RNF2 Polyclonal Antibody (Human) (ATP00011_T100)

Catalog No: ATP00011_T100

Size:100uL

20 ug of the indicated human whole cell extract was loaded onto a 4-20% SDS-PAGE gel. After electrophoresis, proteins were transferred to a PVDF membrane and probed with 3 ug/mL of antibody. Secondary detection was performed with 0.08 ug/mL of HRP-conjugated donkey anti-rabbit IgG antibody. Images were captured after development of membrane following exposure to AvivaBlot™ Femto ECL Reagent (OKCF00002).

Immunogen: Recombinant protein representing aa 2-224 of human RNF2 (green) depicted within in the full length structure prediction (blue)  via AlphaFold. (https://alphafold.ebi.ac.uk/).

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: Recombinant Human RNF2 aa 2-224.
• Purification: Protein A Purified
• Concentration: 1mg/mL

Target Info

• Alias Symbols: BAP1;DING;BAP-1;HIPI3;RING2;LUSYAM;RING1B
• NCBI Gene Id: 6045
• Protein Name: E3 ubiquitin-protein ligase
• Description of Target: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity. [provided by RefSeq, Jul 2008]
• Uniprot ID: Q99496-1
• Protein Accession #: Q99496-1
• Molecular Weight: 38 kDa