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RPN2 antibody - N-terminal region (ARP45400_P050)

100 ul
$319.00
In Stock

Conjugation Options

ARP45400_P050-FITC Conjugated

ARP45400_P050-HRP Conjugated

ARP45400_P050-Biotin Conjugated

Gene Symbol:
RPN2
NCBI Gene Id:
6185
Official Gene Full Name:
Ribophorin II
Protein Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Swissprot Id:
P04844
Protein Accession #:
NP_002942
Nucleotide Accession #:
NM_002951
Alias Symbols:
RIBIIR, RPN-II, RPNII, SWP1
Replacement Item:
This antibody may replace item sc-12165 from Santa Cruz Biotechnology.
Description of Target:
RPN2 is a type I integral membrane protein found only in the rough endoplasmic reticulum. The protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1.
Protein Size (# AA):
631
Molecular Weight:
69kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
IHC, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RPN2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RPN2.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human RPN2
Species Reactivity:
Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
Predicted Homology Based on Immunogen Sequence:
Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-RPN2 (ARP45400_P050)
Peptide Sequence:
Synthetic peptide located within the following region: ASQEALSALTARLSKEETVLATVQALQTASHLSQQADLRSIVEEIEDLVA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; FUS; FAF1; VAPB; EED; ADRB2; CLN3; MMS19; RCHY1; UBL4A; ESR1; RHOA; RPN1; ILF3; PDIA3; CANX; ATP5A1; STT3B; TM9SF2; FBXO6; CUL3; FBXO25; SIRT7; TCF3; AUP1; ARRB2; NDRG1; SUMO2; FBN3; RBBP4; NGFR; HDAC5; MYC; RNF185; H2AFX; BRE; ADRM1; EZH2; GSTK1; TM
Blocking Peptide:
For anti-RPN2 (ARP45400_P050) antibody is Catalog # AAP45400 (Previous Catalog # AAPP26368)
Datasheets/Manuals:
Printable datasheet for anti-RPN2 (ARP45400_P050) antibody
Sample Type Confirmation:

RPN2 is strongly supported by BioGPS gene expression data to be expressed in HepG2

Subunit:
2
Additional Information:
IHC Information: HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.
Target Reference:
Shibatani,T., (2005) Biochemistry 44 (16), 5982-5992
Publications:

Fujimoto, D; Goi, T; Hirono, Y; Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma. 50, 448-456 (2017). IHC, WB, Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat 28035352

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