RPS6KB2 Antibody (Phospho-Ser423) (OASG05624)

Catalog No: OASG05624

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from human p70 S6 kinase Beta around the phosphorylation site of S423. Location: 360-440aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Phospho-Ser423
• Specificity: Phospho-p70 S6 kinase Beta (S423) Polyclonal Antibody detects endogenous levels of p70 S6 kinase Beta protein only when phosphorylated at S423.
• Application Info: WB 1:500-1:2000; ELISA 1:5000;

Target Info

• Gene Symbol: RPS6KB2
• Gene Full Name: ribosomal protein S6 kinase, 70kDa, polypeptide 2
• Alias Symbols: KLS, SRK, S6K2, S6KB, STK14B, S6KI(2), S6Kbeta, p70S6Kb, P70-beta, S6K-beta2, P70-beta-1, P70-beta-2, p70(S6K)-beta
• NCBI Gene Id: 6199; 58988;
• Description of Target: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
• Uniprot ID: Q9UBS0, Q9Z1M4
• Molecular Weight: 53 kDa