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Gene ID: 178 | AGL Antibody Resource


AGL Antibody Resource
Gene Full Name: 
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
Uniprot: 
P35573
Protein Name: 
glycogen debranching enzyme
Nucleotide: 
XM_005270557
Alias: 
GDE;
Ensembl: 
ENSG00000162688
Location: 
1p21
HPRD: 
01984
NCBI Gene: 
178
MIM: 
610860

Summary: 
This gene encodes the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in this gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Function: 
Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.
Subcellular location: 
Cytoplasm. Note: Under glycogenolytic conditions localizes to the nucleus.
PTM: 
Ubl conjugation;
Disease: 
Glycogen storage disease 3 (GSD3) [MIM:232400]: A metabolic disorder associated with an accumulation of abnormal glycogen with short outer chains. It is clinically characterized by hepatomegaly, hypoglycemia, short stature, and variable myopathy. Glycogen storage disease type 3 includes different forms: GSD type 3A patients lack glycogen debrancher enzyme activity in both liver and muscle, while GSD type 3B patients are enzyme-deficient in liver only. In rare cases, selective loss of only 1 of the 2 debranching activities, glucosidase or transferase, results in GSD type 3C or type 3D, respectively. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP59979_P050 AGL Antibody (ARP59979_P050) Polyclonal Guinea pig, Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAAB15868 AGL antibody - center region (OAAB15868) Human WB, IF 400ul $289 Details
Polyclonal Antibody OAAB15869 AGL antibody - C - terminal region (OAAB15869) Human WB, IF 400ul $289 Details

Show all AGL antibodies


Product Images
AGL antibody - C - terminal region (OAAB15869) in HA-tagged, HepG2, MYC, wild-type cells using Immunofluorescence

Sample Type: HA-tagged, HepG2, MYC, wild-type

AGL antibody - C - terminal region (OAAB15869) in HepG2, Nuclear cells using Immunofluorescence

Sample Type: HepG2, Nuclear

AGL antibody - C - terminal region (OAAB15869) in Total cells using Western Blot

Sample Type: Total


AGL Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP59979 Chimpanzee AGL antibody; Pan troglodytes AGL antibody H2PZG8 100.0%
ARP59979 Human AGL antibody; Homo sapiens AGL antibody G1UI17 100.0%
ARP59979 Human AGL antibody; Homo sapiens AGL antibody P35573-2 100.0%
ARP59979 Human AGL antibody; Homo sapiens AGL antibody P35573-3 100.0%
ARP59979 Human AGL antibody; Homo sapiens AGL antibody P35573 100.0%
ARP59979 Mouse AGL antibody; Mus musculus AGL antibody F8VPN4 79.0%
ARP59979 Northern white-cheeked gibbon AGL antibody; Nomascus leucogenys AGL antibody G1RLT1 100.0%
ARP59979 Rat AGL antibody; Rattus norvegicus AGL antibody D4AEH9 79.0%
ARP59979 Rhesus macaque AGL antibody; Macaca mulatta AGL antibody F7EAR4 100.0%
ARP59979 Rhesus macaque AGL antibody; Macaca mulatta AGL antibody F7EAR8 100.0%
ARP59979 Rhesus macaque AGL antibody; Macaca mulatta AGL antibody H9EVF1 100.0%
ARP59979 Small-eared galago AGL antibody; Otolemur garnettii AGL antibody H0WSE9 93.0%
ARP59979 Small-eared galago AGL antibody; Otolemur garnettii AGL antibody H0XMV7 93.0%
ARP59979 Sumatran orangutan AGL antibody; Pongo abelii AGL antibody H2N6N7 100.0%
ARP59979 White-tufted-ear marmoset AGL antibody; Callithrix jacchus AGL antibody H9KVJ6 93.0%
ARP59979 White-tufted-ear marmoset AGL antibody; Callithrix jacchus AGL antibody U3DB08 93.0%
ARP59979 White-tufted-ear marmoset AGL antibody; Callithrix jacchus AGL antibody U3FGG2 93.0%
ARP59979 White-tufted-ear marmoset AGL antibody; Callithrix jacchus AGL antibody U3FJ79 93.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas203566_s_at721_B_lymphoblasts88.250113.670Details
BioGPS Gene Atlas203566_s_atAdipocyte33.150113.670Details
BioGPS Gene Atlas203566_s_atAdrenalCortex26.550113.670Details
BioGPS Gene Atlas203566_s_atAdrenalgland11.900113.670Details
BioGPS Gene Atlas203566_s_atAmygdala76.650113.670Details
BioGPS Gene Atlas203566_s_atAppendix34.950113.670Details
BioGPS Gene Atlas203566_s_atAtrioventricularNode15.100113.670Details
BioGPS Gene Atlas203566_s_atBDCA4+_DentriticCells21.550113.670Details
BioGPS Gene Atlas203566_s_atBonemarrow14.050113.670Details
BioGPS Gene Atlas203566_s_atBronchialEpithelialCells45.200113.670Details
BioGPS Gene Atlas203566_s_atCD105+_Endothelial28.250113.670Details
BioGPS Gene Atlas203566_s_atCD14+_Monocytes15.700113.670Details
BioGPS Gene Atlas203566_s_atCD19+_BCells(neg._sel.)27.750113.670Details
BioGPS Gene Atlas203566_s_atCD33+_Myeloid22.900113.670Details
BioGPS Gene Atlas203566_s_atCD34+39.400113.670Details
BioGPS Gene Atlas203566_s_atCD4+_Tcells32.250113.670Details
BioGPS Gene Atlas203566_s_atCD56+_NKCells61.700113.670Details
BioGPS Gene Atlas203566_s_atCD71+_EarlyErythroid12.250113.670Details
BioGPS Gene Atlas203566_s_atCD8+_Tcells50.650113.670Details
BioGPS Gene Atlas203566_s_atCardiacMyocytes21.400113.670Details
BioGPS Gene Atlas203566_s_atCaudatenucleus22.150113.670Details
BioGPS Gene Atlas203566_s_atCerebellum11.550113.670Details
BioGPS Gene Atlas203566_s_atCerebellumPeduncles24.700113.670Details
BioGPS Gene Atlas203566_s_atCiliaryGanglion21.150113.670Details
BioGPS Gene Atlas203566_s_atCingulateCortex24.050113.670Details
BioGPS Gene Atlas203566_s_atColorectaladenocarcinoma18.500113.670Details
BioGPS Gene Atlas203566_s_atDorsalRootGanglion13.550113.670Details
BioGPS Gene Atlas203566_s_atFetalThyroid30.150113.670Details
BioGPS Gene Atlas203566_s_atFetalbrain85.700113.670Details
BioGPS Gene Atlas203566_s_atFetalliver18.950113.670Details
BioGPS Gene Atlas203566_s_atFetallung13.850113.670Details
BioGPS Gene Atlas203566_s_atGlobusPallidus13.800113.670Details
BioGPS Gene Atlas203566_s_atHeart19.200113.670Details
BioGPS Gene Atlas203566_s_atHypothalamus46.200113.670Details
BioGPS Gene Atlas203566_s_atKidney12.050113.670Details
BioGPS Gene Atlas203566_s_atLeukemia_chronicMyelogenousK-56285.150113.670Details
BioGPS Gene Atlas203566_s_atLeukemia_promyelocytic-HL-6046.050113.670Details
BioGPS Gene Atlas203566_s_atLeukemialymphoblastic(MOLT-4)25.100113.670Details
BioGPS Gene Atlas203566_s_atLiver19.500113.670Details
BioGPS Gene Atlas203566_s_atLung11.400113.670Details
BioGPS Gene Atlas203566_s_atLymphnode31.450113.670Details
BioGPS Gene Atlas203566_s_atLymphoma_burkitts(Daudi)29.100113.670Details
BioGPS Gene Atlas203566_s_atLymphoma_burkitts(Raji)37.350113.670Details
BioGPS Gene Atlas203566_s_atMedullaOblongata19.750113.670Details
BioGPS Gene Atlas203566_s_atOccipitalLobe27.000113.670Details
BioGPS Gene Atlas203566_s_atOlfactoryBulb12.850113.670Details
BioGPS Gene Atlas203566_s_atOvary12.500113.670Details
BioGPS Gene Atlas203566_s_atPancreas13.100113.670Details
BioGPS Gene Atlas203566_s_atPancreaticIslet18.800113.670Details
BioGPS Gene Atlas203566_s_atParietalLobe22.600113.670Details
BioGPS Gene Atlas203566_s_atPituitary51.900113.670Details
BioGPS Gene Atlas203566_s_atPlacenta12.000113.670Details
BioGPS Gene Atlas203566_s_atPons19.000113.670Details
BioGPS Gene Atlas203566_s_atPrefrontalCortex108.200113.670Details
BioGPS Gene Atlas203566_s_atProstate48.950113.670Details
BioGPS Gene Atlas203566_s_atSalivarygland45.350113.670Details
BioGPS Gene Atlas203566_s_atSkeletalMuscle139.450113.670Details
BioGPS Gene Atlas203566_s_atSkin23.700113.670Details
BioGPS Gene Atlas203566_s_atSmoothMuscle20.400113.670Details
BioGPS Gene Atlas203566_s_atSpinalcord33.500113.670Details
BioGPS Gene Atlas203566_s_atSubthalamicNucleus18.800113.670Details
BioGPS Gene Atlas203566_s_atSuperiorCervicalGanglion25.000113.670Details
BioGPS Gene Atlas203566_s_atTemporalLobe17.550113.670Details
BioGPS Gene Atlas203566_s_atTestis10.850113.670Details
BioGPS Gene Atlas203566_s_atTestisGermCell21.900113.670Details
BioGPS Gene Atlas203566_s_atTestisIntersitial19.650113.670Details
BioGPS Gene Atlas203566_s_atTestisLeydigCell17.700113.670Details
BioGPS Gene Atlas203566_s_atTestisSeminiferousTubule14.700113.670Details
BioGPS Gene Atlas203566_s_atThalamus24.500113.670Details
BioGPS Gene Atlas203566_s_atThymus9.950113.670Details
BioGPS Gene Atlas203566_s_atThyroid259.900113.670Details
BioGPS Gene Atlas203566_s_atTongue260.050113.670Details
BioGPS Gene Atlas203566_s_atTonsil27.500113.670Details
BioGPS Gene Atlas203566_s_atTrachea20.000113.670Details
BioGPS Gene Atlas203566_s_atTrigeminalGanglion19.700113.670Details
BioGPS Gene Atlas203566_s_atUterus49.450113.670Details
BioGPS Gene Atlas203566_s_atUterusCorpus14.350113.670Details
BioGPS Gene Atlas203566_s_atWholeBlood25.200113.670Details
BioGPS Gene Atlas203566_s_atWholebrain15.800113.670Details
BioGPS Gene Atlas203566_s_atcolon78.600113.670Details
BioGPS Gene Atlas203566_s_atpineal_day1681.680113.670Details
BioGPS Gene Atlas203566_s_atpineal_night1123.760113.670Details
BioGPS Gene Atlas203566_s_atretina21.050113.670Details
BioGPS Gene Atlas203566_s_atsmall_intestine26.600113.670Details
BioGPS NCI60203566_s_at786324.535310.000Details
BioGPS NCI60203566_s_atA172206.923310.000Details
BioGPS NCI60203566_s_atA204103.841310.000Details
BioGPS NCI60203566_s_atA36126.056310.000Details
BioGPS NCI60203566_s_atA498108.185310.000Details
BioGPS NCI60203566_s_atA549242.220310.000Details
BioGPS NCI60203566_s_atACC3367.927310.000Details
BioGPS NCI60203566_s_atACHN88.991310.000Details
BioGPS NCI60203566_s_atALVA31160.329310.000Details
BioGPS NCI60203566_s_atCAKI1132.225310.000Details
BioGPS NCI60203566_s_atCCRT CEM27.639310.000Details
BioGPS NCI60203566_s_atCOLO205492.212310.000Details
BioGPS NCI60203566_s_atDLD1219.056310.000Details
BioGPS NCI60203566_s_atDU145145.528310.000Details
BioGPS NCI60203566_s_atEKVX303.870310.000Details
BioGPS NCI60203566_s_atGM133546.224310.000Details
BioGPS NCI60203566_s_atGM1600891.675310.000Details
BioGPS NCI60203566_s_atGM23131114.825310.000Details
BioGPS NCI60203566_s_atGM2345756.058310.000Details
BioGPS NCI60203566_s_atGM2493409.980310.000Details
BioGPS NCI60203566_s_atGM97155.730310.000Details
BioGPS NCI60203566_s_atHCC2998614.442310.000Details
BioGPS NCI60203566_s_atHCT116409.397310.000Details
BioGPS NCI60203566_s_atHCT15279.769310.000Details
BioGPS NCI60203566_s_atHEK 293 T-rex670.173310.000Details
BioGPS NCI60203566_s_atHEK 293T929.166310.000Details
BioGPS NCI60203566_s_atHEK293728.572310.000Details
BioGPS NCI60203566_s_atHELA203.955310.000Details
BioGPS NCI60203566_s_atHEPG2162.910310.000Details
BioGPS NCI60203566_s_atHL60233.669310.000Details
BioGPS NCI60203566_s_atHOP6282.633310.000Details
BioGPS NCI60203566_s_atHOP9286.474310.000Details
BioGPS NCI60203566_s_atHS578T57.242310.000Details
BioGPS NCI60203566_s_atHSG601.729310.000Details
BioGPS NCI60203566_s_atHT108056.847310.000Details
BioGPS NCI60203566_s_atHT291385.655310.000Details
BioGPS NCI60203566_s_atIGROV1247.862310.000Details
BioGPS NCI60203566_s_atIOSE8070.495310.000Details
BioGPS NCI60203566_s_atJURKAT715.854310.000Details
BioGPS NCI60203566_s_atK562284.946310.000Details
BioGPS NCI60203566_s_atKM12536.295310.000Details
BioGPS NCI60203566_s_atLN18529.502310.000Details
BioGPS NCI60203566_s_atLNCAP739.635310.000Details
BioGPS NCI60203566_s_atLOX IMVI71.052310.000Details
BioGPS NCI60203566_s_atM14392.577310.000Details
BioGPS NCI60203566_s_atMALME 3M30.558310.000Details
BioGPS NCI60203566_s_atMCF798.199310.000Details
BioGPS NCI60203566_s_atMD MB231127.276310.000Details
BioGPS NCI60203566_s_atMDA MB43517.885310.000Details
BioGPS NCI60203566_s_atMOLT4261.344310.000Details
BioGPS NCI60203566_s_atNCI 46098.220310.000Details
BioGPS NCI60203566_s_atNCI H226127.111310.000Details
BioGPS NCI60203566_s_atNCI H23363.404310.000Details
BioGPS NCI60203566_s_atNCI H322M238.928310.000Details
BioGPS NCI60203566_s_atNCVADR RES743.040310.000Details
BioGPS NCI60203566_s_atOVCAR3161.713310.000Details
BioGPS NCI60203566_s_atOVCAR4232.640310.000Details
BioGPS NCI60203566_s_atOVCAR5167.881310.000Details
BioGPS NCI60203566_s_atOVCAR8541.753310.000Details
BioGPS NCI60203566_s_atPANC125.272310.000Details
BioGPS NCI60203566_s_atRL7525.210310.000Details
BioGPS NCI60203566_s_atRPMI 822619.166310.000Details
BioGPS NCI60203566_s_atRS11846416.951310.000Details
BioGPS NCI60203566_s_atRXF39330.038310.000Details
BioGPS NCI60203566_s_atSAOS21115.074310.000Details
BioGPS NCI60203566_s_atSF268111.234310.000Details
BioGPS NCI60203566_s_atSF295130.013310.000Details
BioGPS NCI60203566_s_atSF539111.980310.000Details
BioGPS NCI60203566_s_atSHSYSY+RA230.675310.000Details
BioGPS NCI60203566_s_atSHSYSY-RA175.979310.000Details
BioGPS NCI60203566_s_atSKMEL2232.087310.000Details
BioGPS NCI60203566_s_atSKMEL2865.738310.000Details
BioGPS NCI60203566_s_atSKMEL5206.882310.000Details
BioGPS NCI60203566_s_atSKOV3601.799310.000Details
BioGPS NCI60203566_s_atSN12C22.792310.000Details
BioGPS NCI60203566_s_atSNB19186.719310.000Details
BioGPS NCI60203566_s_atSNB75149.121310.000Details
BioGPS NCI60203566_s_atSR43.841310.000Details
BioGPS NCI60203566_s_atSW620614.519310.000Details
BioGPS NCI60203566_s_atT2493.108310.000Details
BioGPS NCI60203566_s_atT3M4120.727310.000Details
BioGPS NCI60203566_s_atTK10211.363310.000Details
BioGPS NCI60203566_s_atU118276.339310.000Details
BioGPS NCI60203566_s_atU138289.599310.000Details
BioGPS NCI60203566_s_atU20S76.436310.000Details
BioGPS NCI60203566_s_atU251209.515310.000Details
BioGPS NCI60203566_s_atU87452.212310.000Details
BioGPS NCI60203566_s_atUACC257183.626310.000Details
BioGPS NCI60203566_s_atUACC6274.382310.000Details
BioGPS NCI60203566_s_atUO31126.630310.000Details
BioGPS NCI60203566_s_atZR75_179.900310.000Details
BioGPS NCI60203566_s_atastrocytes141.882310.000Details
BioGPS NCI60203566_s_athuh-7285.252310.000Details