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Gene ID: 85320 | ABCC11 Antibody Resource


ABCC11 Antibody Resource
Gene Full Name: 
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
Uniprot: 
Q96J66
Protein Name: 
ATP-binding cassette sub-family C member 11
Nucleotide: 
XM_005256209
Alias: 
WW;EWWD;MRP8;
Ensembl: 
ENSG00000121270
Location: 
16q12.1
HPRD: 
06127
NCBI Gene: 
85320
MIM: 
607040

Summary: 
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Function: 
Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E217betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. Probably functions to secrete earwax.
Subcellular location: 
Membrane; Multi-pass membrane protein.
PTM: 
Glycoprotein;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP43719_P050 ABCC11 antibody - middle region (ARP43719_P050) Polyclonal Dog, Rabbit WB 50ug $289 Details
Polyclonal Antibody OAEB01859 Goat Anti-MRP8 / ABCC11 Antibody (OAEB01859) Bovine, Dog, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody OAAB02206 ABCC11 antibody - N-terminal region (OAAB02206) Human WB, IHC 400ul $289 Details
Polyclonal Antibody ARP43706_P050 ABCC11 Antibody (ARP43706_P050) Polyclonal Dog, Human, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody ARP43707_P050 ABCC11 Antibody (ARP43707_P050) Polyclonal Bovine, Dog, Horse, Human, Rabbit Not tested 50 ug $125 Details
Polyclonal Antibody ARP43718_P050 ABCC11 Antibody (ARP43718_P050) Polyclonal Dog, Horse, Human Not tested 50 ug $125 Details

Show all ABCC11 antibodies


Product Images
ABCC11 antibody - middle region (ARP43719_P050) in Human NCI-H226 cells using Western Blot

Sample Type: Human NCI-H226

ABCC11 antibody - N-terminal region (OAAB02206) in breast carcinoma cells using Immunohistochemistry

Sample Type: breast carcinoma

ABCC11 antibody - N-terminal region (OAAB02206) in WiDr cells using Western Blot

Sample Type: WiDr

Goat Anti-MRP8 / ABCC11 Antibody (OAEB01859) in Human Breast cells using Western Blot

Sample Type: Human Breast


ABCC11 Protocols

Publications

Related Gene Trend Categories

Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP43718 Cat ABCC11 antibody; Felis catus ABCC11 antibody M3W3T0 100.0%
ARP43719 Cat ABCC11 antibody; Felis catus ABCC11 antibody M3W3T0 93.0%
ARP43706 Cat ABCC11 antibody; Felis catus ABCC11 antibody M3W3T0 93.0%
ARP43707 Cat ABCC11 antibody; Felis catus ABCC11 antibody M3W3T0 79.0%
ARP43706 Chimpanzee ABCC11 antibody; Pan troglodytes ABCC11 antibody H2QZK4 100.0%
ARP43707 Chimpanzee ABCC11 antibody; Pan troglodytes ABCC11 antibody H2QZK4 100.0%
ARP43718 Chimpanzee ABCC11 antibody; Pan troglodytes ABCC11 antibody H2QZK4 100.0%
ARP43719 Chimpanzee ABCC11 antibody; Pan troglodytes ABCC11 antibody H2QZK4 100.0%
ARP43718 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody E2RBC4 100.0%
ARP43718 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody J9P6G2 100.0%
ARP43706 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody E2RBC4 86.0%
ARP43719 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody E2RBC4 86.0%
ARP43706 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody J9P6G2 86.0%
ARP43719 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody J9P6G2 86.0%
ARP43707 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody E2RBC4 79.0%
ARP43707 Dog ABCC11 antibody; Canis familiaris ABCC11 antibody J9P6G2 79.0%
ARP43718 Duckbill platypus ABCC11 antibody; Ornithorhynchus anatinus ABCC11 antibody F7BXT9 92.0%
ARP43719 Duckbill platypus ABCC11 antibody; Ornithorhynchus anatinus ABCC11 antibody F7BXT9 86.0%
ARP43707 Duckbill platypus ABCC11 antibody; Ornithorhynchus anatinus ABCC11 antibody F7BXT9 79.0%
ARP43718 European domestic ferret ABCC11 antibody; Mustela putorius furo ABCC11 antibody M3XV81 100.0%
ARP43706 European domestic ferret ABCC11 antibody; Mustela putorius furo ABCC11 antibody M3XV81 93.0%
ARP43719 European domestic ferret ABCC11 antibody; Mustela putorius furo ABCC11 antibody M3XV81 86.0%
ARP43707 European domestic ferret ABCC11 antibody; Mustela putorius furo ABCC11 antibody M3XV81 79.0%
ARP43706 Giant panda ABCC11 antibody; Ailuropoda melanoleuca ABCC11 antibody G1LCJ7 100.0%
ARP43719 Gray short-tailed opossum ABCC11 antibody; Monodelphis domestica ABCC11 antibody K7E6A1 86.0%
ARP43707 Gray short-tailed opossum ABCC11 antibody; Monodelphis domestica ABCC11 antibody K7E6A1 79.0%
ARP43718 Horse ABCC11 antibody; Equus caballus ABCC11 antibody F6UID9 100.0%
ARP43719 Horse ABCC11 antibody; Equus caballus ABCC11 antibody F6UID9 93.0%
ARP43707 Horse ABCC11 antibody; Equus caballus ABCC11 antibody F6UID9 86.0%
ARP43706 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66-2 100.0%
ARP43707 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66-2 100.0%
ARP43718 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66-2 100.0%
ARP43719 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66-2 100.0%
ARP43706 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66 100.0%
ARP43707 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66 100.0%
ARP43718 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66 100.0%
ARP43719 Human ABCC11 antibody; Homo sapiens ABCC11 antibody Q96J66 100.0%
ARP43664 Mouse-ear cress ABCC11 antibody; Arabidopsis thaliana ABCC11 antibody Q9C8H1 93.0%
ARP43719 Mouse-ear cress ABCC11 antibody; Arabidopsis thaliana ABCC11 antibody Q9C8H1 85.0%
ARP43706 Rabbit ABCC11 antibody; Oryctolagus cuniculus ABCC11 antibody G1SGP5 92.0%
ARP43707 Rabbit ABCC11 antibody; Oryctolagus cuniculus ABCC11 antibody G1SGP5 85.0%
ARP43719 Rabbit ABCC11 antibody; Oryctolagus cuniculus ABCC11 antibody G1SGP5 79.0%
ARP43706 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F6TCW0 100.0%
ARP43707 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F6TCW0 100.0%
ARP43718 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F6TCW0 100.0%
ARP43706 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F7H940 100.0%
ARP43707 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F7H940 100.0%
ARP43718 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F7H940 100.0%
ARP43719 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F6TCW0 93.0%
ARP43719 Rhesus macaque ABCC11 antibody; Macaca mulatta ABCC11 antibody F7H940 93.0%
ARP43707 Small-eared galago ABCC11 antibody; Otolemur garnettii ABCC11 antibody H0WU37 93.0%
ARP43706 Small-eared galago ABCC11 antibody; Otolemur garnettii ABCC11 antibody H0WU37 92.0%
ARP43719 Small-eared galago ABCC11 antibody; Otolemur garnettii ABCC11 antibody H0WU37 86.0%
ARP43706 Sumatran orangutan ABCC11 antibody; Pongo abelii ABCC11 antibody H2NQU1 100.0%
ARP43707 Sumatran orangutan ABCC11 antibody; Pongo abelii ABCC11 antibody H2NQU1 100.0%
ARP43718 Tasmanian devil ABCC11 antibody; Sarcophilus harrisii ABCC11 antibody G3WRN1 100.0%
ARP43707 Tasmanian devil ABCC11 antibody; Sarcophilus harrisii ABCC11 antibody G3WRN1 79.0%
ARP43719 Tasmanian devil ABCC11 antibody; Sarcophilus harrisii ABCC11 antibody G3WRN1 79.0%
ARP43719 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS2 100.0%
ARP43706 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS6 100.0%
ARP43718 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS6 100.0%
ARP43719 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS6 100.0%
ARP43706 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IS45 100.0%
ARP43718 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IS45 100.0%
ARP43719 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IS45 100.0%
ARP43706 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS2 100.0%
ARP43707 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS6 86.0%
ARP43707 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IS45 86.0%
ARP43707 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS2 86.0%
ARP43718 White-tufted-ear marmoset ABCC11 antibody; Callithrix jacchus ABCC11 antibody F7IKS2 79.0%

Tissue & Cell Line Gene Expression Data