SAR1A Recombinant Protein (Human) (OPCA04973)

Catalog No: OPCA04973

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Liquid or Lyophilized powder
• Additional Information: Species Specificity Detail: Homo sapiens (Human)
• Reconstitution and Storage: -20°C or -80°C
• Formulation: Tris-base, 50% glycerol
• Purity: Greater than 90% as determined by SDS-PAGE.
• Peptide Sequence: MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
• Protein Sequence: MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSVLKRQGYGEGFRWLSQYID
• Storage Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Source: E.coli
• Protein Range: 1-198 aa
• Tag: N-terminal GST-tagged
• Reference: Inhibitors of COPI and COPII do not block PEX3-mediated peroxisome synthesis. South S.T., Sacksteder K.A., Li X., Liu Y., Gould S.J. J. Cell Biol. 149:1345-1360(2000)

Target Info

• Gene Symbol: SAR1A
• Gene Full Name: secretion associated Ras related GTPase 1A
• Alias Symbols: COPII-associated small GTPase;GTP-binding protein SAR1a;masra2;SAR1;SAR1 gene homolog A;SAR1 homolog A;SAR1a gene homolog 1;Sara;SARA1.
• NCBI Gene Id: 56681
• Protein Name: GTP-binding protein SAR1a
• Description of Target: Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES).
• Uniprot ID: Q9NR31
• Protein Accession #: NP_001136120
• Nucleotide Accession #: NM_001142648
• Protein Size (# AA): Recombinant
• Molecular Weight: 49.4 kDa