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Gene ID: 130399 | ACVR1C Antibody Resource


ACVR1C Antibody Resource
Gene Full Name: 
activin A receptor, type IC
Uniprot: 
Q8NER5
Protein Name: 
activin receptor type-1C
Nucleotide: 
NM_001111033
Alias: 
ALK7;ACVRLK7;
Ensembl: 
ENSG00000123612
Location: 
2q24.1
HPRD: 
10608
NCBI Gene: 
130399
MIM: 
608981

Summary: 
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]
Function: 
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
Subcellular location: 
Membrane; Single-pass type I membrane protein .
PTM: 
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP52836_P050 ACVR1C antibody - N-terminal region (ARP52836_P050) Polyclonal Bovine, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody OAAB04149 ACVR1C Antibody (OAAB04149) Human WB, ELISA 400ul $289 Details
Polyclonal Antibody OAPB00749 ACVR1C Antibody (OAPB00749) Polyclonal Human; Mouse; Rat ELISA, WB 0.1 mg $300 Details
Polyclonal Antibody OAAB10930 Mouse Acvr1c antibody - C - terminal region (OAAB10930) Mouse WB 400ul $289 Details
Polyclonal Antibody OAAB16871 Activin A Receptor Type IC (ACVR1C) antibody (N - terminal region A48) (OAAB16871) Human WB, IHC 400ul $289 Details
Polyclonal Antibody OAAB16872 Activin A Receptor Type IC (ACVR1C) antibody - center region (OAAB16872) Human; Mouse WB 400ul $289 Details
Polyclonal Antibody OAAF02550 ACVR1C Antibody (OAAF02550) Polyclonal Human, Mouse, Rat IHC, IF, ELISA 100 ug $229 Details

Show all ACVR1C antibodies


Product Images
ACVR1C antibody - N-terminal region (ARP52836_P050) in Human Brain cells using Western Blot

Sample Type: Human Brain

Activin A Receptor Type IC (ACVR1C) antibody (N - terminal region (OAAB16871) in Hela, HepG2, and Hela cells using Western Blot

Sample Type: Hela, HepG2, and Hela

Activin A Receptor Type IC (ACVR1C) antibody (N - terminal region (OAAB16871) in Human cancer, breast carcinoma, hepatocarcinoma cells using Immunohistochemistry

Sample Type: Human cancer, breast carcinoma, hepatocarcinoma

ACVR1C Antibody (OAAF02550) in COS-7 cells using Immunofluorescence

Sample Type: COS-7

ACVR1C Antibody (OAAF02550) in Human brain cells using Immunohistochemistry

Sample Type: Human brain

ACVR1C Antibody (OAPB00749) in human placenta cells using Western Blot

Sample Type: human placenta


ACVR1C Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP52836 Bovine ACVR1C antibody; Bos taurus ACVR1C antibody F1MMW7 100.0%
ARP52836 Cat ACVR1C antibody; Felis catus ACVR1C antibody M3WES8 81.0%
ARP52836 Chimpanzee ACVR1C antibody; Pan troglodytes ACVR1C antibody H2QIU8 100.0%
ARP52836 Dog ACVR1C antibody; Canis familiaris ACVR1C antibody E2RLG0 83.0%
ARP52836 European domestic ferret ACVR1C antibody; Mustela putorius furo ACVR1C antibody M3XN06 93.0%
ARP52836 Giant panda ACVR1C antibody; Ailuropoda melanoleuca ACVR1C antibody G1M6Z7 88.0%
ARP52836 Horse ACVR1C antibody; Equus caballus ACVR1C antibody F7CLA3 100.0%
ARP52836 Human ACVR1C antibody; Homo sapiens ACVR1C antibody Q8NER5-4 100.0%
ARP52836 Human ACVR1C antibody; Homo sapiens ACVR1C antibody Q8NER5 100.0%
ARP52836 Mouse ACVR1C antibody; Mus musculus ACVR1C antibody B7ZNG1 93.0%
ARP52836 Mouse ACVR1C antibody; Mus musculus ACVR1C antibody D3Z1K2 93.0%
ARP52836 Mouse ACVR1C antibody; Mus musculus ACVR1C antibody Q8K348 93.0%
ARP52836 Northern white-cheeked gibbon ACVR1C antibody; Nomascus leucogenys ACVR1C antibody G1QJ68 100.0%
ARP52836 Pig ACVR1C antibody; Sus scrofa ACVR1C antibody F1RPT9 81.0%
ARP52836 Rabbit ACVR1C antibody; Oryctolagus cuniculus ACVR1C antibody G1SWR9 100.0%
ARP52836 Rat ACVR1C antibody; Rattus norvegicus ACVR1C antibody F1LQM3 86.0%
ARP52836 Rat ACVR1C antibody; Rattus norvegicus ACVR1C antibody P70539 79.0%
ARP52836 Rhesus macaque ACVR1C antibody; Macaca mulatta ACVR1C antibody F6S9J1 100.0%
ARP52836 Rhesus macaque ACVR1C antibody; Macaca mulatta ACVR1C antibody F7GDQ6 100.0%
ARP52836 Small-eared galago ACVR1C antibody; Otolemur garnettii ACVR1C antibody H0X5W2 100.0%
ARP52836 White-tufted-ear marmoset ACVR1C antibody; Callithrix jacchus ACVR1C antibody F6ZNW8 100.0%
ARP52836 White-tufted-ear marmoset ACVR1C antibody; Callithrix jacchus ACVR1C antibody F7H6A3 100.0%

Tissue & Cell Line Gene Expression Data