Size:400ul
$329.00
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SKU
OAAB01511
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U2AF1 Antibody (OAAB01511)

Rating:
80% of 100
Catalog#: OAAB01511
Domestic: within 1 week delivery | International: 1 week
More Information
Predicted Species Reactivity Human
Product Format Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Rabbit Ig
Host Rabbit
Application WB, FC, IHC-P
Additional Information Function: Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Cellular Location: Nucleus. Nucleus speckle.
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-19663 from Santa Cruz Biotechnology.
Immunogen This U2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-125 amino acids from the Central region of human U2AF1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Predicted Homology Based on Immunogen Sequence Cow; Mouse
Datasheets/Manuals Printable datasheet for anti-U2AF1 antibody - OAAB01511
Intended Use For research use only and not for use in diagnostic or therapeutic procedures.
Application Info WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50
Other Applications Image 1 Data U2AF1 Antibody (Center Y114) flow cytometry analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Gene Symbol U2AF1
Alias Symbols Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 snRNP auxiliary factor small subunit, U2AF1, U2AF35, U2AFBP
NCBI Gene Id 7307
Protein Name Splicing factor U2AF 35 kDa subunit
Description of Target U2AF1 belongs to the splicing factor SR family. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers.
Swissprot Id Q01081
Protein Accession # NP_001020374.1
Molecular Weight 27872 Da (35 kDa subunit) Da
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express U2AF1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express U2AF1.
  1. What is the species homology for "U2AF1 Antibody (OAAB01511)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "U2AF1 Antibody (OAAB01511)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "U2AF1 Antibody (OAAB01511)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "U2AF1 Antibody (OAAB01511)"?

    This target may also be called "Splicing factor U2AF 35 kDa subunit, U2 auxiliary factor 35 kDa subunit, U2 snRNP auxiliary factor small subunit, U2AF1, U2AF35, U2AFBP" in publications.

  5. What is the shipping cost for "U2AF1 Antibody (OAAB01511)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "U2AF1 Antibody (OAAB01511)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "U2AF1 Antibody (OAAB01511)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "27872 Da (35 kDa subunit) Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "U2AF1 Antibody (OAAB01511)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "U2AF1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "U2AF1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "U2AF1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "U2AF1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "U2AF1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "U2AF1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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