Search Antibody, Protein, and ELISA Kit Solutions

RUNX1T1 Antibody (OADC00048)

100ul
$319.00
In Stock
Request Bulk Order Quote

Predicted Species Reactivity:
Human
Product Format:
Liquid. Whole antiserum from rabbit containing 0.05% azide.
Clonality:
Polyclonal
Host:
Rabbit
Conjugation:
Unconjugated
Application:
CHIP
Reconstitution and Storage:
Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item:
This antibody may replace item sc-134335 from Santa Cruz Biotechnology.
Purification:
Whole antiserum
Concentration:
Undetermined, ascites
Datasheets/Manuals:
Printable datasheet for anti-RUNX1T1 (OADC00048) antibody
Preservative:
0.05% Sodium Azide
Specificity:
Polyclonal antibody raised in rabbit against human ETO (runt-related transcription factor 1; translocated to, 1 (cyclin D-related)) using two KLH-conjugated synthetic peptides containing sequences from the N-terminal and the central region of the protein, respectively.
Application Info:
CHIP: 4 ul/CHIP
ELISA: 1:100
Gene Symbol:
RUNX1T1
Official Gene Full Name:
RUNX1 translocation partner 1
Alias Symbols:
CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1, AML1-MTG8
NCBI Gene Id:
862;
Protein Name:
protein CBFA2T1
Description of Target:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Swissprot Id:
Q06455
Protein Accession #:
NP_001185554.1
Nucleotide Accession #:
NM_001198625.1
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RUNX1T1.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RUNX1T1.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...