RRBP1 Antibody (OAGA08354)

Catalog No: OAGA08354

Size:100 ul

Non-transfected (–) and transfected (+) HepG2 whole cell extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with Ribosome binding protein 1 antibody [GT1611] diluted at 1:500.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: GT1611
• Isotype: IgG1
• Host: Mouse
• Application: WB
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Ribosome binding protein 1. The exact sequence is proprietary.
• Purification: Affinity purified by Protein G.
• Concentration: 1.05 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: PBS

Target Info

• Gene Symbol: RRBP1
• Gene Full Name: ribosome binding protein 1
• Alias Symbols: RRp, hES, p180, ES130, ES/130
• NCBI Gene Id: 6238
• Protein Name: ribosome-binding protein 1
• Description of Target: This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12.
• Uniprot ID: Q9P2E9
• Protein Accession #: NP_001036041.1
• Nucleotide Accession #: NM_001042576.1