Size:100 ul
Special Price $229.00 Regular Price $319.00
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ARP33450_P050
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Conjugation Options

ARP33450_P050-FITC Conjugated

ARP33450_P050-HRP Conjugated

ARP33450_P050-Biotin Conjugated

RAD51 Antibody - N-terminal region (ARP33450_P050)

Rating:
100% of 100
Catalog#: ARP33450_P050
Domestic: within 1-2 days delivery | International: 1-2 days
More Information
Tested Species Reactivity Human, Mouse
Predicted Species Reactivity Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Additional Information IHC Information: Adrenal
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-36360 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human RAD51
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 100%; Dog: 93%; Goat: 77%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 93%
Complete computational species homology data Anti-RAD51 (ARP33450_P050)
Peptide Sequence Synthetic peptide located within the following region: ANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILVMAERYGLS
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-RAD51 (ARP33450_P050) antibody is Catalog # AAP33450 (Previous Catalog # AAPP04496)
Datasheets/Manuals Printable datasheet for anti-RAD51 (ARP33450_P050) antibody
Sample Type Confirmation

RAD51 is supported by BioGPS gene expression data to be expressed in HEK293T, Jurkat

Target Reference Park,J.Y., (2008) Nucleic Acids Res. 36 (10), 3226-3234
Gene Symbol RAD51
Official Gene Full Name RAD51 homolog (S. cerevisiae)
Alias Symbols BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA
NCBI Gene Id 5888
Protein Name DNA repair protein RAD51 homolog 1
Description of Target RAD51 is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist.The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. Transcript variants utilizing alternative polyA signals exist.
Swissprot Id Q06609-2
Protein Accession # NP_597994
Nucleotide Accession # NM_133487
Protein Size (# AA) 242
Molecular Weight 26kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express RAD51.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express RAD51.
Protein Interactions BRCA1; ATRX; FBXO18; PALB2; HNRNPC; SWSAP1; HNRNPA2B1; RPA3; RPA1; RAD52; PFN1; RAD54B; AICDA; BLM; DMC1; NXF1; RECQL5; UGDH; CHEK1; BRCA2; SFR1; SWI5; NEDD8; PML; TERF2IP; TP53; MSH2; MSH6; UBC; UHRF2; RAD51AP1; WRN; POLN; MORF4L1; MDC1; RAD51C; MCPH1; S
  1. What is the species homology for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish".

  2. How long will it take to receive "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "RAD51 Antibody - N-terminal region (ARP33450_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    This target may also be called "BRCC5, HRAD51, HsRad51, HsT16930, RAD51A, RECA" in publications.

  5. What is the shipping cost for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "26kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "RAD51 Antibody - N-terminal region (ARP33450_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "RAD51"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "RAD51"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "RAD51"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "RAD51"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "RAD51"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "RAD51"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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