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Gene ID: 133 | ADM Antibody Resource


ADM Antibody Resource
Gene Full Name: 
adrenomedullin
Uniprot: 
P35318
Protein Name: 
ADM
Nucleotide: 
NM_001124
Alias: 
AM;
Ensembl: 
Location: 
11p15.4
HPRD: 
00061
NCBI Gene: 
133
MIM: 
103275

Summary: 
Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element. [provided by RefSeq, Jul 2008]
Function: 
AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Subcellular location: 
Secreted.
PTM: 
Amidation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB02420 ADM Antibody (Center) Affinity Purified Rabbit Polyclonal Antibody (0.1 mg) Human WB, FC, ELISA 400ul $289 Details
Polyclonal Antibody ARP51920_P050 ADM antibody - C-terminal region (ARP51920_P050) Human WB 50ug $289 Details
Polyclonal Antibody ARP51919_P050 ADM Antibody (ARP51919_P050) Polyclonal Bovine, Human Not tested 50 ug $125 Details

Show all ADM antibodies


Product Images
ADM antibody - C-terminal region (ARP51920_P050) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

ADM Antibody (OAAB02420) in MDA-MB435 cells using Flow Cytometry

Sample Type: MDA-MB435

ADM Antibody (OAAB02420) in Mouse Lung cells using Western Blot

Sample Type: Mouse Lung


ADM Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP51919 Bovine ADM antibody; Bos taurus ADM antibody O62827 86.0%
ARP51919 Chimpanzee ADM antibody; Pan troglodytes ADM antibody H2Q363 100.0%
ARP51920 Chimpanzee ADM antibody; Pan troglodytes ADM antibody H2Q363 100.0%
ARP51919 European domestic ferret ADM antibody; Mustela putorius furo ADM antibody M3YN31 79.0%
ARP51919 Giant panda ADM antibody; Ailuropoda melanoleuca ADM antibody G1LA78 79.0%
ARP51919 Gray short-tailed opossum ADM antibody; Monodelphis domestica ADM antibody F7GFU5 79.0%
ARP51919 Human ADM antibody; Homo sapiens ADM antibody E9PL83 100.0%
ARP51920 Human ADM antibody; Homo sapiens ADM antibody E9PL83 100.0%
ARP51920 Human ADM antibody; Homo sapiens ADM antibody E9PQE6 100.0%
ARP51919 Human ADM antibody; Homo sapiens ADM antibody P35318 100.0%
ARP51920 Human ADM antibody; Homo sapiens ADM antibody P35318 100.0%
ARP51919 Human ADM antibody; Homo sapiens ADM antibody E9PQT2 80.0%
ARP51919 Rhesus macaque ADM antibody; Macaca mulatta ADM antibody F7G2P0 93.0%
ARP51920 Rhesus macaque ADM antibody; Macaca mulatta ADM antibody F7G2P0 86.0%
ARP51919 Small-eared galago ADM antibody; Otolemur garnettii ADM antibody H0XG78 86.0%
ARP51919 Sumatran orangutan ADM antibody; Pongo abelii ADM antibody H2NE43 100.0%
ARP51920 Sumatran orangutan ADM antibody; Pongo abelii ADM antibody H2NE43 100.0%
ARP51919 Tasmanian devil ADM antibody; Sarcophilus harrisii ADM antibody G3X3P8 86.0%
ARP51919 White-tufted-ear marmoset ADM antibody; Callithrix jacchus ADM antibody F7GWC9 100.0%
ARP51919 White-tufted-ear marmoset ADM antibody; Callithrix jacchus ADM antibody F7H196 100.0%
ARP51920 White-tufted-ear marmoset ADM antibody; Callithrix jacchus ADM antibody F7GWC9 92.0%
ARP51920 White-tufted-ear marmoset ADM antibody; Callithrix jacchus ADM antibody F7H196 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas202912_at721_B_lymphoblasts13.450140.270Details
BioGPS Gene Atlas202912_atAdipocyte859.000140.270Details
BioGPS Gene Atlas202912_atAdrenalCortex34.300140.270Details
BioGPS Gene Atlas202912_atAdrenalgland35.050140.270Details
BioGPS Gene Atlas202912_atAmygdala13.300140.270Details
BioGPS Gene Atlas202912_atAppendix386.250140.270Details
BioGPS Gene Atlas202912_atAtrioventricularNode24.350140.270Details
BioGPS Gene Atlas202912_atBDCA4+_DentriticCells21.650140.270Details
BioGPS Gene Atlas202912_atBonemarrow45.650140.270Details
BioGPS Gene Atlas202912_atBronchialEpithelialCells233.350140.270Details
BioGPS Gene Atlas202912_atCD105+_Endothelial12.900140.270Details
BioGPS Gene Atlas202912_atCD14+_Monocytes22.300140.270Details
BioGPS Gene Atlas202912_atCD19+_BCells(neg._sel.)13.400140.270Details
BioGPS Gene Atlas202912_atCD33+_Myeloid71.500140.270Details
BioGPS Gene Atlas202912_atCD34+15.750140.270Details
BioGPS Gene Atlas202912_atCD4+_Tcells13.100140.270Details
BioGPS Gene Atlas202912_atCD56+_NKCells15.000140.270Details
BioGPS Gene Atlas202912_atCD71+_EarlyErythroid13.600140.270Details
BioGPS Gene Atlas202912_atCD8+_Tcells11.200140.270Details
BioGPS Gene Atlas202912_atCardiacMyocytes108.700140.270Details
BioGPS Gene Atlas202912_atCaudatenucleus12.000140.270Details
BioGPS Gene Atlas202912_atCerebellum10.150140.270Details
BioGPS Gene Atlas202912_atCerebellumPeduncles14.800140.270Details
BioGPS Gene Atlas202912_atCiliaryGanglion245.950140.270Details
BioGPS Gene Atlas202912_atCingulateCortex29.100140.270Details
BioGPS Gene Atlas202912_atColorectaladenocarcinoma25.400140.270Details
BioGPS Gene Atlas202912_atDorsalRootGanglion14.650140.270Details
BioGPS Gene Atlas202912_atFetalThyroid14.150140.270Details
BioGPS Gene Atlas202912_atFetalbrain73.750140.270Details
BioGPS Gene Atlas202912_atFetalliver9.000140.270Details
BioGPS Gene Atlas202912_atFetallung220.200140.270Details
BioGPS Gene Atlas202912_atGlobusPallidus11.150140.270Details
BioGPS Gene Atlas202912_atHeart20.550140.270Details
BioGPS Gene Atlas202912_atHypothalamus47.350140.270Details
BioGPS Gene Atlas202912_atKidney73.750140.270Details
BioGPS Gene Atlas202912_atLeukemia_chronicMyelogenousK-56211.550140.270Details
BioGPS Gene Atlas202912_atLeukemia_promyelocytic-HL-6011.150140.270Details
BioGPS Gene Atlas202912_atLeukemialymphoblastic(MOLT-4)9.800140.270Details
BioGPS Gene Atlas202912_atLiver16.900140.270Details
BioGPS Gene Atlas202912_atLung938.950140.270Details
BioGPS Gene Atlas202912_atLymphnode33.600140.270Details
BioGPS Gene Atlas202912_atLymphoma_burkitts(Daudi)16.050140.270Details
BioGPS Gene Atlas202912_atLymphoma_burkitts(Raji)17.750140.270Details
BioGPS Gene Atlas202912_atMedullaOblongata11.450140.270Details
BioGPS Gene Atlas202912_atOccipitalLobe8.900140.270Details
BioGPS Gene Atlas202912_atOlfactoryBulb141.550140.270Details
BioGPS Gene Atlas202912_atOvary23.600140.270Details
BioGPS Gene Atlas202912_atPancreas279.900140.270Details
BioGPS Gene Atlas202912_atPancreaticIslet463.200140.270Details
BioGPS Gene Atlas202912_atParietalLobe13.300140.270Details
BioGPS Gene Atlas202912_atPituitary47.350140.270Details
BioGPS Gene Atlas202912_atPlacenta3424.050140.270Details
BioGPS Gene Atlas202912_atPons31.700140.270Details
BioGPS Gene Atlas202912_atPrefrontalCortex17.700140.270Details
BioGPS Gene Atlas202912_atProstate29.300140.270Details
BioGPS Gene Atlas202912_atSalivarygland23.150140.270Details
BioGPS Gene Atlas202912_atSkeletalMuscle53.900140.270Details
BioGPS Gene Atlas202912_atSkin477.550140.270Details
BioGPS Gene Atlas202912_atSmoothMuscle451.350140.270Details
BioGPS Gene Atlas202912_atSpinalcord103.250140.270Details
BioGPS Gene Atlas202912_atSubthalamicNucleus21.050140.270Details
BioGPS Gene Atlas202912_atSuperiorCervicalGanglion97.850140.270Details
BioGPS Gene Atlas202912_atTemporalLobe32.000140.270Details
BioGPS Gene Atlas202912_atTestis10.900140.270Details
BioGPS Gene Atlas202912_atTestisGermCell13.550140.270Details
BioGPS Gene Atlas202912_atTestisIntersitial10.700140.270Details
BioGPS Gene Atlas202912_atTestisLeydigCell12.500140.270Details
BioGPS Gene Atlas202912_atTestisSeminiferousTubule11.900140.270Details
BioGPS Gene Atlas202912_atThalamus37.000140.270Details
BioGPS Gene Atlas202912_atThymus22.450140.270Details
BioGPS Gene Atlas202912_atThyroid59.300140.270Details
BioGPS Gene Atlas202912_atTongue244.800140.270Details
BioGPS Gene Atlas202912_atTonsil17.100140.270Details
BioGPS Gene Atlas202912_atTrachea130.350140.270Details
BioGPS Gene Atlas202912_atTrigeminalGanglion195.550140.270Details
BioGPS Gene Atlas202912_atUterus24.350140.270Details
BioGPS Gene Atlas202912_atUterusCorpus71.850140.270Details
BioGPS Gene Atlas202912_atWholeBlood331.500140.270Details
BioGPS Gene Atlas202912_atWholebrain11.100140.270Details
BioGPS Gene Atlas202912_atcolon70.550140.270Details
BioGPS Gene Atlas202912_atpineal_day13.800140.270Details
BioGPS Gene Atlas202912_atpineal_night12.440140.270Details
BioGPS Gene Atlas202912_atretina667.425140.270Details
BioGPS Gene Atlas202912_atsmall_intestine74.300140.270Details
BioGPS NCI60202912_at7861302.490926.200Details
BioGPS NCI60202912_atA172527.960926.200Details
BioGPS NCI60202912_atA204239.388926.200Details
BioGPS NCI60202912_atA361621.030926.200Details
BioGPS NCI60202912_atA4981367.263926.200Details
BioGPS NCI60202912_atA549920.584926.200Details
BioGPS NCI60202912_atACC3398.866926.200Details
BioGPS NCI60202912_atACHN158.271926.200Details
BioGPS NCI60202912_atALVA3112.527926.200Details
BioGPS NCI60202912_atCAKI1379.637926.200Details
BioGPS NCI60202912_atCCRT CEM13.387926.200Details
BioGPS NCI60202912_atCOLO205169.058926.200Details
BioGPS NCI60202912_atDLD190.188926.200Details
BioGPS NCI60202912_atDU14510.096926.200Details
BioGPS NCI60202912_atEKVX314.886926.200Details
BioGPS NCI60202912_atGM1334167.530926.200Details
BioGPS NCI60202912_atGM16005936.306926.200Details
BioGPS NCI60202912_atGM23135073.795926.200Details
BioGPS NCI60202912_atGM23453910.474926.200Details
BioGPS NCI60202912_atGM24933260.452926.200Details
BioGPS NCI60202912_atGM973668.932926.200Details
BioGPS NCI60202912_atHCC2998323.842926.200Details
BioGPS NCI60202912_atHCT116782.562926.200Details
BioGPS NCI60202912_atHCT1526.524926.200Details
BioGPS NCI60202912_atHEK 293 T-rex257.938926.200Details
BioGPS NCI60202912_atHEK 293T70.388926.200Details
BioGPS NCI60202912_atHEK293348.391926.200Details
BioGPS NCI60202912_atHELA933.774926.200Details
BioGPS NCI60202912_atHEPG241.719926.200Details
BioGPS NCI60202912_atHL6017.331926.200Details
BioGPS NCI60202912_atHOP6210.584926.200Details
BioGPS NCI60202912_atHOP921303.585926.200Details
BioGPS NCI60202912_atHS578T1289.756926.200Details
BioGPS NCI60202912_atHSG4533.614926.200Details
BioGPS NCI60202912_atHT10806.081926.200Details
BioGPS NCI60202912_atHT2911.365926.200Details
BioGPS NCI60202912_atIGROV110.453926.200Details
BioGPS NCI60202912_atIOSE80813.776926.200Details
BioGPS NCI60202912_atJURKAT10.544926.200Details
BioGPS NCI60202912_atK56210.939926.200Details
BioGPS NCI60202912_atKM1242.374926.200Details
BioGPS NCI60202912_atLN18878.298926.200Details
BioGPS NCI60202912_atLNCAP10.535926.200Details
BioGPS NCI60202912_atLOX IMVI1159.772926.200Details
BioGPS NCI60202912_atM14307.522926.200Details
BioGPS NCI60202912_atMALME 3M11.253926.200Details
BioGPS NCI60202912_atMCF710.341926.200Details
BioGPS NCI60202912_atMD MB231202.671926.200Details
BioGPS NCI60202912_atMDA MB4351006.131926.200Details
BioGPS NCI60202912_atMOLT410.716926.200Details
BioGPS NCI60202912_atNCI 46040.593926.200Details
BioGPS NCI60202912_atNCI H2264182.374926.200Details
BioGPS NCI60202912_atNCI H23549.497926.200Details
BioGPS NCI60202912_atNCI H322M725.813926.200Details
BioGPS NCI60202912_atNCVADR RES469.497926.200Details
BioGPS NCI60202912_atOVCAR3207.166926.200Details
BioGPS NCI60202912_atOVCAR4116.467926.200Details
BioGPS NCI60202912_atOVCAR5415.987926.200Details
BioGPS NCI60202912_atOVCAR8277.308926.200Details
BioGPS NCI60202912_atPANC1961.198926.200Details
BioGPS NCI60202912_atRL78.546926.200Details
BioGPS NCI60202912_atRPMI 8226228.396926.200Details
BioGPS NCI60202912_atRS1184610.836926.200Details
BioGPS NCI60202912_atRXF3931897.562926.200Details
BioGPS NCI60202912_atSAOS2382.302926.200Details
BioGPS NCI60202912_atSF2685685.017926.200Details
BioGPS NCI60202912_atSF295445.460926.200Details
BioGPS NCI60202912_atSF5392568.654926.200Details
BioGPS NCI60202912_atSHSYSY+RA10.187926.200Details
BioGPS NCI60202912_atSHSYSY-RA47.357926.200Details
BioGPS NCI60202912_atSKMEL29.174926.200Details
BioGPS NCI60202912_atSKMEL2853.199926.200Details
BioGPS NCI60202912_atSKMEL51533.931926.200Details
BioGPS NCI60202912_atSKOV3282.612926.200Details
BioGPS NCI60202912_atSN12C4515.290926.200Details
BioGPS NCI60202912_atSNB19280.373926.200Details
BioGPS NCI60202912_atSNB751135.666926.200Details
BioGPS NCI60202912_atSR10.683926.200Details
BioGPS NCI60202912_atSW62040.124926.200Details
BioGPS NCI60202912_atT24620.964926.200Details
BioGPS NCI60202912_atT3M4305.350926.200Details
BioGPS NCI60202912_atTK1010.526926.200Details
BioGPS NCI60202912_atU1182360.055926.200Details
BioGPS NCI60202912_atU1384690.981926.200Details
BioGPS NCI60202912_atU20S10.309926.200Details
BioGPS NCI60202912_atU251300.256926.200Details
BioGPS NCI60202912_atU871036.696926.200Details
BioGPS NCI60202912_atUACC25710.439926.200Details
BioGPS NCI60202912_atUACC6227.413926.200Details
BioGPS NCI60202912_atUO31426.252926.200Details
BioGPS NCI60202912_atZR75_1138.311926.200Details
BioGPS NCI60202912_atastrocytes73.933926.200Details
BioGPS NCI60202912_athuh-777.129926.200Details