RORA Antibody - middle region : FITC (ARP45607_P050-FITC)

Catalog No: ARP45607_P050-FITC

Size:100ul

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: FITC: Fluorescein Isothiocyanate
• Application: WB, IHC
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RORA
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 86%
• Peptide Sequence: Synthetic peptide located within the following region: PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDI
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-RORA (ARP45607_P050-FITC) antibody is Catalog # AAP45607 (Previous Catalog # AAPP11886)
• Reference: Boukhtouche,F., (2006) J. Neurochem. 96 (6), 1778-1789

Target Info

• Gene Symbol: RORA
• Gene Full Name: RAR-related orphan receptor A
• Alias Symbols: ROR1, ROR2, ROR3, RZRA, NR1F1, IDDECA, RZR-ALPHA
• NCBI Gene Id: 6095
• Protein Name: Nuclear receptor ROR-alpha
• Description of Target: The protein encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Four transcript variants encoding different isoforms have been described for this gene.
• Uniprot ID: P35398-3
• Protein Accession #: NP_002934
• Nucleotide Accession #: NM_002943
• Protein Size (# AA): 548
• Molecular Weight: 62kDa
• Protein Interactions: GFAP; NSD1; NCOA1; PSMC5; SMARCD3; PTBP1; VPRBP; UBC; EZH2; DDB1; LMO3; NR0B1; ZXDC; PNRC2; COPS5; PNRC1; EIF3I; PROX1; LRIF1; RUVBL1; CEBPB; NCOA2; MED1; EP300; RORA; MYOD1; NME2; NME1;