SCNN1B Antibody (OAAF01152)

Catalog No: OAAF01152 (Formerly GWB-ASC548)

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Nonvoltage-gated Sodium Channel 1 Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HuvEc cells, using Nonvoltage-gated Sodium Channel 1 Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human Nonvoltage-gated Sodium Channel 1.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: Nonvoltage-gated Sodium Channel 1 antibody detects endogenous levels of total Nonvoltage-gated Sodium Channel 1 protein
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC 1:50~100
  IF 1:100~500
  ELISA 1:1000
  
• Reference: Voilley N., Genomics 28:560-565(1995).
  McDonald F.J., Am. J. Physiol. 268:C1157-C1163(1995).
  Saxena A., Biochem. Biophys. Res. Commun. 252:208-213(1998).

Target Info

• Gene Symbol: SCNN1B
• Gene Full Name: sodium channel epithelial 1 subunit beta
• Alias Symbols: amiloride-sensitive sodium channel subunit beta;amiloride-sensitive sodium channel subunit beta 1;BESC1;beta-ENaC;beta-NaCH;ENaCb;ENaCbeta;epithelial Na(+) channel subunit beta;epithelial sodium channel beta-2 subunit;epithelial sodium channel beta-3 subunit;LIDLS1;mutant sodium channel epithelial 1 beta subunit;nasal epithelial sodium channel beta subunit;nonvoltage-gated sodium channel 1 subunit beta;SCNEB;sodium channel epithelial 1 beta subunit;sodium channel, non-voltage-gated 1, beta subunit.
• NCBI Gene Id: 6338
• Protein Name: Amiloride-sensitive sodium channel subunit beta
• Description of Target: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
• Uniprot ID: P51168
• Protein Accession #: NP_000327.2
• Molecular Weight: 72 kDa