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SAFB Antibody - middle region (ARP74198_P050)

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100 ul
$289.00
In Stock
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Conjugation Options

ARP74198_P050-FITC Conjugated

ARP74198_P050-HRP Conjugated

ARP74198_P050-Biotin Conjugated

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Gene Symbol:
SAFB
Official Gene Full Name:
scaffold attachment factor B
NCBI Gene Id:
6294
Protein Name:
scaffold attachment factor B1
Swissprot Id:
Q15424-2
Alias Symbols:
HAP, HET, SAF-B, SAFB1, SAB-B1, SAF-B1
Description of Target:
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein Size (# AA):
848
Molecular Weight:
93kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express SAFB.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express SAFB.
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of Human SAFB1
Predicted Species Reactivity:
Human
Tested Species Reactivity:
Human
Peptide Sequence:
Synthetic peptide located within the following region: TELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKC
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
SUMO3; STAU1; UBC; LGR4; SUMO1; EED; rev; TP63; IL7R; CSNK2A1; MAP1LC3A; TP53BP1; TRMT112; TMOD2; RBMX; NCSTN; ACIN1; SMU1; U2AF2; CPSF6; GCN1L1; UTP14A; USP39; SAP18; VTN; U2AF1; TPBG; SURF4; SON; SRSF7; PRKAR1A; ABCC1; LAMP2; SEPT7; AK2; ACAT1; ZC3H18;
Blocking Peptide:
For anti-SAFB (ARP74198_P050) antibody is Catalog # AAP74198
Datasheets/Manuals:
Printable datasheet for anti-SAFB (ARP74198_P050) antibody

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