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Gene ID: 36 | ACADSB Antibody Resource


ACADSB Antibody Resource
Gene Full Name: 
acyl-CoA dehydrogenase, short/branched chain
Uniprot: 
P45954
Protein Name: 
short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
Nucleotide: 
NM_001609
Alias: 
ACAD7;SBCAD;2-MEBCAD;
Ensembl: 
ENSG00000196177
Location: 
10q26.13
HPRD: 
02626
NCBI Gene: 
36
MIM: 
600301

Summary: 
Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa. [provided by RefSeq, Jul 2008]
Function: 
Has greatest activity toward short branched chain acyl-CoA derivative such as (s)-2-methylbutyryl-CoA, isobutyryl-CoA, and 2-methylhexanoyl-CoA as well as toward short straight chain acyl-CoAs such as butyryl-CoA and hexanoyl-CoA. Can use valproyl-CoA as substrate and may play a role in controlling the metabolic flux of valproic acid in the development of toxicity of this agent.
Subcellular location: 
Mitochondrion matrix.
PTM: 
Acetylation;
Disease: 
Short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD) [MIM:610006]: Autosomal recessive disorder and consists of a defect in catabolism of L-isoleucine which is characterized by an increase of 2-methylbutyrylglycine and 2-methylbutyrylcarnitine in blood and urine. Affected individuals have seizures and psychomotor delay as the main clinical features. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP54586_P050 ACADSB antibody - middle region (ARP54586_P050) Polyclonal Dog, Guinea pig, Human, Mouse, Pig, Rabbit, Zebrafish WB 50ug $289 Details
Polyclonal Antibody OAAB05129 ACADSB antibody - C-terminal region (OAAB05129) Human WB, IHC, FC, ELISA 400ul $289 Details

Show all ACADSB antibodies


Product Images
ACADSB antibody - middle region (ARP54586_P050) in Human Liver cells using Western Blot

Sample Type: Human Liver


ACADSB Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP54586 Bovine ACADSB antibody; Bos taurus ACADSB antibody Q5EAD4 100.0%
ARP54586 Cat ACADSB antibody; Felis catus ACADSB antibody M3W0B5 100.0%
ARP54586 Chicken ACADSB antibody; Gallus gallus ACADSB antibody F1NZ81 79.0%
ARP54586 Chimpanzee ACADSB antibody; Pan troglodytes ACADSB antibody H2R3G8 100.0%
ARP54586 Chimpanzee ACADSB antibody; Pan troglodytes ACADSB antibody K7A158 100.0%
ARP54586 Collared flycatcher ACADSB antibody; Ficedula albicollis ACADSB antibody U3JQ67 79.0%
ARP54586 Dog ACADSB antibody; Canis familiaris ACADSB antibody F1PP63 86.0%
ARP54586 Domestic duck ACADSB antibody; Anas platyrhynchos ACADSB antibody U3J671 79.0%
ARP54586 European domestic ferret ACADSB antibody; Mustela putorius furo ACADSB antibody M3XUK5 93.0%
ARP54586 European seabass ACADSB antibody; Dicentrarchus labrax ACADSB antibody E6ZHL3 93.0%
ARP54586 Giant panda ACADSB antibody; Ailuropoda melanoleuca ACADSB antibody G1LDC9 100.0%
ARP54586 Gray short-tailed opossum ACADSB antibody; Monodelphis domestica ACADSB antibody F7A998 93.0%
ARP54586 Guinea pig ACADSB antibody; Cavia porcellus ACADSB antibody H0VLA5 93.0%
ARP54586 Guinea pig ACADSB antibody; Cavia porcellus ACADSB antibody H0VZ95 93.0%
ARP54586 Human ACADSB antibody; Homo sapiens ACADSB antibody B4DQ51 100.0%
ARP54586 Human ACADSB antibody; Homo sapiens ACADSB antibody P45954 100.0%
ARP54586 Mouse ACADSB antibody; Mus musculus ACADSB antibody Q3V2R9 100.0%
ARP54586 Mouse ACADSB antibody; Mus musculus ACADSB antibody Q7TMY2 100.0%
ARP54586 Mouse ACADSB antibody; Mus musculus ACADSB antibody Q9DBL1 100.0%
ARP54586 Mouse ACADSB antibody; Mus musculus ACADSB antibody E9Q5L3 100.0%
ARP54586 Northern white-cheeked gibbon ACADSB antibody; Nomascus leucogenys ACADSB antibody M3ZAY9 100.0%
ARP54586 Pig ACADSB antibody; Sus scrofa ACADSB antibody F1SED0 86.0%
ARP54586 Rabbit ACADSB antibody; Oryctolagus cuniculus ACADSB antibody G1SNP9 93.0%
ARP54586 Rat ACADSB antibody; Rattus norvegicus ACADSB antibody P70584 100.0%
ARP54586 Rhesus macaque ACADSB antibody; Macaca mulatta ACADSB antibody F6Z097 100.0%
ARP54586 Rhesus macaque ACADSB antibody; Macaca mulatta ACADSB antibody G7N1B7 100.0%
ARP54586 Small-eared galago ACADSB antibody; Otolemur garnettii ACADSB antibody H0WZ28 93.0%
ARP54586 Sumatran orangutan ACADSB antibody; Pongo abelii ACADSB antibody Q5RF40 100.0%
ARP54586 Sumatran orangutan ACADSB antibody; Pongo abelii ACADSB antibody H2NBV8 100.0%
ARP54586 Sumatran orangutan ACADSB antibody; Pongo abelii ACADSB antibody K7EU82 100.0%
ARP54586 Tasmanian devil ACADSB antibody; Sarcophilus harrisii ACADSB antibody G3VCY3 93.0%
ARP54586 Thirteen-lined ground squirrel ACADSB antibody; Spermophilus tridecemlineatus ACADSB antibody I3M8V7 100.0%
ARP54586 Western clawed frog ACADSB antibody; Xenopus tropicalis ACADSB antibody Q28FB8 93.0%
ARP54586 Western clawed frog ACADSB antibody; Xenopus tropicalis ACADSB antibody Q6DJ59 93.0%
ARP54586 Western clawed frog ACADSB antibody; Xenopus tropicalis ACADSB antibody F6VPL3 93.0%
ARP54586 Western clawed frog ACADSB antibody; Xenopus tropicalis ACADSB antibody F7BU71 93.0%
ARP54586 White-tufted-ear marmoset ACADSB antibody; Callithrix jacchus ACADSB antibody U3ELJ1 86.0%
ARP54586 White-tufted-ear marmoset ACADSB antibody; Callithrix jacchus ACADSB antibody F6YCA9 86.0%
ARP54586 White-tufted-ear marmoset ACADSB antibody; Callithrix jacchus ACADSB antibody F6YCH0 86.0%
ARP54586 White-tufted-ear marmoset ACADSB antibody; Callithrix jacchus ACADSB antibody F7IA04 86.0%
ARP54586 White-tufted-ear marmoset ACADSB antibody; Callithrix jacchus ACADSB antibody F7ISD2 86.0%
ARP54586 Zebra finch ACADSB antibody; Taeniopygia guttata ACADSB antibody H0ZM99 79.0%
ARP54586 Zebrafish ACADSB antibody; Danio rerio ACADSB antibody F1QFQ7 79.0%
ARP54586 Zebrafish ACADSB antibody; Danio rerio ACADSB antibody F8W3E0 79.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas205355_at721_B_lymphoblasts14.90019.060Details
BioGPS Gene Atlas205355_atAdipocyte13.00019.060Details
BioGPS Gene Atlas205355_atAdrenalCortex23.35019.060Details
BioGPS Gene Atlas205355_atAdrenalgland12.00019.060Details
BioGPS Gene Atlas205355_atAmygdala12.70019.060Details
BioGPS Gene Atlas205355_atAppendix25.45019.060Details
BioGPS Gene Atlas205355_atAtrioventricularNode26.65019.060Details
BioGPS Gene Atlas205355_atBDCA4+_DentriticCells11.20019.060Details
BioGPS Gene Atlas205355_atBonemarrow13.95019.060Details
BioGPS Gene Atlas205355_atBronchialEpithelialCells13.20019.060Details
BioGPS Gene Atlas205355_atCD105+_Endothelial32.55019.060Details
BioGPS Gene Atlas205355_atCD14+_Monocytes14.70019.060Details
BioGPS Gene Atlas205355_atCD19+_BCells(neg._sel.)15.50019.060Details
BioGPS Gene Atlas205355_atCD33+_Myeloid18.25019.060Details
BioGPS Gene Atlas205355_atCD34+15.85019.060Details
BioGPS Gene Atlas205355_atCD4+_Tcells14.15019.060Details
BioGPS Gene Atlas205355_atCD56+_NKCells15.20019.060Details
BioGPS Gene Atlas205355_atCD71+_EarlyErythroid12.85019.060Details
BioGPS Gene Atlas205355_atCD8+_Tcells11.65019.060Details
BioGPS Gene Atlas205355_atCardiacMyocytes30.90019.060Details
BioGPS Gene Atlas205355_atCaudatenucleus11.25019.060Details
BioGPS Gene Atlas205355_atCerebellum10.25019.060Details
BioGPS Gene Atlas205355_atCerebellumPeduncles20.75019.060Details
BioGPS Gene Atlas205355_atCiliaryGanglion21.65019.060Details
BioGPS Gene Atlas205355_atCingulateCortex15.90019.060Details
BioGPS Gene Atlas205355_atColorectaladenocarcinoma11.85019.060Details
BioGPS Gene Atlas205355_atDorsalRootGanglion20.35019.060Details
BioGPS Gene Atlas205355_atFetalThyroid13.50019.060Details
BioGPS Gene Atlas205355_atFetalbrain12.50019.060Details
BioGPS Gene Atlas205355_atFetalliver224.35019.060Details
BioGPS Gene Atlas205355_atFetallung10.40019.060Details
BioGPS Gene Atlas205355_atGlobusPallidus13.10019.060Details
BioGPS Gene Atlas205355_atHeart25.95019.060Details
BioGPS Gene Atlas205355_atHypothalamus13.50019.060Details
BioGPS Gene Atlas205355_atKidney13.70019.060Details
BioGPS Gene Atlas205355_atLeukemia_chronicMyelogenousK-56213.80019.060Details
BioGPS Gene Atlas205355_atLeukemia_promyelocytic-HL-6012.10019.060Details
BioGPS Gene Atlas205355_atLeukemialymphoblastic(MOLT-4)10.05019.060Details
BioGPS Gene Atlas205355_atLiver22.60019.060Details
BioGPS Gene Atlas205355_atLung13.50019.060Details
BioGPS Gene Atlas205355_atLymphnode9.65019.060Details
BioGPS Gene Atlas205355_atLymphoma_burkitts(Daudi)17.60019.060Details
BioGPS Gene Atlas205355_atLymphoma_burkitts(Raji)20.50019.060Details
BioGPS Gene Atlas205355_atMedullaOblongata11.55019.060Details
BioGPS Gene Atlas205355_atOccipitalLobe11.50019.060Details
BioGPS Gene Atlas205355_atOlfactoryBulb10.35019.060Details
BioGPS Gene Atlas205355_atOvary12.90019.060Details
BioGPS Gene Atlas205355_atPancreas12.90019.060Details
BioGPS Gene Atlas205355_atPancreaticIslet24.50019.060Details
BioGPS Gene Atlas205355_atParietalLobe15.05019.060Details
BioGPS Gene Atlas205355_atPituitary16.60019.060Details
BioGPS Gene Atlas205355_atPlacenta10.95019.060Details
BioGPS Gene Atlas205355_atPons17.50019.060Details
BioGPS Gene Atlas205355_atPrefrontalCortex14.25019.060Details
BioGPS Gene Atlas205355_atProstate26.10019.060Details
BioGPS Gene Atlas205355_atSalivarygland14.10019.060Details
BioGPS Gene Atlas205355_atSkeletalMuscle31.35019.060Details
BioGPS Gene Atlas205355_atSkin20.55019.060Details
BioGPS Gene Atlas205355_atSmoothMuscle14.55019.060Details
BioGPS Gene Atlas205355_atSpinalcord13.70019.060Details
BioGPS Gene Atlas205355_atSubthalamicNucleus16.30019.060Details
BioGPS Gene Atlas205355_atSuperiorCervicalGanglion29.75019.060Details
BioGPS Gene Atlas205355_atTemporalLobe13.10019.060Details
BioGPS Gene Atlas205355_atTestis11.45019.060Details
BioGPS Gene Atlas205355_atTestisGermCell14.10019.060Details
BioGPS Gene Atlas205355_atTestisIntersitial15.65019.060Details
BioGPS Gene Atlas205355_atTestisLeydigCell14.70019.060Details
BioGPS Gene Atlas205355_atTestisSeminiferousTubule12.05019.060Details
BioGPS Gene Atlas205355_atThalamus13.35019.060Details
BioGPS Gene Atlas205355_atThymus8.25019.060Details
BioGPS Gene Atlas205355_atThyroid15.75019.060Details
BioGPS Gene Atlas205355_atTongue21.30019.060Details
BioGPS Gene Atlas205355_atTonsil13.55019.060Details
BioGPS Gene Atlas205355_atTrachea10.85019.060Details
BioGPS Gene Atlas205355_atTrigeminalGanglion79.50019.060Details
BioGPS Gene Atlas205355_atUterus10.00019.060Details
BioGPS Gene Atlas205355_atUterusCorpus19.20019.060Details
BioGPS Gene Atlas205355_atWholeBlood12.90019.060Details
BioGPS Gene Atlas205355_atWholebrain7.75019.060Details
BioGPS Gene Atlas205355_atcolon17.50019.060Details
BioGPS Gene Atlas205355_atpineal_day18.44019.060Details
BioGPS Gene Atlas205355_atpineal_night16.14019.060Details
BioGPS Gene Atlas205355_atretina15.65019.060Details
BioGPS Gene Atlas205355_atsmall_intestine17.05019.060Details
BioGPS NCI60205355_at78646.19140.890Details
BioGPS NCI60205355_atA17217.49740.890Details
BioGPS NCI60205355_atA20419.65040.890Details
BioGPS NCI60205355_atA36120.04440.890Details
BioGPS NCI60205355_atA49815.41440.890Details
BioGPS NCI60205355_atA54922.39440.890Details
BioGPS NCI60205355_atACC322.97440.890Details
BioGPS NCI60205355_atACHN18.62840.890Details
BioGPS NCI60205355_atALVA3153.43240.890Details
BioGPS NCI60205355_atCAKI124.51340.890Details
BioGPS NCI60205355_atCCRT CEM39.67540.890Details
BioGPS NCI60205355_atCOLO20521.63540.890Details
BioGPS NCI60205355_atDLD120.93940.890Details
BioGPS NCI60205355_atDU14513.95640.890Details
BioGPS NCI60205355_atEKVX19.74240.890Details
BioGPS NCI60205355_atGM133187.19940.890Details
BioGPS NCI60205355_atGM160041.73340.890Details
BioGPS NCI60205355_atGM231323.26140.890Details
BioGPS NCI60205355_atGM234521.51140.890Details
BioGPS NCI60205355_atGM249348.28640.890Details
BioGPS NCI60205355_atGM9755.50640.890Details
BioGPS NCI60205355_atHCC299818.83940.890Details
BioGPS NCI60205355_atHCT11622.01840.890Details
BioGPS NCI60205355_atHCT1525.06440.890Details
BioGPS NCI60205355_atHEK 293 T-rex96.60640.890Details
BioGPS NCI60205355_atHEK 293T21.59440.890Details
BioGPS NCI60205355_atHEK293297.80640.890Details
BioGPS NCI60205355_atHELA12.99640.890Details
BioGPS NCI60205355_atHEPG278.26240.890Details
BioGPS NCI60205355_atHL6033.48640.890Details
BioGPS NCI60205355_atHOP6219.28440.890Details
BioGPS NCI60205355_atHOP9215.97740.890Details
BioGPS NCI60205355_atHS578T18.16040.890Details
BioGPS NCI60205355_atHSG12.09340.890Details
BioGPS NCI60205355_atHT108019.83340.890Details
BioGPS NCI60205355_atHT2925.43640.890Details
BioGPS NCI60205355_atIGROV152.16340.890Details
BioGPS NCI60205355_atIOSE8020.51040.890Details
BioGPS NCI60205355_atJURKAT30.07340.890Details
BioGPS NCI60205355_atK56223.96440.890Details
BioGPS NCI60205355_atKM1222.73240.890Details
BioGPS NCI60205355_atLN1898.28440.890Details
BioGPS NCI60205355_atLNCAP304.96740.890Details
BioGPS NCI60205355_atLOX IMVI19.26340.890Details
BioGPS NCI60205355_atM1421.15740.890Details
BioGPS NCI60205355_atMALME 3M27.84740.890Details
BioGPS NCI60205355_atMCF750.51940.890Details
BioGPS NCI60205355_atMD MB23122.63140.890Details
BioGPS NCI60205355_atMDA MB43541.67340.890Details
BioGPS NCI60205355_atMOLT422.53240.890Details
BioGPS NCI60205355_atNCI 46069.02440.890Details
BioGPS NCI60205355_atNCI H22623.04640.890Details
BioGPS NCI60205355_atNCI H2319.17440.890Details
BioGPS NCI60205355_atNCI H322M84.61340.890Details
BioGPS NCI60205355_atNCVADR RES12.16040.890Details
BioGPS NCI60205355_atOVCAR335.13740.890Details
BioGPS NCI60205355_atOVCAR417.43440.890Details
BioGPS NCI60205355_atOVCAR514.75940.890Details
BioGPS NCI60205355_atOVCAR811.23940.890Details
BioGPS NCI60205355_atPANC1140.83640.890Details
BioGPS NCI60205355_atRL722.00640.890Details
BioGPS NCI60205355_atRPMI 822619.19740.890Details
BioGPS NCI60205355_atRS1184626.80740.890Details
BioGPS NCI60205355_atRXF39321.04940.890Details
BioGPS NCI60205355_atSAOS218.24640.890Details
BioGPS NCI60205355_atSF26825.93540.890Details
BioGPS NCI60205355_atSF29512.97640.890Details
BioGPS NCI60205355_atSF53917.11440.890Details
BioGPS NCI60205355_atSHSYSY+RA14.80940.890Details
BioGPS NCI60205355_atSHSYSY-RA16.44140.890Details
BioGPS NCI60205355_atSKMEL268.73440.890Details
BioGPS NCI60205355_atSKMEL2891.21340.890Details
BioGPS NCI60205355_atSKMEL523.13540.890Details
BioGPS NCI60205355_atSKOV331.39940.890Details
BioGPS NCI60205355_atSN12C21.34440.890Details
BioGPS NCI60205355_atSNB1929.58540.890Details
BioGPS NCI60205355_atSNB7515.68040.890Details
BioGPS NCI60205355_atSR23.30740.890Details
BioGPS NCI60205355_atSW62026.25540.890Details
BioGPS NCI60205355_atT2419.25240.890Details
BioGPS NCI60205355_atT3M422.63440.890Details
BioGPS NCI60205355_atTK1016.25240.890Details
BioGPS NCI60205355_atU11819.75240.890Details
BioGPS NCI60205355_atU13819.02640.890Details
BioGPS NCI60205355_atU20S18.02340.890Details
BioGPS NCI60205355_atU25117.22740.890Details
BioGPS NCI60205355_atU8719.65440.890Details
BioGPS NCI60205355_atUACC25714.56140.890Details
BioGPS NCI60205355_atUACC6221.69240.890Details
BioGPS NCI60205355_atUO3119.87640.890Details
BioGPS NCI60205355_atZR75_136.67540.890Details
BioGPS NCI60205355_atastrocytes21.88340.890Details
BioGPS NCI60205355_athuh-7119.62840.890Details