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Gene ID: 65057 | Acd Antibody Resource


Acd Antibody Resource
Gene Full Name: 
adrenocortical dysplasia homolog (mouse)
Uniprot: 
Q96AP0
Protein Name: 
adrenocortical dysplasia protein homolog
Nucleotide: 
NM_001082487
Alias: 
PIP1;PTOP;TPP1;TINT1;
Ensembl: 
ENSG00000102977
Location: 
16q22.1
HPRD: 
12417
NCBI Gene: 
65057
MIM: 
609377

Summary: 
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq, Jul 2008]
Function: 
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.
Subcellular location: 
Nucleus. Chromosome › telomere .
PTM: 
Phosphoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP58254_P050 ACD antibody - C-terminal region (ARP58254_P050) Polyclonal Human WB 50ug $289 Details
Polyclonal Antibody ARP58253_P050 ACD antibody - middle region (ARP58253_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP36813_P050 Acd antibody - C-terminal region (ARP36813_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Rat WB 50ug $289 Details
Polyclonal Antibody ARP36814_P050 Acd Antibody (ARP36814_P050) Polyclonal Mouse, Rat Not tested 50 ug $125 Details
Polyclonal Antibody ARP58255_P050 ACD Antibody (ARP58255_P050) Polyclonal Dog, Human, Pig Not tested 50 ug $125 Details

Show all Acd antibodies


Product Images
Acd antibody - C-terminal region (ARP36813_P050) in Mouse Muscle cells using Western Blot

Sample Type: Mouse Muscle

ACD antibody - middle region (ARP58253_P050) in Human NCI-H226 cells using Western Blot

Sample Type: Human NCI-H226

ACD antibody - C-terminal region (ARP58254_P050) in Human Brain cells using Western Blot

Sample Type: Human Brain


Acd Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP60390 Glaciecola pallidula DSM 14239 = ACAM 615 Acd antibody K6ZKJ6 85.0%
ARP60389 Glaciecola lipolytica E3 Acd antibody K6WXA2 83.0%
ARP58253 Bovine Acd antibody; Bos taurus Acd antibody A6QQ10 100.0%
ARP36813 Bovine Acd antibody; Bos taurus Acd antibody A6QQ10 83.0%
ARP58253 Cat Acd antibody; Felis catus Acd antibody M3WB51 93.0%
ARP58255 Cat Acd antibody; Felis catus Acd antibody M3WB51 86.0%
ARP36813 Cat Acd antibody; Felis catus Acd antibody M3WB51 83.0%
ARP58253 Chimpanzee Acd antibody; Pan troglodytes Acd antibody H2QBC1 100.0%
ARP58254 Chimpanzee Acd antibody; Pan troglodytes Acd antibody H2QBC1 100.0%
ARP58255 Chimpanzee Acd antibody; Pan troglodytes Acd antibody H2QBC1 100.0%
ARP36813 Chimpanzee Acd antibody; Pan troglodytes Acd antibody H2QBC1 85.0%
ARP58253 Dog Acd antibody; Canis familiaris Acd antibody E2RTA7 100.0%
ARP58253 Dog Acd antibody; Canis familiaris Acd antibody F1P9G5 100.0%
ARP58253 Dog Acd antibody; Canis familiaris Acd antibody J9P1T2 100.0%
ARP58255 Dog Acd antibody; Canis familiaris Acd antibody E2RTA7 86.0%
ARP58255 Dog Acd antibody; Canis familiaris Acd antibody F1P9G5 86.0%
ARP58255 Dog Acd antibody; Canis familiaris Acd antibody J9P1T2 86.0%
ARP36813 Dog Acd antibody; Canis familiaris Acd antibody E2RTA7 85.0%
ARP36813 Dog Acd antibody; Canis familiaris Acd antibody F1P9G5 85.0%
ARP36813 Dog Acd antibody; Canis familiaris Acd antibody J9P1T2 85.0%
ARP58253 European domestic ferret Acd antibody; Mustela putorius furo Acd antibody M3Y4V2 93.0%
ARP36813 European domestic ferret Acd antibody; Mustela putorius furo Acd antibody M3Y4V2 85.0%
ARP58253 Horse Acd antibody; Equus caballus Acd antibody F7CJX5 100.0%
ARP36813 Horse Acd antibody; Equus caballus Acd antibody F7CJX5 85.0%
ARP36814 Horse Acd antibody; Equus caballus Acd antibody F7CJX5 79.0%
ARP58255 Horse Acd antibody; Equus caballus Acd antibody F7CJX5 79.0%
ARP58253 Human Acd antibody; Homo sapiens Acd antibody Q96AP0-2 100.0%
ARP58254 Human Acd antibody; Homo sapiens Acd antibody Q96AP0-2 100.0%
ARP58255 Human Acd antibody; Homo sapiens Acd antibody Q96AP0-2 100.0%
ARP58253 Human Acd antibody; Homo sapiens Acd antibody Q96AP0 100.0%
ARP58254 Human Acd antibody; Homo sapiens Acd antibody Q96AP0 100.0%
ARP58255 Human Acd antibody; Homo sapiens Acd antibody Q96AP0 100.0%
ARP58254 Human Acd antibody; Homo sapiens Acd antibody R4GND4 100.0%
ARP58254 Human Acd antibody; Homo sapiens Acd antibody R4GNJ5 100.0%
ARP58255 Human Acd antibody; Homo sapiens Acd antibody R4GNJ5 100.0%
ARP36813 Human Acd antibody; Homo sapiens Acd antibody Q96AP0-2 85.0%
ARP36813 Human Acd antibody; Homo sapiens Acd antibody Q96AP0 85.0%
ARP36814 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38 100.0%
ARP36813 Mouse Acd antibody; Mus musculus Acd antibody B2RS36 100.0%
ARP36814 Mouse Acd antibody; Mus musculus Acd antibody B2RS36 100.0%
ARP36813 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-2 100.0%
ARP36813 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-3 100.0%
ARP36813 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-4 100.0%
ARP36813 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38 100.0%
ARP58253 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38 85.0%
ARP58253 Mouse Acd antibody; Mus musculus Acd antibody B2RS36 85.0%
ARP58253 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-2 85.0%
ARP58253 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-3 85.0%
ARP58253 Mouse Acd antibody; Mus musculus Acd antibody Q5EE38-4 85.0%
ARP58253 Pig Acd antibody; Sus scrofa Acd antibody I3LST0 86.0%
ARP58255 Pig Acd antibody; Sus scrofa Acd antibody I3LST0 79.0%
ARP36814 Rat Acd antibody; Rattus norvegicus Acd antibody Q4FZR5 100.0%
ARP36813 Rat Acd antibody; Rattus norvegicus Acd antibody Q4FZR5 93.0%
ARP58253 Rat Acd antibody; Rattus norvegicus Acd antibody Q4FZR5 83.0%
ARP58253 Rhesus macaque Acd antibody; Macaca mulatta Acd antibody F6XSB4 100.0%
ARP58254 Rhesus macaque Acd antibody; Macaca mulatta Acd antibody F6XSB4 86.0%
ARP58255 Rhesus macaque Acd antibody; Macaca mulatta Acd antibody F6XSB4 86.0%
ARP36813 Rhesus macaque Acd antibody; Macaca mulatta Acd antibody F6XSB4 85.0%
ARP58253 Small-eared galago Acd antibody; Otolemur garnettii Acd antibody H0XLU2 100.0%
ARP36813 Small-eared galago Acd antibody; Otolemur garnettii Acd antibody H0XLU2 83.0%
ARP58253 Sumatran orangutan Acd antibody; Pongo abelii Acd antibody H2NR85 100.0%
ARP58254 Sumatran orangutan Acd antibody; Pongo abelii Acd antibody H2NR85 100.0%
ARP58255 Sumatran orangutan Acd antibody; Pongo abelii Acd antibody H2NR85 100.0%
ARP36813 Sumatran orangutan Acd antibody; Pongo abelii Acd antibody H2NR85 85.0%
ARP58253 Thirteen-lined ground squirrel Acd antibody; Spermophilus tridecemlineatus Acd antibody I3MRK5 86.0%
ARP58253 White-tufted-ear marmoset Acd antibody; Callithrix jacchus Acd antibody F7IRE2 86.0%
ARP58255 White-tufted-ear marmoset Acd antibody; Callithrix jacchus Acd antibody F7IRE2 86.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas204617_s_at721_B_lymphoblasts323.70072.480Details
BioGPS Gene Atlas204617_s_atAdipocyte43.60072.480Details
BioGPS Gene Atlas204617_s_atAdrenalCortex62.40072.480Details
BioGPS Gene Atlas204617_s_atAdrenalgland45.40072.480Details
BioGPS Gene Atlas204617_s_atAmygdala57.80072.480Details
BioGPS Gene Atlas204617_s_atAppendix66.90072.480Details
BioGPS Gene Atlas204617_s_atAtrioventricularNode60.55072.480Details
BioGPS Gene Atlas204617_s_atBDCA4+_DentriticCells79.25072.480Details
BioGPS Gene Atlas204617_s_atBonemarrow55.80072.480Details
BioGPS Gene Atlas204617_s_atBronchialEpithelialCells55.55072.480Details
BioGPS Gene Atlas204617_s_atCD105+_Endothelial60.90072.480Details
BioGPS Gene Atlas204617_s_atCD14+_Monocytes69.65072.480Details
BioGPS Gene Atlas204617_s_atCD19+_BCells(neg._sel.)65.45072.480Details
BioGPS Gene Atlas204617_s_atCD33+_Myeloid55.85072.480Details
BioGPS Gene Atlas204617_s_atCD34+222.55072.480Details
BioGPS Gene Atlas204617_s_atCD4+_Tcells145.80072.480Details
BioGPS Gene Atlas204617_s_atCD56+_NKCells221.85072.480Details
BioGPS Gene Atlas204617_s_atCD71+_EarlyErythroid45.35072.480Details
BioGPS Gene Atlas204617_s_atCD8+_Tcells170.70072.480Details
BioGPS Gene Atlas204617_s_atCardiacMyocytes74.70072.480Details
BioGPS Gene Atlas204617_s_atCaudatenucleus43.80072.480Details
BioGPS Gene Atlas204617_s_atCerebellum58.10072.480Details
BioGPS Gene Atlas204617_s_atCerebellumPeduncles103.60072.480Details
BioGPS Gene Atlas204617_s_atCiliaryGanglion40.05072.480Details
BioGPS Gene Atlas204617_s_atCingulateCortex75.75072.480Details
BioGPS Gene Atlas204617_s_atColorectaladenocarcinoma80.70072.480Details
BioGPS Gene Atlas204617_s_atDorsalRootGanglion47.55072.480Details
BioGPS Gene Atlas204617_s_atFetalThyroid77.90072.480Details
BioGPS Gene Atlas204617_s_atFetalbrain67.90072.480Details
BioGPS Gene Atlas204617_s_atFetalliver40.35072.480Details
BioGPS Gene Atlas204617_s_atFetallung42.95072.480Details
BioGPS Gene Atlas204617_s_atGlobusPallidus41.15072.480Details
BioGPS Gene Atlas204617_s_atHeart81.05072.480Details
BioGPS Gene Atlas204617_s_atHypothalamus76.85072.480Details
BioGPS Gene Atlas204617_s_atKidney41.45072.480Details
BioGPS Gene Atlas204617_s_atLeukemia_chronicMyelogenousK-56259.25072.480Details
BioGPS Gene Atlas204617_s_atLeukemia_promyelocytic-HL-6051.30072.480Details
BioGPS Gene Atlas204617_s_atLeukemialymphoblastic(MOLT-4)100.75072.480Details
BioGPS Gene Atlas204617_s_atLiver64.25072.480Details
BioGPS Gene Atlas204617_s_atLung83.00072.480Details
BioGPS Gene Atlas204617_s_atLymphnode47.70072.480Details
BioGPS Gene Atlas204617_s_atLymphoma_burkitts(Daudi)59.50072.480Details
BioGPS Gene Atlas204617_s_atLymphoma_burkitts(Raji)193.65072.480Details
BioGPS Gene Atlas204617_s_atMedullaOblongata47.50072.480Details
BioGPS Gene Atlas204617_s_atOccipitalLobe47.25072.480Details
BioGPS Gene Atlas204617_s_atOlfactoryBulb47.80072.480Details
BioGPS Gene Atlas204617_s_atOvary36.50072.480Details
BioGPS Gene Atlas204617_s_atPancreas33.90072.480Details
BioGPS Gene Atlas204617_s_atPancreaticIslet57.15072.480Details
BioGPS Gene Atlas204617_s_atParietalLobe64.45072.480Details
BioGPS Gene Atlas204617_s_atPituitary57.00072.480Details
BioGPS Gene Atlas204617_s_atPlacenta30.65072.480Details
BioGPS Gene Atlas204617_s_atPons53.35072.480Details
BioGPS Gene Atlas204617_s_atPrefrontalCortex97.55072.480Details
BioGPS Gene Atlas204617_s_atProstate97.95072.480Details
BioGPS Gene Atlas204617_s_atSalivarygland39.05072.480Details
BioGPS Gene Atlas204617_s_atSkeletalMuscle83.10072.480Details
BioGPS Gene Atlas204617_s_atSkin50.75072.480Details
BioGPS Gene Atlas204617_s_atSmoothMuscle45.85072.480Details
BioGPS Gene Atlas204617_s_atSpinalcord53.80072.480Details
BioGPS Gene Atlas204617_s_atSubthalamicNucleus46.25072.480Details
BioGPS Gene Atlas204617_s_atSuperiorCervicalGanglion64.95072.480Details
BioGPS Gene Atlas204617_s_atTemporalLobe48.75072.480Details
BioGPS Gene Atlas204617_s_atTestis99.30072.480Details
BioGPS Gene Atlas204617_s_atTestisGermCell79.25072.480Details
BioGPS Gene Atlas204617_s_atTestisIntersitial65.30072.480Details
BioGPS Gene Atlas204617_s_atTestisLeydigCell69.85072.480Details
BioGPS Gene Atlas204617_s_atTestisSeminiferousTubule95.90072.480Details
BioGPS Gene Atlas204617_s_atThalamus49.65072.480Details
BioGPS Gene Atlas204617_s_atThymus76.80072.480Details
BioGPS Gene Atlas204617_s_atThyroid101.75072.480Details
BioGPS Gene Atlas204617_s_atTongue69.75072.480Details
BioGPS Gene Atlas204617_s_atTonsil64.95072.480Details
BioGPS Gene Atlas204617_s_atTrachea40.20072.480Details
BioGPS Gene Atlas204617_s_atTrigeminalGanglion54.25072.480Details
BioGPS Gene Atlas204617_s_atUterus67.10072.480Details
BioGPS Gene Atlas204617_s_atUterusCorpus51.65072.480Details
BioGPS Gene Atlas204617_s_atWholeBlood64.20072.480Details
BioGPS Gene Atlas204617_s_atWholebrain62.25072.480Details
BioGPS Gene Atlas204617_s_atcolon40.55072.480Details
BioGPS Gene Atlas204617_s_atpineal_day73.00072.480Details
BioGPS Gene Atlas204617_s_atpineal_night80.08072.480Details
BioGPS Gene Atlas204617_s_atretina67.27572.480Details
BioGPS Gene Atlas204617_s_atsmall_intestine42.65072.480Details
BioGPS NCI60204617_s_at786599.160594.300Details
BioGPS NCI60204617_s_atA172626.799594.300Details
BioGPS NCI60204617_s_atA204263.664594.300Details
BioGPS NCI60204617_s_atA361186.816594.300Details
BioGPS NCI60204617_s_atA498591.799594.300Details
BioGPS NCI60204617_s_atA549489.135594.300Details
BioGPS NCI60204617_s_atACC3536.722594.300Details
BioGPS NCI60204617_s_atACHN662.218594.300Details
BioGPS NCI60204617_s_atALVA31421.871594.300Details
BioGPS NCI60204617_s_atCAKI1514.444594.300Details
BioGPS NCI60204617_s_atCCRT CEM478.389594.300Details
BioGPS NCI60204617_s_atCOLO205326.683594.300Details
BioGPS NCI60204617_s_atDLD11050.844594.300Details
BioGPS NCI60204617_s_atDU145644.132594.300Details
BioGPS NCI60204617_s_atEKVX460.947594.300Details
BioGPS NCI60204617_s_atGM133393.828594.300Details
BioGPS NCI60204617_s_atGM1600365.562594.300Details
BioGPS NCI60204617_s_atGM2313392.859594.300Details
BioGPS NCI60204617_s_atGM2345263.285594.300Details
BioGPS NCI60204617_s_atGM2493283.906594.300Details
BioGPS NCI60204617_s_atGM97555.913594.300Details
BioGPS NCI60204617_s_atHCC2998635.595594.300Details
BioGPS NCI60204617_s_atHCT1161342.370594.300Details
BioGPS NCI60204617_s_atHCT15952.717594.300Details
BioGPS NCI60204617_s_atHEK 293 T-rex380.885594.300Details
BioGPS NCI60204617_s_atHEK 293T655.761594.300Details
BioGPS NCI60204617_s_atHEK293369.236594.300Details
BioGPS NCI60204617_s_atHELA309.173594.300Details
BioGPS NCI60204617_s_atHEPG21060.927594.300Details
BioGPS NCI60204617_s_atHL60390.187594.300Details
BioGPS NCI60204617_s_atHOP62525.901594.300Details
BioGPS NCI60204617_s_atHOP92381.129594.300Details
BioGPS NCI60204617_s_atHS578T502.275594.300Details
BioGPS NCI60204617_s_atHSG546.071594.300Details
BioGPS NCI60204617_s_atHT1080261.848594.300Details
BioGPS NCI60204617_s_atHT29718.312594.300Details
BioGPS NCI60204617_s_atIGROV1590.147594.300Details
BioGPS NCI60204617_s_atIOSE801061.249594.300Details
BioGPS NCI60204617_s_atJURKAT935.548594.300Details
BioGPS NCI60204617_s_atK562366.495594.300Details
BioGPS NCI60204617_s_atKM121468.849594.300Details
BioGPS NCI60204617_s_atLN18401.120594.300Details
BioGPS NCI60204617_s_atLNCAP297.821594.300Details
BioGPS NCI60204617_s_atLOX IMVI428.772594.300Details
BioGPS NCI60204617_s_atM14617.521594.300Details
BioGPS NCI60204617_s_atMALME 3M108.645594.300Details
BioGPS NCI60204617_s_atMCF7589.359594.300Details
BioGPS NCI60204617_s_atMD MB231540.838594.300Details
BioGPS NCI60204617_s_atMDA MB4351282.807594.300Details
BioGPS NCI60204617_s_atMOLT41153.758594.300Details
BioGPS NCI60204617_s_atNCI 460638.323594.300Details
BioGPS NCI60204617_s_atNCI H226430.671594.300Details
BioGPS NCI60204617_s_atNCI H23496.624594.300Details
BioGPS NCI60204617_s_atNCI H322M685.686594.300Details
BioGPS NCI60204617_s_atNCVADR RES898.372594.300Details
BioGPS NCI60204617_s_atOVCAR31534.179594.300Details
BioGPS NCI60204617_s_atOVCAR4140.769594.300Details
BioGPS NCI60204617_s_atOVCAR5581.695594.300Details
BioGPS NCI60204617_s_atOVCAR8704.589594.300Details
BioGPS NCI60204617_s_atPANC1304.807594.300Details
BioGPS NCI60204617_s_atRL7661.075594.300Details
BioGPS NCI60204617_s_atRPMI 8226757.549594.300Details
BioGPS NCI60204617_s_atRS11846399.151594.300Details
BioGPS NCI60204617_s_atRXF393385.057594.300Details
BioGPS NCI60204617_s_atSAOS2171.442594.300Details
BioGPS NCI60204617_s_atSF268387.215594.300Details
BioGPS NCI60204617_s_atSF2951106.290594.300Details
BioGPS NCI60204617_s_atSF539398.444594.300Details
BioGPS NCI60204617_s_atSHSYSY+RA866.381594.300Details
BioGPS NCI60204617_s_atSHSYSY-RA682.433594.300Details
BioGPS NCI60204617_s_atSKMEL2630.758594.300Details
BioGPS NCI60204617_s_atSKMEL28187.359594.300Details
BioGPS NCI60204617_s_atSKMEL5288.348594.300Details
BioGPS NCI60204617_s_atSKOV31153.002594.300Details
BioGPS NCI60204617_s_atSN12C1169.300594.300Details
BioGPS NCI60204617_s_atSNB191003.065594.300Details
BioGPS NCI60204617_s_atSNB75169.006594.300Details
BioGPS NCI60204617_s_atSR1201.841594.300Details
BioGPS NCI60204617_s_atSW6201853.451594.300Details
BioGPS NCI60204617_s_atT241276.628594.300Details
BioGPS NCI60204617_s_atT3M4582.480594.300Details
BioGPS NCI60204617_s_atTK10318.080594.300Details
BioGPS NCI60204617_s_atU118473.957594.300Details
BioGPS NCI60204617_s_atU138582.357594.300Details
BioGPS NCI60204617_s_atU20S568.212594.300Details
BioGPS NCI60204617_s_atU251563.412594.300Details
BioGPS NCI60204617_s_atU87308.046594.300Details
BioGPS NCI60204617_s_atUACC257270.566594.300Details
BioGPS NCI60204617_s_atUACC62244.380594.300Details
BioGPS NCI60204617_s_atUO311011.057594.300Details
BioGPS NCI60204617_s_atZR75_1295.728594.300Details
BioGPS NCI60204617_s_atastrocytes351.656594.300Details
BioGPS NCI60204617_s_athuh-7544.428594.300Details