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RGS17 Antibody (OAGA00507)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
ICC, IF, WB
Additional Information:
Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq]
:::
Positive Controls: 293T transfected recombinant RGS17
:::
Cellular Localization: Membrane; Lipid-anchor, Nucleus, Cytoplasm
Reconstitution and Storage:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Gene Symbol:
RGS17
Official Gene Full Name:
Regulator of G-protein signaling 17
NCBI Gene Id:
26575
Protein Name:
Regulator of G-protein signaling 17
Swissprot Id:
Q9UGC6
Protein Accession #:
NP_036551.3
Alias Symbols:
RGS-17 antibody, RGSZ2 antibody, hRGS17 antibody, RGS17 antibody, regulator of G-protein signaling 17 antibody
Replacement Item:
This antibody may replace item sc-48285 from Santa Cruz Biotechnology.
Molecular Weight:
24 kDa
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express RGS17.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express RGS17.
Immunogen:
Synthetic peptide corresponding to a region within amino acids 148 and 210 of RGS17 (Uniprot ID#Q9UGC6)
Concentration:
1 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-RGS17 antibody - OAGA00507
Application Info:
Suggested starting dilutions are as follows: WB: 1:1000-1:10000, ICC/IF: 1:100-1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Storage Buffer:
1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

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