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Catalog No: OACA07560
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OACA07560
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for SAP18 Antibody (OACA07560) (OACA07560)
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationEnzyme-linked immunosorbent assay|Immunohistochemistry
Reconstitution and Storage-20°C or -80°C
ImmunogenRecombinant Human Histone deacetylase complex subunit SAP18 protein (2-153AA)
PurificationAffinity Purified
Preservative0.02% sodium azide
FormulationPBS with, 50% glycerol, pH7.3.
Reference[1]"Identification of a human cell growth inhibiting gene." Kim J.W.Submitted (FEB-2004). [2]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B. Submitted (JUN-2004). [3]"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004).
Gene SymbolSAP18
Gene Full NameSin3A associated protein 18
Alias Symbols18 kDa Sin3-associated polypeptide;2HOR0202;cell growth inhibiting protein 38;cell growth-inhibiting gene 38 protein;epididymis secretory sperm binding protein;histone deacetlyase complex subunit SAP18;histone deacetylase complex subunit SAP18;SAP18P;Sin3A-associated protein, 18kDa;Sin3-associated polypeptide p18;sin3-associated polypeptide, 18 kDa;sin3-associated polypeptide, p18.
NCBI Gene Id10284
Protein NameHistone deacetylase complex subunit SAP18
Description of TargetComponent of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit mRNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits the formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function.
Uniprot IDO00422
Protein Accession #NP_005861
Nucleotide Accession #NM_005870
  1. What is the species homology for "SAP18 Antibody (OACA07560)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "SAP18 Antibody (OACA07560)"?

    This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".

  3. What buffer format is "SAP18 Antibody (OACA07560)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SAP18 Antibody (OACA07560)"?

    This target may also be called "18 kDa Sin3-associated polypeptide;2HOR0202;cell growth inhibiting protein 38;cell growth-inhibiting gene 38 protein;epididymis secretory sperm binding protein;histone deacetlyase complex subunit SAP18;histone deacetylase complex subunit SAP18;SAP18P;Sin3A-associated protein, 18kDa;Sin3-associated polypeptide p18;sin3-associated polypeptide, 18 kDa;sin3-associated polypeptide, p18." in publications.

  5. What is the shipping cost for "SAP18 Antibody (OACA07560)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SAP18 Antibody (OACA07560)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SAP18 Antibody (OACA07560)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SAP18 Antibody (OACA07560)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SAP18"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SAP18"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SAP18"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SAP18"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SAP18"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SAP18"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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