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Catalog No: OAAB04793
Size:400ul
Price: $438.00
SKU
OAAB04793
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-RND3 antibody - OAAB04793
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeRabbit Ig
HostRabbit
ApplicationIHC-P, WB
::Function: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Cellular Location: Golgi apparatus membrane; Peripheral membrane protein.
Tissue Location Ubiquitous.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis ARHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-165 amino acids from the Central region of human ARHE.
PurificationThis antibody is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Predicted Homology Based on Immunogen SequenceRat, Pig
ConcentrationApproximately 0.5mg/ml. Actual concentration varies with each lot.
Intended UseFor research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:2000
WB: 1:1000
IHC-P: 1:10~50
Gene SymbolRND3
Alias SymbolsARHE, Rho8, RhoE, memB
NCBI Gene Id390
Protein NameRho-related GTP-binding protein RhoE
Description of TargetMembers of the Rho family of Ras-related GTPases, such as ARHE, regulate the organization of the actin cytoskeleton in response to extracellular growth factors. Like Ras (MIM 190020), Rho family members appear to cycle between an inactive GDP-bound form and an active GTP-bound form. Three major regulators of Rho activity have been identified: RhoGDIs, which interact with the GDP-bound Rho proteins to keep them in a resting complex (see MIM 601925); GEFs, which promote GDP/GTP exchange leading to activation of Rho proteins (see MIM 601855); and GAPs, which stimulate GTP hydrolysis and return the activated Rho protein to its inactive form (see MIM 602680) (Nobes et al., 1998 [PubMed 9531558]).
Uniprot IDP61587
Protein Accession #NP_001241667.1
Molecular Weight27368 Da
  1. What is the species homology for "RND3 Antibody - middle region (OAAB04793)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "RND3 Antibody - middle region (OAAB04793)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "RND3 Antibody - middle region (OAAB04793)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RND3 Antibody - middle region (OAAB04793)"?

    This target may also be called "ARHE, Rho8, RhoE, memB" in publications.

  5. What is the shipping cost for "RND3 Antibody - middle region (OAAB04793)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RND3 Antibody - middle region (OAAB04793)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RND3 Antibody - middle region (OAAB04793)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "27368 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RND3 Antibody - middle region (OAAB04793)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "RND3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RND3"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RND3"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RND3"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RND3"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RND3"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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