RFK Recombinant Protein (OPCD00683)

Catalog No: OPCD00683

RFK Recombinant Protein (OPCD00683) using SDS-PAGE

RFK Recombinant Protein (OPCD00683) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Homo sapiens|Human
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Met1-His155
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 90%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: RFK
• Gene Full Name: riboflavin kinase
• Alias Symbols: 0610038L10Rik;ATP:riboflavin 5'-phosphotransferase;flavokinase;riboflavin kinase;RIFK.
• NCBI Gene Id: 55312
• Protein Name: Riboflavin kinase
• Description of Target: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.
• Uniprot ID: Q969G6
• Protein Accession #: NP_060809.3
• Nucleotide Accession #: NM_018339.5
• Protein Size (# AA): Met1~His155
• Molecular Weight: 48kDa