SART3 Antibody - middle region (ARP34329_P050)

Catalog No: ARP34329_P050

WB Suggested Anti-SART3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Small Intestine

Host: Rabbit
Target Name: SART3
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 1ug/ml

Host: Rabbit
Target Name: SART3
Sample Tissue: Human A549 Whole Cell
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SART3
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 77%
• Peptide Sequence: Synthetic peptide located within the following region: VKDLRLVTNRAGKPKGLAYVEYENESQASQAVMKMDGMTIKENIIKVAIS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SART3 (ARP34329_P050) antibody is Catalog # AAP34329 (Previous Catalog # AAPP05679)
• Reference: Ewing,R.M., Mol. Syst. Biol. 3, 89 (2007)

Target Info

• Gene Symbol: SART3
• Gene Full Name: Squamous cell carcinoma antigen recognized by T cells 3
• Alias Symbols: P100, p110, DSAP1, TIP110, p110(nrb), RP11-13G14
• NCBI Gene Id: 9733
• Protein Name: Squamous cell carcinoma antigen recognized by T-cells 3
• Description of Target: SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing. The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Uniprot ID: Q15020
• Protein Accession #: NP_055521
• Nucleotide Accession #: NM_014706
• Protein Size (# AA): 963
• Molecular Weight: 110kDa
• Protein Interactions: APBB1; PRPF3; Usp15; AMOT; SF3B1; NUP160; LRPPRC; THRAP3; BCLAF1; VARS; UBC; SUMO2; RAB1A; NEFM; IARS; HIF1A; DSG2; DHX9; MEPCE; HIST2H2BE; HIST2H2AC; RNF2; BMI1; RUFY1; NRBP1; PSME4; AKAP2; COPS5; NUP50; POP7; ARHGEF10; PSMB3; PSMA5; PSMA3; POLR2H; CAST;