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Catalog No: OAAB02681
Size:400ul
Price: $438.00
SKU
OAAB02681
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAAB02681
Product Info
Predicted Species ReactivityHuman
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationWB, IHC-P, FC
::Function: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.
Cellular Location: Secreted.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis RSPO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-218 amino acids from the C-terminal region of human RSPO2.
PurificationThis antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen SequenceMouse
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Intended UseRSPO2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50
Gene SymbolRSPO2
Alias SymbolsHHRRD, TETAMS2, CRISTIN2
NCBI Gene Id340419
Protein NameR-spondin-2
Description of TargetR-spondins (RSPOs), such as RSPO2, are secreted proteins that regulate beta-catenin (CTNNB1; MIM 116806) signaling.
Uniprot IDQ6UXX9
Protein Accession #NP_848660.3
Molecular Weight28 kDa
  1. What is the species homology for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "RSPO2 Antibody - C-terminal region (OAAB02681)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    This target may also be called "HHRRD, TETAMS2, CRISTIN2" in publications.

  5. What is the shipping cost for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "28 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RSPO2 Antibody - C-terminal region (OAAB02681)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RSPO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RSPO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RSPO2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RSPO2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RSPO2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RSPO2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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