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RIPK2 Antibody - N-terminal region (OASA08731)

0.1 mg
$389.00
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Gene Symbol:
RIPK2
NCBI Gene Id:
8767
Protein Name:
Receptor-interacting serine/threonine-protein kinase 2
Swissprot Id:
O43353
Protein Accession #:
NP_003812.1
Alias Symbols:
CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, RIPK2
Replacement Item:
This antibody may replace item sc-136059 from Santa Cruz Biotechnology.
Description of Target:
RABBIT ANTI RIP2 (N-TERMINAL)
Protein Size (# AA):
540
Host:
Rabbit
Clonality:
Polyclonal
Application:
IHC-AFF, WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RIPK2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RIPK2.
Immunogen:
The immunogen for anti-RIPK2 antibody: a peptide corresponding to amino acids near the amino terminus of human RIP2.
Predicted Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Human
Product Format:
Purified IgG - liquid
Reconstitution and Storage:
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Datasheets/Manuals:
Printable datasheet for anti-RIPK2 antibody - OASA08731
Specificity:
RIP2
Isotype:
Polyclonal IgG
Application Info:
Immunohistology - Frozen:    10ug/ml
Western Blotting:    0.5 - 1.0ug/ml
Additional Information:
Histology Positive Control Tissue: A431 cells
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Preservative Stabilisers: 0.02% Sodium Azide (NaN3)
Antiserum Preparation: Antiserum to human RIP2 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
:::
Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline
Target Reference:
1. Inohara N., et al (1998) RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. J Biol Chem. 273:12296-300.
2. McCarthy J.V., et al (1998) RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. J Biol Chem. 273:16968-75.
3. Thome M., et al (1998) Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr Biol. 8:885-8.

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