RPA2 Antibody - C-terminal region : Biotin (ARP62495_P050-Biotin)

Catalog No: ARP62495_P050-Biotin

Size:100ul

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Biotin
• Application: WB
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RPA2
• Purification: Affinity Purified
• Peptide Sequence: Synthetic peptide located within the following region: SLVAFKIMPLEDMNEFTTHILEVINAHMVLSKANSQPSAGRAPISNPGMS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-RPA2 (ARP62495_P050-Biotin) antibody is Catalog # AAP62495

Target Info

• Gene Symbol: RPA2
• Alias Symbols: REPA2, RPA32, RP-A p32, RP-A p34
• NCBI Gene Id: 6118
• Description of Target: RPA2 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. FUNCTION: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.
• Uniprot ID: P15927-3
• Protein Size (# AA): 358
• Molecular Weight: 39kDa
• Protein Interactions: HUWE1; APITD1; STRA13; FBXO18; UBC; PPP1R10; PPP1CC; POLR2E; POLA1; EXOSC10; PRDX1; NUMA1; NTHL1; NPM1; NONO; NCL; NBN; HNRNPM; PPP1R12A; MYO1E; MYO1C; MYH11; MYH10; MYH9; MYO1F; MTHFD1; MSH3; MSH2; MYO1B; MRE11A; MPG; MOV10; MNAT1; RAB8A; MAP4; CAPRIN1;