Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 1244 | Abcc2 Antibody Resource


Abcc2 Antibody Resource
Gene Full Name: 
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Uniprot: 
Q92887
Protein Name: 
canalicular multispecific organic anion transporter 1
Nucleotide: 
XM_005269536
Alias: 
DJS;MRP2;cMRP;ABC30;CMOAT;
Ensembl: 
ENSG00000023839
Location: 
10q24
HPRD: 
03065
NCBI Gene: 
1244
MIM: 
601107

Summary: 
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq, Jul 2008]
Function: 
Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.
Subcellular location: 
Membrane; Multi-pass membrane protein.
PTM: 
Glycoprotein;
Disease: 
Dubin-Johnson syndrome (DJS) [MIM:237500]: Autosomal recessive disorder characterized by conjugated hyperbilirubinemia, an increase in the urinary excretion of coproporphyrin isomer I, deposition of melanin-like pigment in hepatocytes, and prolonged retention of sulfobromophthalein, but otherwise normal liver function. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP43624_P050 Abcc2 antibody - middle region (ARP43624_P050) Polyclonal Bovine, Dog, Horse, Mouse WB 50ug $289 Details
Polyclonal Antibody ARP43625_P050 ABCC2 Antibody (ARP43625_P050) Polyclonal Bovine, Dog, Guinea pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish Not tested 50 ug $125 Details
Polyclonal Antibody OAAF03415 ABCC2 Antibody (OAAF03415) Polyclonal Human WB, ELISA 100 ug $229 Details

Show all Abcc2 antibodies


Product Images
Abcc2 antibody - middle region (ARP43624_P050) in Mouse Spleen cells using Western Blot

Sample Type: Mouse Spleen

ABCC2 Antibody (OAAF03415) in RAW264.7 cells using Western Blot

Sample Type: RAW264.7


Abcc2 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP43624 African elephant Abcc2 antibody; Loxodonta africana Abcc2 antibody G3TD25 93.0%
ARP43625 African elephant Abcc2 antibody; Loxodonta africana Abcc2 antibody G3TD25 86.0%
ARP43625 Bovine Abcc2 antibody; Bos taurus Abcc2 antibody F1MIP7 100.0%
ARP43624 Bovine Abcc2 antibody; Bos taurus Abcc2 antibody F1MIP7 79.0%
ARP43624 Cat Abcc2 antibody; Felis catus Abcc2 antibody M3WKM0 93.0%
ARP43625 Cat Abcc2 antibody; Felis catus Abcc2 antibody M3WKM0 86.0%
ARP43625 Chicken Abcc2 antibody; Gallus gallus Abcc2 antibody E1C6S5 86.0%
ARP43625 Chub Abcc2 antibody; Squalius cephalus Abcc2 antibody C3VPX1 85.0%
ARP43625 Common turkey Abcc2 antibody; Meleagris gallopavo Abcc2 antibody G1NB22 86.0%
ARP43625 Common turkey Abcc2 antibody; Meleagris gallopavo Abcc2 antibody Q5I3Q1 86.0%
ARP43624 Crab-eating macaque Abcc2 antibody; Macaca fascicularis Abcc2 antibody A5GZW6 100.0%
ARP43625 Crab-eating macaque Abcc2 antibody; Macaca fascicularis Abcc2 antibody A5GZW6 93.0%
ARP43624 Dog Abcc2 antibody; Canis familiaris Abcc2 antibody F1PHV0 86.0%
ARP43625 Dog Abcc2 antibody; Canis familiaris Abcc2 antibody F1PHV0 86.0%
ARP43625 Domestic duck Abcc2 antibody; Anas platyrhynchos Abcc2 antibody U3IML7 86.0%
ARP43624 European domestic ferret Abcc2 antibody; Mustela putorius furo Abcc2 antibody M3YZW9 86.0%
ARP43625 European domestic ferret Abcc2 antibody; Mustela putorius furo Abcc2 antibody M3YZW9 86.0%
ARP43625 European seabass Abcc2 antibody; Dicentrarchus labrax Abcc2 antibody F8QMV2 83.0%
ARP43624 Giant panda Abcc2 antibody; Ailuropoda melanoleuca Abcc2 antibody G1LKV8 86.0%
ARP43625 Giant panda Abcc2 antibody; Ailuropoda melanoleuca Abcc2 antibody G1LKV8 86.0%
ARP56790 Gray short-tailed opossum Abcc2 antibody; Monodelphis domestica Abcc2 antibody F6Z127 86.0%
ARP43625 Gray short-tailed opossum Abcc2 antibody; Monodelphis domestica Abcc2 antibody F6Z127 79.0%
ARP43624 Horse Abcc2 antibody; Equus caballus Abcc2 antibody F6VW89 93.0%
ARP43624 Horse Abcc2 antibody; Equus caballus Abcc2 antibody F6W3C2 93.0%
ARP43625 Horse Abcc2 antibody; Equus caballus Abcc2 antibody F6VW89 92.0%
ARP43625 Horse Abcc2 antibody; Equus caballus Abcc2 antibody F6W3C2 92.0%
ARP43624 Human Abcc2 antibody; Homo sapiens Abcc2 antibody Q92887 100.0%
ARP43625 Human Abcc2 antibody; Homo sapiens Abcc2 antibody Q92887 100.0%
ARP43625 Mouse Abcc2 antibody; Mus musculus Abcc2 antibody Q8VI47 92.0%
ARP43625 Mouse Abcc2 antibody; Mus musculus Abcc2 antibody Q9JIH8 92.0%
ARP43624 Mouse Abcc2 antibody; Mus musculus Abcc2 antibody Q9JIH8 86.0%
ARP43624 Mouse Abcc2 antibody; Mus musculus Abcc2 antibody Q8VI47 86.0%
ARP43664 Mouse-ear cress Abcc2 antibody; Arabidopsis thaliana Abcc2 antibody Q42093 86.0%
ARP43625 Nile tilapia Abcc2 antibody; Oreochromis niloticus Abcc2 antibody G4V2D0 85.0%
ARP43625 Pig Abcc2 antibody; Sus scrofa Abcc2 antibody F1S8V9 92.0%
ARP43624 Rabbit Abcc2 antibody; Oryctolagus cuniculus Abcc2 antibody Q28689 100.0%
ARP43625 Rabbit Abcc2 antibody; Oryctolagus cuniculus Abcc2 antibody Q28689 93.0%
ARP43625 Rat Abcc2 antibody; Rattus norvegicus Abcc2 antibody Q63120 92.0%
ARP43624 Rat Abcc2 antibody; Rattus norvegicus Abcc2 antibody Q63120 86.0%
ARP43624 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody F7GVK9 100.0%
ARP43624 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody F7GVL3 100.0%
ARP43625 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody F7GVL3 93.0%
ARP43625 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody H9F6I0 93.0%
ARP43624 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody Q4U3V2 93.0%
ARP43625 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody Q4U3V2 93.0%
ARP43625 Rhesus macaque Abcc2 antibody; Macaca mulatta Abcc2 antibody F7GVK9 93.0%
ARP43624 Small-eared galago Abcc2 antibody; Otolemur garnettii Abcc2 antibody H0WIX5 86.0%
ARP43625 Small-eared galago Abcc2 antibody; Otolemur garnettii Abcc2 antibody H0WIX5 86.0%
ARP43625 Spotted green pufferfish Abcc2 antibody; Tetraodon nigroviridis Abcc2 antibody H3DGG8 83.0%
ARP43625 Sumatran orangutan Abcc2 antibody; Pongo abelii Abcc2 antibody H2NB99 100.0%
ARP43625 Sumatran orangutan Abcc2 antibody; Pongo abelii Abcc2 antibody K7ESY5 100.0%
ARP43624 Sumatran orangutan Abcc2 antibody; Pongo abelii Abcc2 antibody H2NB99 93.0%
ARP43624 Sumatran orangutan Abcc2 antibody; Pongo abelii Abcc2 antibody K7ESY5 93.0%
ARP43625 Tasmanian devil Abcc2 antibody; Sarcophilus harrisii Abcc2 antibody G3WEA3 86.0%
ARP43624 Thirteen-lined ground squirrel Abcc2 antibody; Spermophilus tridecemlineatus Abcc2 antibody I3ME26 100.0%
ARP43625 Thirteen-lined ground squirrel Abcc2 antibody; Spermophilus tridecemlineatus Abcc2 antibody I3ME26 92.0%
ARP43625 Western clawed frog Abcc2 antibody; Xenopus tropicalis Abcc2 antibody F6TR94 79.0%
ARP43719 Western clawed frog Abcc2 antibody; Xenopus tropicalis Abcc2 antibody F6TR94 79.0%
ARP43624 White-tufted-ear marmoset Abcc2 antibody; Callithrix jacchus Abcc2 antibody F7HYI2 100.0%
ARP43625 White-tufted-ear marmoset Abcc2 antibody; Callithrix jacchus Abcc2 antibody F7HYI2 100.0%

Tissue & Cell Line Gene Expression Data
Data SourceProbesetSampleAvgMeanMore Info
BioGPS Gene Atlas206155_at721_B_lymphoblasts7.0506.890Details
BioGPS Gene Atlas206155_atAdipocyte11.2006.890Details
BioGPS Gene Atlas206155_atAdrenalCortex7.2006.890Details
BioGPS Gene Atlas206155_atAdrenalgland5.2506.890Details
BioGPS Gene Atlas206155_atAmygdala6.2506.890Details
BioGPS Gene Atlas206155_atAppendix6.5006.890Details
BioGPS Gene Atlas206155_atAtrioventricularNode5.4506.890Details
BioGPS Gene Atlas206155_atBDCA4+_DentriticCells6.2006.890Details
BioGPS Gene Atlas206155_atBonemarrow6.3506.890Details
BioGPS Gene Atlas206155_atBronchialEpithelialCells6.0006.890Details
BioGPS Gene Atlas206155_atCD105+_Endothelial5.9006.890Details
BioGPS Gene Atlas206155_atCD14+_Monocytes6.4506.890Details
BioGPS Gene Atlas206155_atCD19+_BCells(neg._sel.)6.4006.890Details
BioGPS Gene Atlas206155_atCD33+_Myeloid7.4506.890Details
BioGPS Gene Atlas206155_atCD34+7.4506.890Details
BioGPS Gene Atlas206155_atCD4+_Tcells6.2006.890Details
BioGPS Gene Atlas206155_atCD56+_NKCells6.6006.890Details
BioGPS Gene Atlas206155_atCD71+_EarlyErythroid5.8006.890Details
BioGPS Gene Atlas206155_atCD8+_Tcells5.4006.890Details
BioGPS Gene Atlas206155_atCardiacMyocytes8.2506.890Details
BioGPS Gene Atlas206155_atCaudatenucleus5.5006.890Details
BioGPS Gene Atlas206155_atCerebellum8.0006.890Details
BioGPS Gene Atlas206155_atCerebellumPeduncles7.1506.890Details
BioGPS Gene Atlas206155_atCiliaryGanglion4.8006.890Details
BioGPS Gene Atlas206155_atCingulateCortex6.3506.890Details
BioGPS Gene Atlas206155_atColorectaladenocarcinoma5.9506.890Details
BioGPS Gene Atlas206155_atDorsalRootGanglion5.1006.890Details
BioGPS Gene Atlas206155_atFetalThyroid5.9506.890Details
BioGPS Gene Atlas206155_atFetalbrain6.2506.890Details
BioGPS Gene Atlas206155_atFetalliver15.1506.890Details
BioGPS Gene Atlas206155_atFetallung12.9506.890Details
BioGPS Gene Atlas206155_atGlobusPallidus4.6006.890Details
BioGPS Gene Atlas206155_atHeart8.0506.890Details
BioGPS Gene Atlas206155_atHypothalamus6.5006.890Details
BioGPS Gene Atlas206155_atKidney9.4506.890Details
BioGPS Gene Atlas206155_atLeukemia_chronicMyelogenousK-5625.6006.890Details
BioGPS Gene Atlas206155_atLeukemia_promyelocytic-HL-605.5006.890Details
BioGPS Gene Atlas206155_atLeukemialymphoblastic(MOLT-4)4.8506.890Details
BioGPS Gene Atlas206155_atLiver8.8506.890Details
BioGPS Gene Atlas206155_atLung7.0506.890Details
BioGPS Gene Atlas206155_atLymphnode5.9506.890Details
BioGPS Gene Atlas206155_atLymphoma_burkitts(Daudi)8.0006.890Details
BioGPS Gene Atlas206155_atLymphoma_burkitts(Raji)9.1506.890Details
BioGPS Gene Atlas206155_atMedullaOblongata5.6506.890Details
BioGPS Gene Atlas206155_atOccipitalLobe5.5506.890Details
BioGPS Gene Atlas206155_atOlfactoryBulb5.3506.890Details
BioGPS Gene Atlas206155_atOvary4.3006.890Details
BioGPS Gene Atlas206155_atPancreas12.0506.890Details
BioGPS Gene Atlas206155_atPancreaticIslet23.1006.890Details
BioGPS Gene Atlas206155_atParietalLobe6.8006.890Details
BioGPS Gene Atlas206155_atPituitary7.2506.890Details
BioGPS Gene Atlas206155_atPlacenta6.4006.890Details
BioGPS Gene Atlas206155_atPons5.9506.890Details
BioGPS Gene Atlas206155_atPrefrontalCortex7.3506.890Details
BioGPS Gene Atlas206155_atProstate7.1006.890Details
BioGPS Gene Atlas206155_atSalivarygland5.2506.890Details
BioGPS Gene Atlas206155_atSkeletalMuscle8.6506.890Details
BioGPS Gene Atlas206155_atSkin5.2506.890Details
BioGPS Gene Atlas206155_atSmoothMuscle7.0006.890Details
BioGPS Gene Atlas206155_atSpinalcord6.6006.890Details
BioGPS Gene Atlas206155_atSubthalamicNucleus6.3006.890Details
BioGPS Gene Atlas206155_atSuperiorCervicalGanglion8.8506.890Details
BioGPS Gene Atlas206155_atTemporalLobe5.6006.890Details
BioGPS Gene Atlas206155_atTestis5.3506.890Details
BioGPS Gene Atlas206155_atTestisGermCell5.2006.890Details
BioGPS Gene Atlas206155_atTestisIntersitial5.2006.890Details
BioGPS Gene Atlas206155_atTestisLeydigCell6.2006.890Details
BioGPS Gene Atlas206155_atTestisSeminiferousTubule5.3006.890Details
BioGPS Gene Atlas206155_atThalamus6.3006.890Details
BioGPS Gene Atlas206155_atThymus4.8006.890Details
BioGPS Gene Atlas206155_atThyroid7.5006.890Details
BioGPS Gene Atlas206155_atTongue6.3506.890Details
BioGPS Gene Atlas206155_atTonsil6.0506.890Details
BioGPS Gene Atlas206155_atTrachea5.2006.890Details
BioGPS Gene Atlas206155_atTrigeminalGanglion6.8006.890Details
BioGPS Gene Atlas206155_atUterus4.9006.890Details
BioGPS Gene Atlas206155_atUterusCorpus5.9006.890Details
BioGPS Gene Atlas206155_atWholeBlood6.7506.890Details
BioGPS Gene Atlas206155_atWholebrain5.2506.890Details
BioGPS Gene Atlas206155_atcolon6.0506.890Details
BioGPS Gene Atlas206155_atpineal_day7.3206.890Details
BioGPS Gene Atlas206155_atpineal_night6.9206.890Details
BioGPS Gene Atlas206155_atretina7.4756.890Details
BioGPS Gene Atlas206155_atsmall_intestine6.0506.890Details
BioGPS NCI60206155_at7865.58670.860Details
BioGPS NCI60206155_atA1725.19770.860Details
BioGPS NCI60206155_atA204340.70570.860Details
BioGPS NCI60206155_atA36138.72170.860Details
BioGPS NCI60206155_atA498203.22070.860Details
BioGPS NCI60206155_atA549749.80070.860Details
BioGPS NCI60206155_atACC35.86870.860Details
BioGPS NCI60206155_atACHN5.10470.860Details
BioGPS NCI60206155_atALVA315.96370.860Details
BioGPS NCI60206155_atCAKI15.80770.860Details
BioGPS NCI60206155_atCCRT CEM7.15270.860Details
BioGPS NCI60206155_atCOLO205161.19870.860Details
BioGPS NCI60206155_atDLD15.48070.860Details
BioGPS NCI60206155_atDU1455.27370.860Details
BioGPS NCI60206155_atEKVX5.34870.860Details
BioGPS NCI60206155_atGM1335.62470.860Details
BioGPS NCI60206155_atGM16005.78470.860Details
BioGPS NCI60206155_atGM23135.63370.860Details
BioGPS NCI60206155_atGM23455.55670.860Details
BioGPS NCI60206155_atGM24935.89770.860Details
BioGPS NCI60206155_atGM976.46870.860Details
BioGPS NCI60206155_atHCC2998312.59870.860Details
BioGPS NCI60206155_atHCT11646.44370.860Details
BioGPS NCI60206155_atHCT155.18770.860Details
BioGPS NCI60206155_atHEK 293 T-rex5.72270.860Details
BioGPS NCI60206155_atHEK 293T5.61770.860Details
BioGPS NCI60206155_atHEK2935.46370.860Details
BioGPS NCI60206155_atHELA5.23970.860Details
BioGPS NCI60206155_atHEPG22551.27170.860Details
BioGPS NCI60206155_atHL606.78270.860Details
BioGPS NCI60206155_atHOP625.57070.860Details
BioGPS NCI60206155_atHOP925.36070.860Details
BioGPS NCI60206155_atHS578T5.47370.860Details
BioGPS NCI60206155_atHSG5.94970.860Details
BioGPS NCI60206155_atHT10805.43670.860Details
BioGPS NCI60206155_atHT296.01770.860Details
BioGPS NCI60206155_atIGROV15.49270.860Details
BioGPS NCI60206155_atIOSE805.50170.860Details
BioGPS NCI60206155_atJURKAT5.56370.860Details
BioGPS NCI60206155_atK5625.99670.860Details
BioGPS NCI60206155_atKM125.83770.860Details
BioGPS NCI60206155_atLN1851.50870.860Details
BioGPS NCI60206155_atLNCAP5.53970.860Details
BioGPS NCI60206155_atLOX IMVI5.52270.860Details
BioGPS NCI60206155_atM14472.26570.860Details
BioGPS NCI60206155_atMALME 3M5.95970.860Details
BioGPS NCI60206155_atMCF75.38570.860Details
BioGPS NCI60206155_atMD MB2315.61370.860Details
BioGPS NCI60206155_atMDA MB43510.70370.860Details
BioGPS NCI60206155_atMOLT45.96270.860Details
BioGPS NCI60206155_atNCI 460738.52370.860Details
BioGPS NCI60206155_atNCI H2265.69770.860Details
BioGPS NCI60206155_atNCI H235.51270.860Details
BioGPS NCI60206155_atNCI H322M79.24870.860Details
BioGPS NCI60206155_atNCVADR RES5.11670.860Details
BioGPS NCI60206155_atOVCAR35.77970.860Details
BioGPS NCI60206155_atOVCAR45.50670.860Details
BioGPS NCI60206155_atOVCAR55.40670.860Details
BioGPS NCI60206155_atOVCAR85.12970.860Details
BioGPS NCI60206155_atPANC15.49170.860Details
BioGPS NCI60206155_atRL75.62370.860Details
BioGPS NCI60206155_atRPMI 82265.67370.860Details
BioGPS NCI60206155_atRS118465.65470.860Details
BioGPS NCI60206155_atRXF3935.85970.860Details
BioGPS NCI60206155_atSAOS25.57370.860Details
BioGPS NCI60206155_atSF2685.56570.860Details
BioGPS NCI60206155_atSF2955.45870.860Details
BioGPS NCI60206155_atSF5395.17570.860Details
BioGPS NCI60206155_atSHSYSY+RA5.28370.860Details
BioGPS NCI60206155_atSHSYSY-RA5.42170.860Details
BioGPS NCI60206155_atSKMEL27.66070.860Details
BioGPS NCI60206155_atSKMEL285.63470.860Details
BioGPS NCI60206155_atSKMEL5490.85270.860Details
BioGPS NCI60206155_atSKOV35.59470.860Details
BioGPS NCI60206155_atSN12C5.51570.860Details
BioGPS NCI60206155_atSNB195.19670.860Details
BioGPS NCI60206155_atSNB755.50370.860Details
BioGPS NCI60206155_atSR5.60870.860Details
BioGPS NCI60206155_atSW6205.80670.860Details
BioGPS NCI60206155_atT245.48870.860Details
BioGPS NCI60206155_atT3M45.84070.860Details
BioGPS NCI60206155_atTK105.37170.860Details
BioGPS NCI60206155_atU11819.75570.860Details
BioGPS NCI60206155_atU1385.22270.860Details
BioGPS NCI60206155_atU20S5.39470.860Details
BioGPS NCI60206155_atU2515.47670.860Details
BioGPS NCI60206155_atU87120.54370.860Details
BioGPS NCI60206155_atUACC2575.48870.860Details
BioGPS NCI60206155_atUACC625.59670.860Details
BioGPS NCI60206155_atUO315.31570.860Details
BioGPS NCI60206155_atZR75_15.71470.860Details
BioGPS NCI60206155_atastrocytes5.68170.860Details
BioGPS NCI60206155_athuh-7271.55370.860Details