Search Antibody, Protein, and ELISA Kit Solutions


Gene ID: 57505 | AARS2 Antibody Resource


AARS2 Antibody Resource
Gene Full Name: 
alanyl-tRNA synthetase 2, mitochondrial
Uniprot: 
Q5JTZ9
Protein Name: 
alanine--tRNA ligase, mitochondrial
Nucleotide: 
NM_020745
Alias: 
AARSL;COXPD8;MTALARS;MT-ALARS;
Ensembl: 
ENSG00000124608
Location: 
6p21.1
HPRD: 
12397
NCBI Gene: 
57505
MIM: 
612035

Summary: 
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]
Function: 
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain . HAMAP-Rule MF_03133
Subcellular location: 
Mitochondrion .
PTM: 
Disease: 
Combined oxidative phosphorylation deficiency 8 (COXPD8) [MIM:614096]: A mitochondrial disease characterized by a lethal infantile hypertrophic cardiomyopathy, generalized muscle dysfunction and some neurologic involvement. The liver is not affected. Note: The disease is caused by mutations affecting the gene represented in this entry.
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody OAAB04585 AARS2 antibody - C-terminal region (OAAB04585) Human WB, IHC, ELISA 400ul $289 Details
Polyclonal Antibody OAAB04586 AARS2 antibody - center region (OAAB04586) Human WB, ELISA 400ul $289 Details

Show all AARS2 antibodies


Product Images
AARS2 antibody - center region (OAAB04586) in K562 cells using Western Blot

Sample Type: K562


AARS2 Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP68779 African elephant AARS2 antibody; Loxodonta africana AARS2 antibody G3TCX9 100.0%
ARP68779 Cat AARS2 antibody; Felis catus AARS2 antibody M3WC36 86.0%
ARP68779 Chimpanzee AARS2 antibody; Pan troglodytes AARS2 antibody H2QT37 100.0%
ARP68779 Dog AARS2 antibody; Canis familiaris AARS2 antibody F1PA93 85.0%
ARP68779 European domestic ferret AARS2 antibody; Mustela putorius furo AARS2 antibody M3YMB1 86.0%
ARP68779 Horse AARS2 antibody; Equus caballus AARS2 antibody F6Y0H4 86.0%
ARP68779 Human AARS2 antibody; Homo sapiens AARS2 antibody A2VCL8 100.0%
ARP68779 Human AARS2 antibody; Homo sapiens AARS2 antibody Q5JTZ9 100.0%
ARP68779 Pig AARS2 antibody; Sus scrofa AARS2 antibody F1RQT7 79.0%
ARP68779 Rabbit AARS2 antibody; Oryctolagus cuniculus AARS2 antibody G1TSK4 86.0%
ARP68779 Rhesus macaque AARS2 antibody; Macaca mulatta AARS2 antibody F7CLL2 100.0%
ARP68779 Rhesus macaque AARS2 antibody; Macaca mulatta AARS2 antibody G7MPG7 100.0%
ARP68779 Small-eared galago AARS2 antibody; Otolemur garnettii AARS2 antibody H0WXY2 100.0%
ARP68779 Sumatran orangutan AARS2 antibody; Pongo abelii AARS2 antibody H2PJ76 100.0%
ARP68779 Tasmanian devil AARS2 antibody; Sarcophilus harrisii AARS2 antibody G3WYZ7 100.0%
ARP53434 Thirteen-lined ground squirrel AARS2 antibody; Spermophilus tridecemlineatus AARS2 antibody I3ML42 100.0%
ARP53433 Thirteen-lined ground squirrel AARS2 antibody; Spermophilus tridecemlineatus AARS2 antibody I3ML42 86.0%
ARP68779 Thirteen-lined ground squirrel AARS2 antibody; Spermophilus tridecemlineatus AARS2 antibody I3ML53 79.0%
ARP68779 White-tufted-ear marmoset AARS2 antibody; Callithrix jacchus AARS2 antibody U3B7Z9 100.0%

Tissue & Cell Line Gene Expression Data