SAFB Antibody - middle region : FITC (ARP74198_P050-FITC)

Catalog No: ARP74198_P050-FITC

Size:100ul

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Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human SAFB1
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: TELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKC
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SAFB (ARP74198_P050-FITC) antibody is Catalog # AAP74198

Target Info

• Gene Symbol: SAFB
• Gene Full Name: scaffold attachment factor B
• Alias Symbols: HAP, HET, SAF-B, SAFB1, SAB-B1, SAF-B1
• NCBI Gene Id: 6294
• Protein Name: scaffold attachment factor B1
• Description of Target: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q15424-2
• Protein Size (# AA): 848
• Molecular Weight: 93kDa
• Protein Interactions: SUMO3; STAU1; UBC; LGR4; SUMO1; EED; rev; TP63; IL7R; CSNK2A1; MAP1LC3A; TP53BP1; TRMT112; TMOD2; RBMX; NCSTN; ACIN1; SMU1; U2AF2; CPSF6; GCN1L1; UTP14A; USP39; SAP18; VTN; U2AF1; TPBG; SURF4; SON; SRSF7; PRKAR1A; ABCC1; LAMP2; SEPT7; AK2; ACAT1; ZC3H18;