- NCBI Gene Id:
- Protein Name:
- Receptor-interacting serine/threonine-protein kinase 2
- Alias Symbols:
- CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, RIPK2
- Replacement Item:
- This antibody may replace item sc-136059 from Santa Cruz Biotechnology.
- Description of Target:
- RABBIT ANTI RIP2 (N-TERMINAL)
- Protein Size (# AA):
- IHC-AFF, WB
- Tissue Tool:
- Find tissues and cell lines supported by DNA array analysis to express RIPK2.
- RNA Seq:
- Find tissues and cell lines supported by RNA-seq analysis to express RIPK2.
- The immunogen for anti-RIPK2 antibody: a peptide corresponding to amino acids near the amino terminus of human RIP2.
- Predicted Species Reactivity:
- Predicted Homology Based on Immunogen Sequence:
- Product Format:
- Purified IgG - liquid
- Reconstitution and Storage:
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Printable datasheet for anti-RIPK2 antibody - OASA08731
- Polyclonal IgG
- Application Info:
- Immunohistology - Frozen: 10ug/ml
Western Blotting: 0.5 - 1.0ug/ml
- Additional Information:
- Histology Positive Control Tissue: A431 cells
- Preservative Stabilisers: 0.02% Sodium Azide (NaN3)
Antiserum Preparation: Antiserum to human RIP2 (NT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer Solutions: Phosphate buffered saline
- Target Reference:
- 1. Inohara N., et al (1998) RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. J Biol Chem. 273:12296-300.
2. McCarthy J.V., et al (1998) RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. J Biol Chem. 273:16968-75.
3. Thome M., et al (1998) Identification of CARDIAK, a RIP-like kinase that associates with caspase-1. Curr Biol. 8:885-8.