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- Phone: 858-552-6979
- Email: info@avivasysbio.com
- $55: Antibody & Protein in US
- $55 + $25/Kit in US
- Contact us for international orders.
| Datasheets/Manuals | Printable datasheet for anti-RICTOR (OAEC04668) antibody |
|---|
| Predicted Species Reactivity | Human, Mouse |
|---|---|
| Product Format | Ascitic fluid containing 0.03% sodium azide |
| Clonality | Monoclonal |
| Clone | 4H5 |
| Isotype | IgG1 |
| Host | Mouse |
| Application | WB |
| Reconstitution and Storage | Store at 4C, for long term storage, store at -20C. |
| Immunogen | Purified recombinant fragment of human RICTOR expressed in E. Coli. |
| Concentration | 1 mg/ml |
| Gene Symbol | RICTOR |
|---|---|
| Gene Full Name | RPTOR independent companion of MTOR, complex 2 |
| Alias Symbols | PIA, AVO3, hAVO3 |
| NCBI Gene Id | 253260 |
| Description of Target | Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals . mTOR is a large protein kinase with two different complexes . One complex contains mTOR, GbetaL and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GbetaL, Sin1 and rictor . The mTOR-rictor complex phosphorylates Ser473 of Akt/PKB in vitro . This phosphorylation is essential for full Akt/PKB activation. Furthermore, an siRNA knockdown of rictor inhibits Ser473 phosphorylation in 3T3-L1 adipocytes . This complex has also been shown to phosphorylate the rapamycin-resistant mutants of S6K1, another effector of mTOR . |
| Uniprot ID | Q6R327 |
| Molecular Weight | 192 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "RICTOR Antibody (OAEC04668)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".
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How long will it take to receive "RICTOR Antibody (OAEC04668)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "RICTOR Antibody (OAEC04668)" provided in?
This item is provided in "Ascitic fluid containing 0.03% sodium azide".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "RICTOR Antibody (OAEC04668)"?
This target may also be called "PIA, AVO3, hAVO3" in publications.
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What is the shipping cost for "RICTOR Antibody (OAEC04668)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "RICTOR Antibody (OAEC04668)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "RICTOR Antibody (OAEC04668)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "192 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "RICTOR Antibody (OAEC04668)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "RICTOR"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "RICTOR"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "RICTOR"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "RICTOR"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "RICTOR"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "RICTOR"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
