SCD5 Antibody - middle region (OAAB09334)

Catalog No: OAAB09334

Size:400UL

SCD5 Antibody (Center) (Cat. #OAAB09334) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SCD5 antibody detected the SCD5 protein (arrow).

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Bovine, Human
• Product Format: Liquid PBS with 0.09% (W/V) sodium azide.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: Western blot
  Cellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein
  Tissue Location: Detected in fetal brain, and at lower levels in fetal kidney. Detected in adult brain and pancreas, and at lower levels in kidney and lung
• Reconstitution and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SCD5.
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Varies by lot. See vial for concentration.
• Intended Use: SCD5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
• Application Info: WB: 1:1000

Target Info

• Gene Symbol: SCD5
• Gene Full Name: stearoyl-CoA desaturase 5
• Alias Symbols: ACOD4;acyl-CoA-desaturase 4;DFNA79;FADS4;HSCD5;SCD2;SCD4;stearoyl-CoA 9-desaturase;stearoyl-CoA desaturase 2;stearoyl-CoA desaturase 4;stearoyl-CoA desaturase 5.
• NCBI Gene Id: 79966
• Protein Name: NP_001032671.2, NP_079182.2, Q2KIA4, Q86SK9
• Description of Target: Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.
• Uniprot ID: https://www.uniprot.org/uniprot/?query=Q2KIA4+OR+Q86SK9
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_001032671.2,NP_079182.2
• Protein Size (# AA): 147-175aa
• Molecular Weight: 38 kDa