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Gene ID: 51166 | AADAT Antibody Resource


AADAT Antibody Resource
Gene Full Name: 
aminoadipate aminotransferase
Uniprot: 
Q8N5Z0
Protein Name: 
kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Nucleotide: 
XM_005263045
Alias: 
KAT2;KATII;
Ensembl: 
ENSG00000109576
Location: 
4q33
HPRD: 
12392
NCBI Gene: 
51166
MIM: 
611754

Summary: 
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Function: 
Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).
Subcellular location: 
Mitochondrion Potential.
PTM: 
Acetylation;
Disease: 
Biotechnological use: 

Antibodies
TypeCatalogNameClonalitySpecies ReactivityApplicationSizePriceMore Info
Polyclonal Antibody ARP43535_P050 AADAT antibody - middle region (ARP43535_P050) Polyclonal Bovine, Dog, Guinea pig, Human, Mouse, Rabbit, Rat WB 50ug $289 Details
Polyclonal Antibody ARP43534_T100 AADAT antibody - N-terminal region (ARP43534_T100) Polyclonal Bovine, Dog, Human, Mouse, Rabbit, Rat IHC, WB 100ug $229 Details
Polyclonal Antibody OAEB01713 AADAT Antibody (OAEB01713) Bovine, Dog, Guinea pig, Human, Rabbit WB 0.1mg $289 Details
Polyclonal Antibody OAAB00167 AADAT antibody - center region (OAAB00167) Human WB, ELISA 400ul $289 Details

Show all AADAT antibodies


Product Images
AADAT antibody - N-terminal region (ARP43534_T100) in Human HepG2 cells using Western Blot

Sample Type: Human HepG2

AADAT antibody - N-terminal region (ARP43534_T100) in Human kidney cells using Immunohistochemistry

Sample Type: Human kidney

AADAT antibody - middle region (ARP43535_P050) in Human COLO205 cells using Western Blot

Sample Type: Human COLO205

AADAT antibody - center region (OAAB00167) in HepG2, Y79 cells using Western Blot

Sample Type: HepG2, Y79

AADAT Antibody (OAEB01713) in Human Liver cells using Western Blot

Sample Type: Human Liver


AADAT Protocols

Publications
Related Gene Trend Categories
Species
CatalogPredicted Species & TargetTarget ReferencePredicted Homology
ARP43535 Caligus rogercresseyi AADAT antibody C1BQK8 90.0%
ARP43535 African clawed frog AADAT antibody; Xenopus laevis AADAT antibody Q6IR98 100.0%
ARP43534 Bovine AADAT antibody; Bos taurus AADAT antibody Q5E9N4 93.0%
ARP43534 Bovine AADAT antibody; Bos taurus AADAT antibody F1MKS7 93.0%
ARP43535 Bovine AADAT antibody; Bos taurus AADAT antibody Q5E9N4 92.0%
ARP43535 Bovine AADAT antibody; Bos taurus AADAT antibody F1MKS7 92.0%
ARP43535 Cat AADAT antibody; Felis catus AADAT antibody M3WH83 100.0%
ARP43534 Cat AADAT antibody; Felis catus AADAT antibody M3WH83 93.0%
ARP43534 Chicken AADAT antibody; Gallus gallus AADAT antibody E1C9H5 93.0%
ARP43535 Chicken AADAT antibody; Gallus gallus AADAT antibody E1C9H5 92.0%
ARP43534 Chimpanzee AADAT antibody; Pan troglodytes AADAT antibody H2QQF3 100.0%
ARP43535 Chimpanzee AADAT antibody; Pan troglodytes AADAT antibody H2QQF3 100.0%
ARP43534 Chinese softshell turtle AADAT antibody; Pelodiscus sinensis AADAT antibody K7FQ41 93.0%
ARP43535 Chinese softshell turtle AADAT antibody; Pelodiscus sinensis AADAT antibody K7FQ41 92.0%
ARP43534 Collared flycatcher AADAT antibody; Ficedula albicollis AADAT antibody U3KA70 93.0%
ARP43535 Collared flycatcher AADAT antibody; Ficedula albicollis AADAT antibody U3KA70 92.0%
ARP43534 Dog AADAT antibody; Canis familiaris AADAT antibody E2QUN4 93.0%
ARP43535 Dog AADAT antibody; Canis familiaris AADAT antibody E2QUN4 92.0%
ARP43534 Domestic duck AADAT antibody; Anas platyrhynchos AADAT antibody U3I823 93.0%
ARP43535 Domestic duck AADAT antibody; Anas platyrhynchos AADAT antibody U3I823 92.0%
ARP43535 Duckbill platypus AADAT antibody; Ornithorhynchus anatinus AADAT antibody F6XT01 92.0%
ARP43534 Duckbill platypus AADAT antibody; Ornithorhynchus anatinus AADAT antibody F6XT01 79.0%
ARP43534 European domestic ferret AADAT antibody; Mustela putorius furo AADAT antibody M3XVN9 93.0%
ARP43535 European domestic ferret AADAT antibody; Mustela putorius furo AADAT antibody M3XVN9 92.0%
ARP43534 Giant panda AADAT antibody; Ailuropoda melanoleuca AADAT antibody G1L267 93.0%
ARP43535 Giant panda AADAT antibody; Ailuropoda melanoleuca AADAT antibody G1L267 92.0%
ARP43535 Horse AADAT antibody; Equus caballus AADAT antibody F6ZME2 100.0%
ARP43534 Horse AADAT antibody; Equus caballus AADAT antibody F6ZME2 86.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody Q4W5N8 100.0%
ARP43535 Human AADAT antibody; Homo sapiens AADAT antibody Q4W5N8 100.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody Q8N5Z0-2 100.0%
ARP43535 Human AADAT antibody; Homo sapiens AADAT antibody Q8N5Z0-2 100.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody Q8N5Z0 100.0%
ARP43535 Human AADAT antibody; Homo sapiens AADAT antibody Q8N5Z0 100.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody D6RC56 100.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody D6REB9 100.0%
ARP43534 Human AADAT antibody; Homo sapiens AADAT antibody D6RFY7 100.0%
ARP43534 Mouse AADAT antibody; Mus musculus AADAT antibody Q9WVM8 93.0%
ARP43534 Mouse AADAT antibody; Mus musculus AADAT antibody Q3UNS8 93.0%
ARP43535 Mouse AADAT antibody; Mus musculus AADAT antibody Q9WVM8 92.0%
ARP43535 Mouse AADAT antibody; Mus musculus AADAT antibody Q3UNS8 92.0%
ARP43534 Northern white-cheeked gibbon AADAT antibody; Nomascus leucogenys AADAT antibody G1R4G5 100.0%
ARP43535 Northern white-cheeked gibbon AADAT antibody; Nomascus leucogenys AADAT antibody G1R4G5 100.0%
ARP43535 Pig AADAT antibody; Sus scrofa AADAT antibody F1RIZ5 100.0%
ARP43534 Pig AADAT antibody; Sus scrofa AADAT antibody F1RIZ5 79.0%
ARP43534 Rabbit AADAT antibody; Oryctolagus cuniculus AADAT antibody U3KLU6 100.0%
ARP43535 Rabbit AADAT antibody; Oryctolagus cuniculus AADAT antibody U3KLU6 100.0%
ARP43534 Rabbit AADAT antibody; Oryctolagus cuniculus AADAT antibody G1T1G4 100.0%
ARP43535 Rabbit AADAT antibody; Oryctolagus cuniculus AADAT antibody G1T1G4 93.0%
ARP43535 Rat AADAT antibody; Rattus norvegicus AADAT antibody Q64602 92.0%
ARP43534 Rat AADAT antibody; Rattus norvegicus AADAT antibody Q64602 85.0%
ARP43534 Rhesus macaque AADAT antibody; Macaca mulatta AADAT antibody H9EWA2 100.0%
ARP43535 Rhesus macaque AADAT antibody; Macaca mulatta AADAT antibody H9EWA2 100.0%
ARP43535 Southern platyfish AADAT antibody; Xiphophorus maculatus AADAT antibody M3ZI62 92.0%
ARP43534 Southern platyfish AADAT antibody; Xiphophorus maculatus AADAT antibody M3ZI62 86.0%
ARP43535 Spotted green pufferfish AADAT antibody; Tetraodon nigroviridis AADAT antibody H3CC58 92.0%
ARP43534 Spotted green pufferfish AADAT antibody; Tetraodon nigroviridis AADAT antibody H3CC58 86.0%
ARP43535 Sumatran orangutan AADAT antibody; Pongo abelii AADAT antibody H2PER2 100.0%
ARP43534 Sumatran orangutan AADAT antibody; Pongo abelii AADAT antibody H2PER2 100.0%
ARP43535 Tasmanian devil AADAT antibody; Sarcophilus harrisii AADAT antibody G3W490 100.0%
ARP43534 Tasmanian devil AADAT antibody; Sarcophilus harrisii AADAT antibody G3W490 93.0%
ARP43535 Thirteen-lined ground squirrel AADAT antibody; Spermophilus tridecemlineatus AADAT antibody I3NB42 100.0%
ARP43535 Three-spined stickleback AADAT antibody; Gasterosteus aculeatus AADAT antibody G3Q5Q5 92.0%
ARP43535 Three-spined stickleback AADAT antibody; Gasterosteus aculeatus AADAT antibody G3Q5Q9 92.0%
ARP43534 Three-spined stickleback AADAT antibody; Gasterosteus aculeatus AADAT antibody G3Q5Q5 86.0%
ARP43534 Three-spined stickleback AADAT antibody; Gasterosteus aculeatus AADAT antibody G3Q5Q9 86.0%
ARP43535 Western clawed frog AADAT antibody; Xenopus tropicalis AADAT antibody Q5M8X7 100.0%
ARP43535 Western clawed frog AADAT antibody; Xenopus tropicalis AADAT antibody Q28I58 100.0%
ARP43534 Western clawed frog AADAT antibody; Xenopus tropicalis AADAT antibody Q5M8X7 79.0%
ARP43534 Western clawed frog AADAT antibody; Xenopus tropicalis AADAT antibody Q28I58 79.0%
ARP43535 White-tufted-ear marmoset AADAT antibody; Callithrix jacchus AADAT antibody F7I8M7 100.0%
ARP43534 White-tufted-ear marmoset AADAT antibody; Callithrix jacchus AADAT antibody F7I8M7 86.0%
ARP43534 Zebra finch AADAT antibody; Taeniopygia guttata AADAT antibody H0Z743 93.0%
ARP43535 Zebra finch AADAT antibody; Taeniopygia guttata AADAT antibody H0Z743 92.0%
ARP53154 Zebra finch AADAT antibody; Taeniopygia guttata AADAT antibody H0Z743 89.0%

Tissue & Cell Line Gene Expression Data