RUNX3 Protein (OPPA02360)

Catalog No: OPPA02360 (Formerly GWB-BSP626)

Size:2UG

Product Info

• Predicted Species Reactivity: Human
• Product Format: RUNX3 Human solution containing 20mM Tris HCL pH-8, 0.1M NaCl, & 20% glycerol. Physical appearance: Sterile filtered colorless solution.
• Host: E. Coli
  Product Introduction: RUNX3 is part of the RUNX family that mediates the expression of genes which participate in cellular differentiation and cell cycle progression. RUNX3 heterodimer and the beta subunit form a complex that binds to the core DNA sequence 5''-PYGPYGGT-3'' found in several enhancers and promoters, and can either activate or suppress transcription. RUNX3 interacts with additional transcription factors. RUNX3 is a good candidate for gastric cancer tumor suppressor diagnosis.
  Product Description: RUNX3 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 155 amino acids (53-186 a.a.) and having a molecular mass of 17.1 kDa. The RUNX3 is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
• Reconstitution and Storage: RUNX3 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Peptide Sequence: MGSSHHHHHH SSGLVPRGSH MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK.

Target Info

• Gene Symbol: RUNX3
• Alias Symbols: AML2, CBFA3, PEBP2aC
• NCBI Gene Id: 864
• Protein Name: Runt-related transcription factor 3
• Description of Target: Recombinant Human Runt-Related Transcription Factor 3
• Uniprot ID: Q13761
• Protein Accession #: NP_001026850.1
• Protein Size (# AA): Recombinant