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Datasheets/Manuals | Printable datasheet for anti-RPS6KB1 (OAAJ02517) antibody |
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Predicted Species Reactivity | Human, Mouse, Rat, Pig |
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Product Format | Liquid. PBS pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Clonality | Polyclonal |
Isotype | IgG |
Host | Rabbit |
Application | WB, IHC, IF, ICC |
Additional Information | Subcellular Location: Cytoplasm; Nucleus. Cytoplasm and Cell junction > synapse > synaptosome. Mitochondrion outer membrane. Tissue Specificity: Widely expressed. Function: The autoinhibitory domain is believed to block phosphorylation within the AGC-kinase C-terminal domain and the activation loop.The TOS (TOR signaling) motif is essential for activation by mTORC1.Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. |
Reconstitution and Storage | Store at -20C. Stable for 12 months from date of receipt. |
Immunogen | A synthesized peptide derived from human p70 S6 Kinase around the phosphorylation site of Threonine 389/412 |
Purification | The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. |
Concentration | 1 mg/ml |
Specificity | Phospho-p70 S6 Kinase (Thr389/412) antibody detects endogenous levels of p70 S6 Kinase only when phosphorylated at Threonine 389/412 |
Application Info | WB: 1:500~2000 IHC: 1:50~200 IF/ICC: 1:100~500 |
Gene Symbol | RPS6KB1 |
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Gene Full Name | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
Alias Symbols | S6K, PS6K, S6K1, STK14A, p70-S6K, p70 S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha |
NCBI Gene Id | 6198 |
Description of Target | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. |
Uniprot ID | P23443 |
Molecular Weight | 70 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat, Pig".
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How long will it take to receive "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
This item is available "Domestic: within 2-3 week delivery | International: 2-3 weeks".
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What buffer format is "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)" provided in?
This item is provided in "Liquid. PBS pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
This target may also be called "S6K, PS6K, S6K1, STK14A, p70-S6K, p70 S6KA, p70-alpha, S6K-beta-1, p70(S6K)-alpha" in publications.
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What is the shipping cost for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "70 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RPS6KB1 Antibody (Phospho-Thr389/412) (OAAJ02517)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RPS6KB1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RPS6KB1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RPS6KB1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RPS6KB1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RPS6KB1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RPS6KB1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.