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Catalog No: P100746_P050-Biotin
Size:100ul
Price: $434.00
SKU
P100746_P050-Biotin
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RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)

Datasheets/ManualsPrintable datasheet for anti-RUNX1 (P100746_P050-Biotin) antibody
Product Info
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer.
ClonalityPolyclonal
HostRabbit
ConjugationBiotin
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RUNX1
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: HPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSI
Concentration0.5 mg/ml
Blocking PeptideFor anti-RUNX1 (P100746_P050-Biotin) antibody is Catalog # AAP31063 (Previous Catalog # AAPP01801)
Sample Type Confirmation

There is BioGPS gene expression data showing that RUNX1 is expressed in PANC1

ReferenceTakeshita,M., (2008) Leukemia 22 (6), 1241-1249
Gene SymbolRUNX1
Gene Full NameRunt-related transcription factor 1
Alias SymbolsAML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha
NCBI Gene Id861
Protein NameRunt-related transcription factor 1
Description of TargetCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia. Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
Uniprot IDQ01196
Protein Accession #NP_001001890
Nucleotide Accession #NM_001001890
Protein Size (# AA)453
Molecular Weight49kDa
Protein InteractionsYAP1; UBC; HDAC11; SOX2; SMAD3; CTBP1; RUNX1; FOXP3; NCOR2; MYC; NOTCH1; UXT; CTBP2; KAT6A; PML; CREBBP; CBFB; PRMT1; HLA-DMA; HDAC2; HDAC1; CBFA2T3; RUNX1T1; CBFA2T2; ELAVL1; DNMT1; SPEN; RBM14; KMT2A; COPRS; HDAC3; TAL1; CDK1; SMARCC1; SMARCB1; SMARCA4;
  1. What is the species homology for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit".

  2. How long will it take to receive "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    This target may also be called "AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, CBF2alpha, AML1-EVI-1, PEBP2alpha" in publications.

  5. What is the shipping cost for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RUNX1 Antibody - middle region : Biotin (P100746_P050-Biotin)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RUNX1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RUNX1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RUNX1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RUNX1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RUNX1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RUNX1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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