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Gene ID: 9719 | ADAMTSL2 Antibody Resource


ADAMTSL2 Antibody Resource
Gene Full Name: 
ADAMTS-like 2
Uniprot: 
Q86TH1
Protein Name: 
ADAMTS-like protein 2
Nucleotide: 
NM_001145320
Alias: 
GPHYSD1;
Ensembl: 
ENSG00000197859
Location: 
9q34.2
HPRD: 
11096
NCBI Gene: 
9719
MIM: 
612277

Summary: 
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
Function: 
Subcellular location: 
Secreted Potential.
PTM: 
Disulfide bond;
Disease: 
Geleophysic dysplasia 1 (GPHYSD1) [MIM:231050]: An autosomal recessive disorder characterized by severe short stature, short hands and feet, joint limitations, and skin thickening. Radiologic features include delayed bone age, cone-shaped epiphyses, shortened long tubular bones, and ovoid vertebral bodies. Affected individuals have characteristic facial features including a 'happy' face with full cheeks, shortened nose, hypertelorism, long and flat philtrum, and thin upper lip. Other distinctive features include progressive cardiac valvular thickening often leading to an early death, toe walking, tracheal stenosis, respiratory insufficiency, and lysosomal-like storage vacuoles in various tissues. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAEB00084 ADAMTSL2 Antibody (OAEB00084) Dog, Horse, Human, Mouse, Rat ELISA 0.1mg $229 Details
Polyclonal Antibody OAAB00414 ADAMTSL2 antibody - center region (OAAB00414) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP66125_P050 ADAMTSL2 Antibody (ARP66125_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rat Not tested 50 ug $125 Details
Polyclonal Antibody OAGA00156 ADAMTSL2 antibody (OAGA00156) Polyclonal Human IHC (Formalin-fixed paraffin-embedded sections), WB 100 ul $340 Details

Show all ADAMTSL2 antibodies


Product Images
ADAMTSL2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP66125 Bovine ADAMTSL2 antibody; Bos taurus ADAMTSL2 antibody E1BIY2 100.0%
ARP66125 Cat ADAMTSL2 antibody; Felis catus ADAMTSL2 antibody M3WNU5 93.0%
ARP66125 Chimpanzee ADAMTSL2 antibody; Pan troglodytes ADAMTSL2 antibody H2R0D8 100.0%
ARP66125 Dog ADAMTSL2 antibody; Canis familiaris ADAMTSL2 antibody E5D8I2 100.0%
ARP66125 Dog ADAMTSL2 antibody; Canis familiaris ADAMTSL2 antibody F1PBN7 100.0%
ARP66125 European domestic ferret ADAMTSL2 antibody; Mustela putorius furo ADAMTSL2 antibody M3YLB5 100.0%
ARP66125 Giant panda ADAMTSL2 antibody; Ailuropoda melanoleuca ADAMTSL2 antibody G1LYJ0 100.0%
ARP66125 Horse ADAMTSL2 antibody; Equus caballus ADAMTSL2 antibody F6TEW7 86.0%
ARP66125 Human ADAMTSL2 antibody; Homo sapiens ADAMTSL2 antibody B1B0D4 100.0%
ARP66125 Human ADAMTSL2 antibody; Homo sapiens ADAMTSL2 antibody Q86TH1 100.0%
ARP66125 Mouse ADAMTSL2 antibody; Mus musculus ADAMTSL2 antibody A1A5B7 93.0%
ARP66125 Mouse ADAMTSL2 antibody; Mus musculus ADAMTSL2 antibody Q6A040 93.0%
ARP66125 Mouse ADAMTSL2 antibody; Mus musculus ADAMTSL2 antibody Q7TSK7 93.0%
ARP66125 Mouse ADAMTSL2 antibody; Mus musculus ADAMTSL2 antibody Q9D201 93.0%
ARP66125 Rat ADAMTSL2 antibody; Rattus norvegicus ADAMTSL2 antibody D4A4X6 86.0%
ARP66125 Sumatran orangutan ADAMTSL2 antibody; Pongo abelii ADAMTSL2 antibody H2PTV3 100.0%
ARP66125 White-tufted-ear marmoset ADAMTSL2 antibody; Callithrix jacchus ADAMTSL2 antibody F7DIY7 92.0%
ARP66125 White-tufted-ear marmoset ADAMTSL2 antibody; Callithrix jacchus ADAMTSL2 antibody F7ECW7 92.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206629_at721_B_lymphoblasts8.0006.740Details
BioGPS Gene Atlas206629_atAdipocyte6.4006.740Details
BioGPS Gene Atlas206629_atAdrenalCortex8.4006.740Details
BioGPS Gene Atlas206629_atAdrenalgland8.2006.740Details
BioGPS Gene Atlas206629_atAmygdala6.7506.740Details
BioGPS Gene Atlas206629_atAppendix6.5006.740Details
BioGPS Gene Atlas206629_atAtrioventricularNode6.7506.740Details
BioGPS Gene Atlas206629_atBDCA4+_DentriticCells6.2506.740Details
BioGPS Gene Atlas206629_atBonemarrow7.0506.740Details
BioGPS Gene Atlas206629_atBronchialEpithelialCells6.3506.740Details
BioGPS Gene Atlas206629_atCD105+_Endothelial6.0506.740Details
BioGPS Gene Atlas206629_atCD14+_Monocytes6.7506.740Details
BioGPS Gene Atlas206629_atCD19+_BCells(neg._sel.)6.8006.740Details
BioGPS Gene Atlas206629_atCD33+_Myeloid7.4506.740Details
BioGPS Gene Atlas206629_atCD34+8.1006.740Details
BioGPS Gene Atlas206629_atCD4+_Tcells7.0006.740Details
BioGPS Gene Atlas206629_atCD56+_NKCells7.4006.740Details
BioGPS Gene Atlas206629_atCD71+_EarlyErythroid6.1006.740Details
BioGPS Gene Atlas206629_atCD8+_Tcells5.9006.740Details
BioGPS Gene Atlas206629_atCardiacMyocytes8.5506.740Details
BioGPS Gene Atlas206629_atCaudatenucleus5.8006.740Details
BioGPS Gene Atlas206629_atCerebellum5.2006.740Details
BioGPS Gene Atlas206629_atCerebellumPeduncles7.3506.740Details
BioGPS Gene Atlas206629_atCiliaryGanglion7.8506.740Details
BioGPS Gene Atlas206629_atCingulateCortex6.7006.740Details
BioGPS Gene Atlas206629_atColorectaladenocarcinoma5.9506.740Details
BioGPS Gene Atlas206629_atDorsalRootGanglion5.7506.740Details
BioGPS Gene Atlas206629_atFetalThyroid6.4006.740Details
BioGPS Gene Atlas206629_atFetalbrain7.0506.740Details
BioGPS Gene Atlas206629_atFetalliver5.6506.740Details
BioGPS Gene Atlas206629_atFetallung5.3006.740Details
BioGPS Gene Atlas206629_atGlobusPallidus5.0506.740Details
BioGPS Gene Atlas206629_atHeart8.2006.740Details
BioGPS Gene Atlas206629_atHypothalamus7.0006.740Details
BioGPS Gene Atlas206629_atKidney6.6006.740Details
BioGPS Gene Atlas206629_atLeukemia_chronicMyelogenousK-5625.8506.740Details
BioGPS Gene Atlas206629_atLeukemia_promyelocytic-HL-605.7506.740Details
BioGPS Gene Atlas206629_atLeukemialymphoblastic(MOLT-4)5.2006.740Details
BioGPS Gene Atlas206629_atLiver8.6006.740Details
BioGPS Gene Atlas206629_atLung7.2006.740Details
BioGPS Gene Atlas206629_atLymphnode5.5506.740Details
BioGPS Gene Atlas206629_atLymphoma_burkitts(Daudi)8.4006.740Details
BioGPS Gene Atlas206629_atLymphoma_burkitts(Raji)9.0006.740Details
BioGPS Gene Atlas206629_atMedullaOblongata5.7006.740Details
BioGPS Gene Atlas206629_atOccipitalLobe5.8006.740Details
BioGPS Gene Atlas206629_atOlfactoryBulb5.1006.740Details
BioGPS Gene Atlas206629_atOvary4.3006.740Details
BioGPS Gene Atlas206629_atPancreas7.3506.740Details
BioGPS Gene Atlas206629_atPancreaticIslet7.0006.740Details
BioGPS Gene Atlas206629_atParietalLobe7.0006.740Details
BioGPS Gene Atlas206629_atPituitary8.8006.740Details
BioGPS Gene Atlas206629_atPlacenta6.4006.740Details
BioGPS Gene Atlas206629_atPons6.3006.740Details
BioGPS Gene Atlas206629_atPrefrontalCortex7.9506.740Details
BioGPS Gene Atlas206629_atProstate7.5006.740Details
BioGPS Gene Atlas206629_atSalivarygland5.2006.740Details
BioGPS Gene Atlas206629_atSkeletalMuscle8.0006.740Details
BioGPS Gene Atlas206629_atSkin5.2006.740Details
BioGPS Gene Atlas206629_atSmoothMuscle7.2006.740Details
BioGPS Gene Atlas206629_atSpinalcord7.1506.740Details
BioGPS Gene Atlas206629_atSubthalamicNucleus6.0006.740Details
BioGPS Gene Atlas206629_atSuperiorCervicalGanglion7.2006.740Details
BioGPS Gene Atlas206629_atTemporalLobe5.9506.740Details
BioGPS Gene Atlas206629_atTestis5.5006.740Details
BioGPS Gene Atlas206629_atTestisGermCell5.0506.740Details
BioGPS Gene Atlas206629_atTestisIntersitial5.5006.740Details
BioGPS Gene Atlas206629_atTestisLeydigCell6.4006.740Details
BioGPS Gene Atlas206629_atTestisSeminiferousTubule5.5506.740Details
BioGPS Gene Atlas206629_atThalamus6.6506.740Details
BioGPS Gene Atlas206629_atThymus4.9006.740Details
BioGPS Gene Atlas206629_atThyroid7.8506.740Details
BioGPS Gene Atlas206629_atTongue6.3506.740Details
BioGPS Gene Atlas206629_atTonsil6.3006.740Details
BioGPS Gene Atlas206629_atTrachea5.4006.740Details
BioGPS Gene Atlas206629_atTrigeminalGanglion6.5006.740Details
BioGPS Gene Atlas206629_atUterus4.9506.740Details
BioGPS Gene Atlas206629_atUterusCorpus5.7006.740Details
BioGPS Gene Atlas206629_atWholeBlood7.0506.740Details
BioGPS Gene Atlas206629_atWholebrain5.3506.740Details
BioGPS Gene Atlas206629_atcolon5.6506.740Details
BioGPS Gene Atlas206629_atpineal_day10.2806.740Details
BioGPS Gene Atlas206629_atpineal_night8.7606.740Details
BioGPS Gene Atlas206629_atretina7.6006.740Details
BioGPS Gene Atlas206629_atsmall_intestine6.0006.740Details
BioGPS NCI60206629_at7864.0794.010Details
BioGPS NCI60206629_atA1723.8164.010Details
BioGPS NCI60206629_atA2043.9684.010Details
BioGPS NCI60206629_atA3614.0294.010Details
BioGPS NCI60206629_atA4983.9944.010Details
BioGPS NCI60206629_atA5494.0504.010Details
BioGPS NCI60206629_atACC34.1704.010Details
BioGPS NCI60206629_atACHN3.7694.010Details
BioGPS NCI60206629_atALVA314.3384.010Details
BioGPS NCI60206629_atCAKI14.1024.010Details
BioGPS NCI60206629_atCCRT CEM4.4434.010Details
BioGPS NCI60206629_atCOLO2053.9954.010Details
BioGPS NCI60206629_atDLD13.9594.010Details
BioGPS NCI60206629_atDU1453.8454.010Details
BioGPS NCI60206629_atEKVX3.8624.010Details
BioGPS NCI60206629_atGM1334.0904.010Details
BioGPS NCI60206629_atGM16004.1374.010Details
BioGPS NCI60206629_atGM23134.0574.010Details
BioGPS NCI60206629_atGM23454.0094.010Details
BioGPS NCI60206629_atGM24934.2824.010Details
BioGPS NCI60206629_atGM974.4514.010Details
BioGPS NCI60206629_atHCC29983.7634.010Details
BioGPS NCI60206629_atHCT1164.0714.010Details
BioGPS NCI60206629_atHCT153.7984.010Details
BioGPS NCI60206629_atHEK 293 T-rex4.0424.010Details
BioGPS NCI60206629_atHEK 293T3.9764.010Details
BioGPS NCI60206629_atHEK2933.9914.010Details
BioGPS NCI60206629_atHELA3.8654.010Details
BioGPS NCI60206629_atHEPG23.9884.010Details
BioGPS NCI60206629_atHL604.2234.010Details
BioGPS NCI60206629_atHOP624.0094.010Details
BioGPS NCI60206629_atHOP923.8914.010Details
BioGPS NCI60206629_atHS578T3.9594.010Details
BioGPS NCI60206629_atHSG3.8674.010Details
BioGPS NCI60206629_atHT10803.9674.010Details
BioGPS NCI60206629_atHT294.2114.010Details
BioGPS NCI60206629_atIGROV13.9344.010Details
BioGPS NCI60206629_atIOSE803.9874.010Details
BioGPS NCI60206629_atJURKAT3.9934.010Details
BioGPS NCI60206629_atK5624.2024.010Details
BioGPS NCI60206629_atKM124.1224.010Details
BioGPS NCI60206629_atLN183.7884.010Details
BioGPS NCI60206629_atLNCAP4.0044.010Details
BioGPS NCI60206629_atLOX IMVI3.9694.010Details
BioGPS NCI60206629_atM143.9604.010Details
BioGPS NCI60206629_atMALME 3M4.3324.010Details
BioGPS NCI60206629_atMCF73.8654.010Details
BioGPS NCI60206629_atMD MB2314.0714.010Details
BioGPS NCI60206629_atMDA MB4354.2694.010Details
BioGPS NCI60206629_atMOLT44.1924.010Details
BioGPS NCI60206629_atNCI 4604.0694.010Details
BioGPS NCI60206629_atNCI H2264.0704.010Details
BioGPS NCI60206629_atNCI H233.9944.010Details
BioGPS NCI60206629_atNCI H322M3.9824.010Details
BioGPS NCI60206629_atNCVADR RES3.7934.010Details
BioGPS NCI60206629_atOVCAR34.1924.010Details
BioGPS NCI60206629_atOVCAR43.9834.010Details
BioGPS NCI60206629_atOVCAR53.9214.010Details
BioGPS NCI60206629_atOVCAR83.7734.010Details
BioGPS NCI60206629_atPANC14.0374.010Details
BioGPS NCI60206629_atRL74.0504.010Details
BioGPS NCI60206629_atRPMI 82264.0334.010Details
BioGPS NCI60206629_atRS118464.1424.010Details
BioGPS NCI60206629_atRXF3933.9824.010Details
BioGPS NCI60206629_atSAOS24.0414.010Details
BioGPS NCI60206629_atSF2683.9774.010Details
BioGPS NCI60206629_atSF2953.9294.010Details
BioGPS NCI60206629_atSF5393.8554.010Details
BioGPS NCI60206629_atSHSYSY+RA3.9304.010Details
BioGPS NCI60206629_atSHSYSY-RA3.9694.010Details
BioGPS NCI60206629_atSKMEL23.9804.010Details
BioGPS NCI60206629_atSKMEL284.0084.010Details
BioGPS NCI60206629_atSKMEL53.8784.010Details
BioGPS NCI60206629_atSKOV34.1024.010Details
BioGPS NCI60206629_atSN12C3.9614.010Details
BioGPS NCI60206629_atSNB193.8144.010Details
BioGPS NCI60206629_atSNB753.9794.010Details
BioGPS NCI60206629_atSR4.1164.010Details
BioGPS NCI60206629_atSW6204.0784.010Details
BioGPS NCI60206629_atT244.0664.010Details
BioGPS NCI60206629_atT3M44.1974.010Details
BioGPS NCI60206629_atTK103.9824.010Details
BioGPS NCI60206629_atU1183.9014.010Details
BioGPS NCI60206629_atU1383.7954.010Details
BioGPS NCI60206629_atU20S3.9084.010Details
BioGPS NCI60206629_atU2513.9404.010Details
BioGPS NCI60206629_atU873.8974.010Details
BioGPS NCI60206629_atUACC2573.9114.010Details
BioGPS NCI60206629_atUACC624.0504.010Details
BioGPS NCI60206629_atUO313.8684.010Details
BioGPS NCI60206629_atZR75_14.1514.010Details
BioGPS NCI60206629_atastrocytes3.9974.010Details
BioGPS NCI60206629_athuh-74.0874.010Details