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Gene ID: 197322 | ACSF3 Antibody Resource


ACSF3 Antibody Resource
Gene Full Name: 
acyl-CoA synthetase family member 3
Uniprot: 
Q4G176
Protein Name: 
acyl-CoA synthetase family member 3, mitochondrial
Nucleotide: 
NM_001243279
Alias: 
Ensembl: 
ENSG00000176715
Location: 
16q24.3
HPRD: 
14117
NCBI Gene: 
197322
MIM: 
614245

Summary: 
This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]
Function: 
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates.
Subcellular location: 
Mitochondrion .
PTM: 
Disease: 
Combined malonic and methylmalonic aciduria (CMAMMA) [MIM:614265]: A metabolic disease characterized by malonic and methylmalonic aciduria, with urinary excretion of much larger amounts of methylmalonic acid than malonic acid, in the presence of normal malonyl-CoA decarboxylase activity. Clinical features include coma, ketoacidosis, hypoglycemia, failure to thrive, microcephaly, dystonia, axial hypotonia and/or developmental delay, and neurologic manifestations including seizures, psychiatric disease and/or cognitive decline. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB03310 ACSF3 antibody - center region (OAAB03310) Human; Mouse WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody ARP53306_P050 ACSF3 Antibody (ARP53306_P050) Polyclonal Bovine, Guinea pig, Horse, Human, Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP53307_P050 ACSF3 Antibody - C-terminal region (ARP53307_P050) Polyclonal Human WB 50ug $289 Details

Show all ACSF3 antibodies


Product Images
ACSF3 Antibody - C-terminal region (ARP53307_P050) in Human MCF7 cells using Western Blot

Sample Type: Human MCF7

ACSF3 antibody - center region (OAAB03310) in Human Tonsil cells using Immunohistochemistry

Sample Type: Human Tonsil

ACSF3 antibody - center region (OAAB03310) in Mouse Heart cells using Western Blot

Sample Type: Mouse Heart


ACSF3 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP53307 African clawed frog ACSF3 antibody; Xenopus laevis ACSF3 antibody Q6GLK6 93.0%
ARP53306 Bovine ACSF3 antibody; Bos taurus ACSF3 antibody Q58DN7 100.0%
ARP53307 Bovine ACSF3 antibody; Bos taurus ACSF3 antibody Q58DN7 93.0%
ARP53307 Cat ACSF3 antibody; Felis catus ACSF3 antibody M3W1R6 93.0%
ARP53306 Cat ACSF3 antibody; Felis catus ACSF3 antibody M3W1R6 79.0%
ARP53307 Chicken ACSF3 antibody; Gallus gallus ACSF3 antibody F1NXK4 86.0%
ARP53307 Chimpanzee ACSF3 antibody; Pan troglodytes ACSF3 antibody K7AV26 100.0%
ARP53306 Chimpanzee ACSF3 antibody; Pan troglodytes ACSF3 antibody H2QBR1 93.0%
ARP53306 Chimpanzee ACSF3 antibody; Pan troglodytes ACSF3 antibody K7AV26 93.0%
ARP53307 Chinese softshell turtle ACSF3 antibody; Pelodiscus sinensis ACSF3 antibody K7G3Y4 93.0%
ARP53307 Collared flycatcher ACSF3 antibody; Ficedula albicollis ACSF3 antibody U3JKV5 86.0%
ARP53307 Dog ACSF3 antibody; Canis familiaris ACSF3 antibody F1P6L8 93.0%
ARP53307 Dog ACSF3 antibody; Canis familiaris ACSF3 antibody G1CSK7 93.0%
ARP53307 European domestic ferret ACSF3 antibody; Mustela putorius furo ACSF3 antibody M3Y898 93.0%
ARP53306 European domestic ferret ACSF3 antibody; Mustela putorius furo ACSF3 antibody M3Y898 79.0%
ARP53307 Giant panda ACSF3 antibody; Ailuropoda melanoleuca ACSF3 antibody G1LAK3 93.0%
ARP53307 Gray short-tailed opossum ACSF3 antibody; Monodelphis domestica ACSF3 antibody F7DU27 93.0%
ARP53307 Green anole ACSF3 antibody; Anolis carolinensis ACSF3 antibody H9GJM9 93.0%
ARP53307 Green anole ACSF3 antibody; Anolis carolinensis ACSF3 antibody R4GCH9 93.0%
ARP53306 Green anole ACSF3 antibody; Anolis carolinensis ACSF3 antibody H9GJM9 83.0%
ARP53306 Green anole ACSF3 antibody; Anolis carolinensis ACSF3 antibody R4GCH9 83.0%
ARP53307 Horse ACSF3 antibody; Equus caballus ACSF3 antibody F7DM96 93.0%
ARP53306 Horse ACSF3 antibody; Equus caballus ACSF3 antibody F7DM96 79.0%
ARP53306 Human ACSF3 antibody; Homo sapiens ACSF3 antibody F5H362 100.0%
ARP53306 Human ACSF3 antibody; Homo sapiens ACSF3 antibody F5H5A1 100.0%
ARP53307 Human ACSF3 antibody; Homo sapiens ACSF3 antibody F5H5A1 100.0%
ARP53306 Human ACSF3 antibody; Homo sapiens ACSF3 antibody F5H755 100.0%
ARP53307 Human ACSF3 antibody; Homo sapiens ACSF3 antibody F5H755 100.0%
ARP53306 Human ACSF3 antibody; Homo sapiens ACSF3 antibody Q4G176 100.0%
ARP53307 Human ACSF3 antibody; Homo sapiens ACSF3 antibody Q4G176 100.0%
ARP53306 Human ACSF3 antibody; Homo sapiens ACSF3 antibody Q6P2C7 100.0%
ARP53307 Human ACSF3 antibody; Homo sapiens ACSF3 antibody Q6P2C7 100.0%
ARP53306 Mouse ACSF3 antibody; Mus musculus ACSF3 antibody Q3URE1 100.0%
ARP53307 Mouse ACSF3 antibody; Mus musculus ACSF3 antibody Q3URE1 100.0%
ARP53306 Rat ACSF3 antibody; Rattus norvegicus ACSF3 antibody D3ZUX7 100.0%
ARP53307 Rat ACSF3 antibody; Rattus norvegicus ACSF3 antibody D3ZUX7 100.0%
ARP53307 Rhesus macaque ACSF3 antibody; Macaca mulatta ACSF3 antibody H9F3H6 100.0%
ARP53307 Rhesus macaque ACSF3 antibody; Macaca mulatta ACSF3 antibody H9Z635 100.0%
ARP53306 Rhesus macaque ACSF3 antibody; Macaca mulatta ACSF3 antibody H9F3H6 93.0%
ARP53306 Rhesus macaque ACSF3 antibody; Macaca mulatta ACSF3 antibody H9Z635 93.0%
ARP53306 Small-eared galago ACSF3 antibody; Otolemur garnettii ACSF3 antibody H0WIC5 93.0%
ARP53307 Small-eared galago ACSF3 antibody; Otolemur garnettii ACSF3 antibody H0WIC5 93.0%
ARP53307 Southern platyfish ACSF3 antibody; Xiphophorus maculatus ACSF3 antibody M4AAA2 86.0%
ARP53307 Spotted green pufferfish ACSF3 antibody; Tetraodon nigroviridis ACSF3 antibody H3CVK0 86.0%
ARP53307 Sumatran orangutan ACSF3 antibody; Pongo abelii ACSF3 antibody H2NRT4 100.0%
ARP53306 Sumatran orangutan ACSF3 antibody; Pongo abelii ACSF3 antibody H2NRT4 93.0%
ARP53307 Tasmanian devil ACSF3 antibody; Sarcophilus harrisii ACSF3 antibody G3WHV6 93.0%
ARP53307 Thirteen-lined ground squirrel ACSF3 antibody; Spermophilus tridecemlineatus ACSF3 antibody I3N4B0 100.0%
ARP53306 Thirteen-lined ground squirrel ACSF3 antibody; Spermophilus tridecemlineatus ACSF3 antibody I3N4B0 91.0%
ARP53307 Three-spined stickleback ACSF3 antibody; Gasterosteus aculeatus ACSF3 antibody G3PRY2 86.0%
ARP53307 Western clawed frog ACSF3 antibody; Xenopus tropicalis ACSF3 antibody B2GU01 93.0%
ARP53307 White-tufted-ear marmoset ACSF3 antibody; Callithrix jacchus ACSF3 antibody U3F770 100.0%
ARP53307 White-tufted-ear marmoset ACSF3 antibody; Callithrix jacchus ACSF3 antibody F7FYW6 100.0%
ARP53307 White-tufted-ear marmoset ACSF3 antibody; Callithrix jacchus ACSF3 antibody F7GAR5 100.0%
ARP53306 White-tufted-ear marmoset ACSF3 antibody; Callithrix jacchus ACSF3 antibody U3F770 93.0%
ARP53306 White-tufted-ear marmoset ACSF3 antibody; Callithrix jacchus ACSF3 antibody F7FYW6 93.0%
ARP53307 Zebra finch ACSF3 antibody; Taeniopygia guttata ACSF3 antibody H0ZBU4 86.0%

Tissue & Cell Line Gene Expression Data