Catalog No: ARP56211_P050-HRP
Size:100ul
Price: $434.00
SKU
ARP56211_P050-HRP
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)

Datasheets/ManualsPrintable datasheet for anti-RTKN (ARP56211_P050-HRP) antibody
Product Info
ReferenceSudo,K., (2007) Hum. Mutat. 28 (10), 1005-1013
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
ClonalityPolyclonal
HostRabbit
ConjugationHRP: Horseradish Peroxidase
ApplicationWB
Reconstitution and StorageAll conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human RTKN
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: IETPAPRKPPQALAKQGSLYHEMAIEPLDDIAAVTDILTQREGARLETPP
Concentration0.5 mg/ml
Blocking PeptideFor anti-RTKN (ARP56211_P050-HRP) antibody is Catalog # AAP56211 (Previous Catalog # AAPP38130)
Gene SymbolRTKN
Gene Full NameRhotekin
Alias Symbols-
NCBI Gene Id6242
Protein NameRhotekin
Description of TargetRTKN mediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. RTKN may play a novel role in the organization of septin structures.This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Uniprot IDQ9BST9
Protein Accession #NP_001015055
Nucleotide Accession #NM_001015055
Protein Size (# AA)563
Molecular Weight63kDa
Protein InteractionsYWHAB; RHO1; APP; RHOA; UBC; TAX1BP3; SMURF1; GOPC; RAC2; TGFBR1; RHOC; RTN4R;
  1. What is the species homology for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)" provided in?

    This item is provided in "Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    This target may also be called "-" in publications.

  5. What is the shipping cost for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "63kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RTKN Antibody - middle region : HRP (ARP56211_P050-HRP)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RTKN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RTKN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RTKN"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RTKN"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RTKN"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RTKN"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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