Size:100ul
$319.00
In Stock
SKU
OADC00048
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More Information
Predicted Species Reactivity Human
Product Format Liquid. Whole antiserum from rabbit containing 0.05% azide.
Clonality Polyclonal
Host Rabbit
Conjugation Unconjugated
Application CHIP
Reconstitution and Storage Store at -20C. Avoid repeated freeze/thaw cycles.
Replacement Item This antibody may replace item sc-134335 from Santa Cruz Biotechnology.
Purification Whole antiserum
Concentration Undetermined, ascites
Datasheets/Manuals Printable datasheet for anti-RUNX1T1 (OADC00048) antibody
Preservative 0.05% Sodium Azide
Specificity Polyclonal antibody raised in rabbit against human ETO (runt-related transcription factor 1; translocated to, 1 (cyclin D-related)) using two KLH-conjugated synthetic peptides containing sequences from the N-terminal and the central region of the protein, respectively.
Application Info CHIP: 4 ul/CHIP
ELISA: 1:100
Gene Symbol RUNX1T1
Official Gene Full Name RUNX1 translocation partner 1
Alias Symbols CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1, AML1-MTG8
NCBI Gene Id 862;
Protein Name protein CBFA2T1
Description of Target This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.
Swissprot Id Q06455
Protein Accession # NP_001185554.1
Nucleotide Accession # NM_001198625.1
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RUNX1T1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RUNX1T1.
  1. What is the species homology for "RUNX1T1 Antibody (OADC00048)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "RUNX1T1 Antibody (OADC00048)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "RUNX1T1 Antibody (OADC00048)" provided in?

    This item is provided in "Liquid. Whole antiserum from rabbit containing 0.05% azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RUNX1T1 Antibody (OADC00048)"?

    This target may also be called "CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1, AML1-MTG8" in publications.

  5. What is the shipping cost for "RUNX1T1 Antibody (OADC00048)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RUNX1T1 Antibody (OADC00048)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RUNX1T1 Antibody (OADC00048)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RUNX1T1 Antibody (OADC00048)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RUNX1T1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RUNX1T1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RUNX1T1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RUNX1T1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RUNX1T1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RUNX1T1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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