RGS17 Antibody (OAGA00507)

Catalog No: OAGA00507

Size:100 ul

Sample (30 ug of whole cell lysate)
A: Non-transfected 293T lysates
B: RGS17 transfected 293T lysates
12% SDS PAGE
OAGA00507 diluted at 1:5000

Immunofluorescence analysis of paraformaldehyde-fixed A431, using RGS17(OAGA00507) antibody at 1:200 dilution.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: ICC, IF, WB
• Additional Information: Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq]
  Positive Controls: 293T transfected recombinant RGS17
  Cellular Localization: Membrane; Lipid-anchor, Nucleus, Cytoplasm
• Reconstitution and Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Immunogen: Synthetic peptide corresponding to a region within amino acids 148 and 210 of RGS17 (Uniprot ID#Q9UGC6)
• Purification: Purified by antigen-affinity chromatography.
• Concentration: 1 mg/ml
• Application Info: Suggested starting dilutions are as follows: WB: 1:1000-1:10000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
• Storage Buffer: 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Target Info

• Gene Symbol: RGS17
• Gene Full Name: Regulator of G-protein signaling 17
• Alias Symbols: RGSZ2, RGS-17, hRGS17
• NCBI Gene Id: 26575
• Protein Name: Regulator of G-protein signaling 17
• Uniprot ID: Q9UGC6
• Protein Accession #: NP_036551.3
• Molecular Weight: 24 kDa