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ATP11C Antibody - middle region (OAAB02861)

80% of 100
Catalog#: OAAB02861
Domestic: within 1 week delivery International: 1 week
More Information
Predicted Species Reactivity Human, Mouse, Hamster
Product Format Liquid. PBS with 0.09% (W/V) sodium azide.
Clonality Polyclonal
Isotype Rabbit Ig
Host Rabbit
Application WB, FC, IHC-P
:: Function: Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Required for B cell differentiation past the pro-B cell stage. Seems to mediate phosphatidylserine (PS) flipping in pro-B cells. May be involved in the transport of cholestatic bile acids (By similarity).
Cellular Location: Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A. Some cell membrane localization observed in the presence of TMEM30B.
Tissue Location Widely expressed.
Reconstitution and Storage Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-141337 from Santa Cruz Biotechnology.
Immunogen This ATP11C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of human ATP11C.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Predicted Homology Based on Immunogen Sequence Human; Mouse, Hamster
Concentration Approximately 0.5mg/ml. Actual concentration varies with each lot.
Datasheets/Manuals Printable datasheet for anti-ATP11C antibody - OAAB02861
Intended Use
For research use only and not for use in diagnostic or therapeutic procedures.
Application Info WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50
Other Applications Image 1 Data ATP11C Antibody (Center) flow cytometric analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Gene Symbol ATP11C
Alias Symbols ATP11C, ATPIQ, ATPIG, Probable phospholipid-transporting ATPase IG
NCBI Gene Id 286410
Protein Name Probable phospholipid-transporting ATPase IG
Swissprot Id Q8NB49
Protein Accession # NP_001010986.1
Molecular Weight 129477 Da
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ATP11C.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ATP11C.
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