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- $55: Antibody & Protein in US
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| Datasheets/Manuals | Printable datasheet for anti-RSPO3 (ARP90877_P050) antibody |
|---|
| Predicted Species Reactivity | Mouse |
|---|---|
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of mouse RSPO3 |
| Purification | Affinity purified |
| Peptide Sequence | Synthetic peptide located within the following region: TSETRTCIVQRKKCSKGERGKKGRERKRKKLNKEERKETSSSSDSKGLES |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-RSPO3 (ARP90877_P050) antibody is Catalog # AAP90877 |
| Gene Symbol | RSPO3 |
|---|---|
| Gene Full Name | R-spondin 3 |
| Alias Symbols | Cri, Thsd, Thsd2, AW742308, Cristin1, 2810459H04Rik |
| NCBI Gene Id | 72780 |
| Protein Name | R-spondin-3 |
| Description of Target | Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors, which acts as a key regulator of angiogenesis. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Acts as a key regulator of angiogenesis by controlling vascular stability and pruning: acts by activating the non-canonical Wnt signaling pathway in endothelial cells. |
| Uniprot ID | Q2TJ95 |
| Protein Accession # | NP_082627.3 |
| Nucleotide Accession # | NM_028351.3 |
| Protein Size (# AA) | 277 |
| Molecular Weight | 30 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RSPO3 Antibody - middle region (ARP90877_P050)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Mouse".
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How long will it take to receive "RSPO3 Antibody - middle region (ARP90877_P050)"?
This item is available "Domestic: within 24 hours delivery | International: 3-5 days".
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What buffer format is "RSPO3 Antibody - middle region (ARP90877_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RSPO3 Antibody - middle region (ARP90877_P050)"?
This target may also be called "Cri, Thsd, Thsd2, AW742308, Cristin1, 2810459H04Rik" in publications.
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What is the shipping cost for "RSPO3 Antibody - middle region (ARP90877_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RSPO3 Antibody - middle region (ARP90877_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RSPO3 Antibody - middle region (ARP90877_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "30 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RSPO3 Antibody - middle region (ARP90877_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RSPO3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RSPO3"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RSPO3"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RSPO3"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RSPO3"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RSPO3"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.