Details
BioGPS Gene Atlas207193_atHypothalamus4.2003.890Details
BioGPS Gene Atlas207193_atKidney3.2003.890Details
BioGPS Gene Atlas207193_atLeukemia_chronicMyelogenousK-5623.4503.890Details
BioGPS Gene Atlas207193_atLeukemia_promyelocytic-HL-603.4003.890Details
BioGPS Gene Atlas207193_atLeukemialymphoblastic(MOLT-4)3.1003.890Details
BioGPS Gene Atlas207193_atLiver5.7503.890Details
BioGPS Gene Atlas207193_atLung4.3003.890Details
BioGPS Gene Atlas207193_atLymphnode3.3503.890Details
BioGPS Gene Atlas207193_atLymphoma_burkitts(Daudi)4.9003.890Details
BioGPS Gene Atlas207193_atLymphoma_burkitts(Raji)5.3003.890Details
BioGPS Gene Atlas207193_atMedullaOblongata3.5503.890Details
BioGPS Gene Atlas207193_atOccipitalLobe3.4503.890Details
BioGPS Gene Atlas207193_atOlfactoryBulb3.0503.890Details
BioGPS Gene Atlas207193_atOvary2.5503.890Details
BioGPS Gene Atlas207193_atPancreas3.0503.890Details
BioGPS Gene Atlas207193_atPancreaticIslet4.1503.890Details
BioGPS Gene Atlas207193_atParietalLobe4.0503.890Details
BioGPS Gene Atlas207193_atPituitary4.5003.890Details
BioGPS Gene Atlas207193_atPlacenta4.0503.890Details
BioGPS Gene Atlas207193_atPons3.6003.890Details
BioGPS Gene Atlas207193_atPrefrontalCortex4.9003.890Details
BioGPS Gene Atlas207193_atProstate4.6003.890Details
BioGPS Gene Atlas207193_atSalivarygland3.0003.890Details
BioGPS Gene Atlas207193_atSkeletalMuscle4.2503.890Details
BioGPS Gene Atlas207193_atSkin2.8503.890Details
BioGPS Gene Atlas207193_atSmoothMuscle4.3503.890Details
BioGPS Gene Atlas207193_atSpinalcord4.1503.890Details
BioGPS Gene Atlas207193_atSubthalamicNucleus3.4503.890Details
BioGPS Gene Atlas207193_atSuperiorCervicalGanglion4.2503.890Details
BioGPS Gene Atlas207193_atTemporalLobe3.5003.890Details
BioGPS Gene Atlas207193_atTestis3.3503.890Details
BioGPS Gene Atlas207193_atTestisGermCell3.2003.890Details
BioGPS Gene Atlas207193_atTestisIntersitial3.2503.890Details
BioGPS Gene Atlas207193_atTestisLeydigCell3.7503.890Details
BioGPS Gene Atlas207193_atTestisSeminiferousTubule3.2503.890Details
BioGPS Gene Atlas207193_atThalamus3.9003.890Details
BioGPS Gene Atlas207193_atThymus3.0503.890Details
BioGPS Gene Atlas207193_atThyroid4.9003.890Details
BioGPS Gene Atlas207193_atTongue3.7003.890Details
BioGPS Gene Atlas207193_atTonsil3.7003.890Details
BioGPS Gene Atlas207193_atTrachea3.2503.890Details
BioGPS Gene Atlas207193_atTrigeminalGanglion3.8003.890Details
BioGPS Gene Atlas207193_atUterus3.2003.890Details
BioGPS Gene Atlas207193_atUterusCorpus3.4003.890Details
BioGPS Gene Atlas207193_atWholeBlood4.2003.890Details
BioGPS Gene Atlas207193_atWholebrain3.3503.890Details
BioGPS Gene Atlas207193_atcolon3.9003.890Details
BioGPS Gene Atlas207193_atpineal_day4.8203.890Details
BioGPS Gene Atlas207193_atpineal_night4.7003.890Details
BioGPS Gene Atlas207193_atretina4.6753.890Details
BioGPS Gene Atlas207193_atsmall_intestine3.7503.890Details
BioGPS NCI60207193_at7865.1585.080Details
BioGPS NCI60207193_atA1725.0225.080Details
BioGPS NCI60207193_atA2045.0405.080Details
BioGPS NCI60207193_atA3615.1105.080Details
BioGPS NCI60207193_atA4985.0745.080Details
BioGPS NCI60207193_atA5495.1425.080Details
BioGPS NCI60207193_atACC35.1705.080Details
BioGPS NCI60207193_atACHN4.9395.080Details
BioGPS NCI60207193_atALVA315.2005.080Details
BioGPS NCI60207193_atCAKI15.1795.080Details
BioGPS NCI60207193_atCCRT CEM5.3415.080Details
BioGPS NCI60207193_atCOLO2055.0385.080Details
BioGPS NCI60207193_atDLD15.0125.080Details
BioGPS NCI60207193_atDU1454.9645.080Details
BioGPS NCI60207193_atEKVX5.0035.080Details
BioGPS NCI60207193_atGM1335.1725.080Details
BioGPS NCI60207193_atGM16005.2005.080Details
BioGPS NCI60207193_atGM23135.1225.080Details
BioGPS NCI60207193_atGM23455.1075.080Details
BioGPS NCI60207193_atGM24935.2185.080Details
BioGPS NCI60207193_atGM975.2475.080Details
BioGPS NCI60207193_atHCC29984.8445.080Details
BioGPS NCI60207193_atHCT1165.0385.080Details
BioGPS NCI60207193_atHCT154.9415.080Details
BioGPS NCI60207193_atHEK 293 T-rex5.3305.080Details
BioGPS NCI60207193_atHEK 293T5.1255.080Details
BioGPS NCI60207193_atHEK2935.1305.080Details
BioGPS NCI60207193_atHELA4.9365.080Details
BioGPS NCI60207193_atHEPG25.0455.080Details
BioGPS NCI60207193_atHL605.0835.080Details
BioGPS NCI60207193_atHOP625.0945.080Details
BioGPS NCI60207193_atHOP924.8525.080Details
BioGPS NCI60207193_atHS578T5.0565.080Details
BioGPS NCI60207193_atHSG4.9725.080Details
BioGPS NCI60207193_atHT10805.0435.080Details
BioGPS NCI60207193_atHT295.1935.080Details
BioGPS NCI60207193_atIGROV15.0305.080Details
BioGPS NCI60207193_atIOSE805.0215.080Details
BioGPS NCI60207193_atJURKAT5.0745.080Details
BioGPS NCI60207193_atK5625.2345.080Details
BioGPS NCI60207193_atKM125.1825.080Details
BioGPS NCI60207193_atLN184.9915.080Details
BioGPS NCI60207193_atLNCAP5.0655.080Details
BioGPS NCI60207193_atLOX IMVI5.0635.080Details
BioGPS NCI60207193_atM145.0565.080Details
BioGPS NCI60207193_atMALME 3M5.2375.080Details
BioGPS NCI60207193_atMCF74.9965.080Details
BioGPS NCI60207193_atMD MB2315.0895.080Details
BioGPS NCI60207193_atMDA MB4355.2185.080Details
BioGPS NCI60207193_atMOLT45.1155.080Details
BioGPS NCI60207193_atNCI 4605.1345.080Details
BioGPS NCI60207193_atNCI H2265.1375.080Details
BioGPS NCI60207193_atNCI H235.0855.080Details
BioGPS NCI60207193_atNCI H322M5.0775.080Details
BioGPS NCI60207193_atNCVADR RES4.9855.080Details
BioGPS NCI60207193_atOVCAR35.1575.080Details
BioGPS NCI60207193_atOVCAR45.0365.080Details
BioGPS NCI60207193_atOVCAR55.0355.080Details
BioGPS NCI60207193_atOVCAR84.9485.080Details
BioGPS NCI60207193_atPANC15.0585.080Details
BioGPS NCI60207193_atRL75.1195.080Details
BioGPS NCI60207193_atRPMI 82265.1015.080Details
BioGPS NCI60207193_atRS118465.1925.080Details
BioGPS NCI60207193_atRXF3935.0665.080Details
BioGPS NCI60207193_atSAOS25.1085.080Details
BioGPS NCI60207193_atSF2685.0715.080Details
BioGPS NCI60207193_atSF2954.9825.080Details
BioGPS NCI60207193_atSF5394.9375.080Details
BioGPS NCI60207193_atSHSYSY+RA5.0005.080Details
BioGPS NCI60207193_atSHSYSY-RA5.0445.080Details
BioGPS NCI60207193_atSKMEL25.0705.080Details
BioGPS NCI60207193_atSKMEL285.0535.080Details
BioGPS NCI60207193_atSKMEL54.9925.080Details
BioGPS NCI60207193_atSKOV35.1265.080Details
BioGPS NCI60207193_atSN12C5.0755.080Details
BioGPS NCI60207193_atSNB194.9405.080Details
BioGPS NCI60207193_atSNB755.0435.080Details
BioGPS NCI60207193_atSR5.1345.080Details
BioGPS NCI60207193_atSW6205.0625.080Details
BioGPS NCI60207193_atT245.1065.080Details
BioGPS NCI60207193_atT3M45.1785.080Details
BioGPS NCI60207193_atTK105.0525.080Details
BioGPS NCI60207193_atU1185.0595.080Details
BioGPS NCI60207193_atU1384.9815.080Details
BioGPS NCI60207193_atU20S5.1105.080Details
BioGPS NCI60207193_atU2515.0485.080Details
BioGPS NCI60207193_atU875.0355.080Details
BioGPS NCI60207193_atUACC2575.0285.080Details
BioGPS NCI60207193_atUACC625.1185.080Details
BioGPS NCI60207193_atUO315.0275.080Details
BioGPS NCI60207193_atZR75_15.1425.080Details
BioGPS NCI60207193_atastrocytes5.1905.080Details
BioGPS NCI60207193_athuh-75.1985.080Details